YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|253799222, gi...
Organism:	Mycobacterium tuberculosis KZN 1435
Length:	652 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|253799222, gi....

Description	E-value	Query Range	Subject Range
gi\|121493291, gi... - gi\|121637644\|ref\|YP_977867.1\| putative nitrate reductase NarX [Mycobacterium bovis BCG str. Pasteur ... gi\|224990119, gi... - gi\|224990119\|ref\|YP_002644806.1\| putative nitrate reductase [Mycobacterium bovis BCG str. Tokyo 172]... gi\|31792924, gi\|... - gi\|31792924\|ref\|NP_855417.1\| nitrate reductase NarX [Mycobacterium bovis AF2122/97], gi\|31618515\|emb... gi\|6651231 - gi\|6651231\|gb\|AAF22229.1\|AF149772_1 fused nitrate reductase [Mycobacterium bovis BCG]	529.0	[0..1]	[652..1]
gi\|192927538, gi... - gi\|75257133\|ref\|ZP_00728669.1\| COG5013: Nitrate reductase alpha subunit [Escherichia coli E22], gi\|1...	345.0	[0..11]	[366..1]
gi\|81240717, gi\|... - gi\|82776569\|ref\|YP_402918.1\| nitrate reductase 1, alpha subunit [Shigella dysenteriae Sd197], gi\|812...	345.0	[0..11]	[366..1]
gi\|193069994, gi... - gi\|75235264\|ref\|ZP_00719501.1\| COG5013: Nitrate reductase alpha subunit [Escherichia coli E110019], ...	345.0	[0..11]	[366..1]
NARG_ECOLI - Respiratory nitrate reductase 1 alpha chain (EC 1.7.99.4) (Nitrate reductase A subunit alpha) (Quino... gi\|238900458, gi... - gi\|238900458\|ref\|YP_002926254.1\| nitrate reductase 1, alpha subunit [Escherichia coli BW2952], gi\|23... EG10638 - nitrate reductase 1, alpha subunit / Nitrate reductase I (NRA), alpha subunit EG10638 - nitrate reductase 1, alpha subunit / Nitrate reductase I (NRA), alpha subunit gi\|89108072, gi\|... - gi\|89108072\|ref\|AP_001852.1\| nitrate reductase 1, alpha subunit [Escherichia coli str. K-12 substr. ... gi\|188489238, gi... - gi\|75511742\|ref\|ZP_00734371.1\| COG5013: Nitrate reductase alpha subunit [Escherichia coli 53638], gi... gi\|170080855, gi... - gi\|170080855\|ref\|YP_001730175.1\| nitrate reductase 1, alpha subunit [Escherichia coli str. K-12 subs...	345.0	[0..11]	[366..1]
gi\|73855912, gi\|... - gi\|74312435\|ref\|YP_310854.1\| nitrate reductase 1, alpha subunit [Shigella sonnei Ss046], gi\|73855912...	345.0	[0..11]	[366..1]
gi\|110805231, gi... - gi\|110805231\|ref\|YP_688751.1\| nitrate reductase 1, alpha subunit [Shigella flexneri 5 str. 8401], gi... gi\|30040996, gi\|... - gi\|30062748\|ref\|NP_836919.1\| nitrate reductase 1 alpha subunit [Shigella flexneri 2a str. 2457T], gi...	345.0	[0..11]	[366..1]
gi\|190903320, gi... - gi\|75230214\|ref\|ZP_00716715.1\| COG5013: Nitrate reductase alpha subunit [Escherichia coli B7A], gi\|1...	345.0	[0..11]	[366..1]
gi\|15830983, gi\|... - gi\|15830983\|ref\|NP_309756.1\| nitrate reductase 1 alpha subunit [Escherichia coli O157:H7], gi\|133611... gi\|25285385, gi\|... - pir\|\|H85702 nitrate reductase 1, alpha subunit [imported] - Escherichia coli (strain O157:H7, substr... gi\|12514945, gi\|... - gi\|15801455\|ref\|NP_287472.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 EDL933], g... gi\|208737844, gi... - gi\|208822359\|ref\|ZP_03262678.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EC... gi\|209399352, gi... - gi\|209399352\|ref\|YP_002270159.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. E... gi\|209911728, gi... - gi\|209918469\|ref\|YP_002292553.1\| nitrate reductase 1 alpha subunit [Escherichia coli SE11], gi\|20991... gi\|217318678, gi... - gi\|217328251\|ref\|ZP_03444333.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. TW... gi\|218553780, gi... - gi\|218553780\|ref\|YP_002386693.1\| nitrate reductase 1, alpha subunit [Escherichia coli IAI1], gi\|2183... gi\|218351472, gi... - gi\|218694740\|ref\|YP_002402407.1\| nitrate reductase 1, alpha subunit [Escherichia coli 55989], gi\|218... gi\|253324818, gi... - gi\|254288117\|ref\|YP_003053865.1\| nitrate reductase 1, alpha subunit [Escherichia coli BL21(DE3)], gi... gi\|254161309, gi... - gi\|254161309\|ref\|YP_003044417.1\| nitrate reductase 1, alpha subunit [Escherichia coli B str. REL606]... gi\|254592097, gi... - gi\|254792697\|ref\|YP_003077534.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. T... gi\|194437089, gi... - gi\|83587368\|ref\|ZP_00925996.1\| COG5013: Nitrate reductase alpha subunit [Escherichia coli 101-1], gi... gi\|15830983, gi\|... - gi\|15830983\|ref\|NP_309756.1\| nitrate reductase 1 alpha subunit [Escherichia coli O157:H7 str. Sakai]... gi\|168771116, gi... - gi\|189360093\|gb\|EDU78512.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EC4486... gi\|187767807, gi... - gi\|187767807\|gb\|EDU31651.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EC4196... gi\|189000014, gi... - gi\|189000014\|gb\|EDU69000.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EC4076... gi\|168787731, gi... - gi\|189372492\|gb\|EDU90908.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EC869]... gi\|189376313, gi... - gi\|189376313\|gb\|EDU94729.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EC508]... gi\|170020406, gi... - gi\|170020406\|ref\|YP_001725360.1\| nitrate reductase, alpha subunit [Escherichia coli ATCC 8739], gi\|1... gi\|208806942, gi... - gi\|208806942\|ref\|ZP_03249279.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EC... gi\|208815493, gi... - gi\|208815493\|ref\|ZP_03256672.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EC... gi\|188015075, gi... - gi\|188015075\|gb\|EDU53197.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EC4113... gi\|157160734, gi... - gi\|75195377\|ref\|ZP_00705447.1\| COG5013: Nitrate reductase alpha subunit [Escherichia coli HS], gi\|15... gi\|168758152, gi... - gi\|189354962\|gb\|EDU73381.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EC4401... gi\|75190278, gi\|... - gi\|75190278\|ref\|ZP_00703545.1\| COG5013: Nitrate reductase alpha subunit [Escherichia coli E24377A], ... gi\|189365607, gi... - gi\|189365607\|gb\|EDU84023.1\| nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EC4501...	345.0	[0..11]	[366..1]
gi\|218699934, gi... - gi\|218699934\|ref\|YP_002407563.1\| nitrate reductase 1, alpha subunit [Escherichia coli IAI39], gi\|218... gi\|194426000, gi... - gi\|75212661\|ref\|ZP_00712659.1\| COG5013: Nitrate reductase alpha subunit [Escherichia coli B171], gi\|...	345.0	[0..11]	[366..1]

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Predicted Domain #1

Region A:
Residues: [1-60]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVTPRTGSR IEELLARSGR FFIPGEISAD LRTVTRRGGR DGDVFYRDRW SHDKVVRSTH  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	94.522879
Match:	1q16A
Description:	Crystal structure of Nitrate Reductase A, NarGHI, from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [61-427]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVNCTGSCSW KIYVKDDIIT WETQETDYPS VGPDRPEYEP RGCPRGAAFS WYTYSPTRVR  60
   61 HPYARGVLVE MYREAKARLG DPVAAWADIQ ADPRRRRRYQ RARGKGGLVR VSWAEATEMI 120
  121 AAAHVHTIST YGPDRVAGFS PIPAMSMVSH AAGSRFVELI GGVMTSFYDW YADLPVASPQ 180
  181 VFGDQTDVPE SGDWWDVVWQ CASVLLTYPN SRQLGTAEEL LAHIDGPAAD LLGRTVSELR 240
  241 RADPLTAATR YVDTFDLRGR ATLYLTYWTA GDTRNRGREM LAFAQTYRST DVAPPRGETP 300
  301 DFLPVVLEFA ATVDPEAGRR LLSGYRVPIA ALCNALTEAA LPYAHTVAAV CRTGDMMGEL 360
  361 FWTVVPY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.09691
Match:	1eu1A
Description:	Dimethylsulfoxide reductase (DMSO reductase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nitrate reductase activity	8.67207154808722	bayes_pls_golite062009
oxidoreductase activity, acting on other nitrogenous compounds as donors	7.49490418452899	bayes_pls_golite062009
formate dehydrogenase activity	6.68295624624715	bayes_pls_golite062009
oxidoreductase activity	2.91217637289036	bayes_pls_golite062009
catalytic activity	1.93875927205186	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	1.84836110501265	bayes_pls_golite062009
trimethylamine-N-oxide reductase activity	1.53833487723248	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	1.49405789941498	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	1.23004970625774	bayes_pls_golite062009
molybdenum ion binding	1.06869099200697	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	0.968773059107375	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.953913424085709	bayes_pls_golite062009
binding	0.91711075983007	bayes_pls_golite062009
NADH dehydrogenase activity	0.885018100222005	bayes_pls_golite062009
electron carrier activity	0.662243065357708	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	0.580090675196619	bayes_pls_golite062009
iron-sulfur cluster binding	0.552726587326143	bayes_pls_golite062009
metal cluster binding	0.552726587326143	bayes_pls_golite062009
protein binding	0.435238397559303	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	0.136519634312491	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [428-652]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTMTIVAVGS WWRYRYDKFG WTTRSSQLYE SRLLRIASPM FHFGILVVIV GHGIGLVIPQ  60
   61 SWTQAAGLSE GAYHVQAVVL GSIAGITTLA GVTLLIYRRR TRGPVFMATT VNDKVMYLVL 120
  121 VAAIVAGLGA TALGSGVVGE AYNYRETVSV WFRSVWVLQP RGDLMAEAPL YYQIHVLIGL 180
  181 ALFALWPFTR LVHAFSAPIG YLFRPYIIYR SREELVLTRP RRRGW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.522879
Match:	1q16C
Description:	Crystal structure of Nitrate Reductase A, NarGHI, from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nitrate reductase activity	8.42060418947243	bayes_pls_golite062009
oxidoreductase activity, acting on other nitrogenous compounds as donors	7.2464995846242	bayes_pls_golite062009
binding	1.18350763063367	bayes_pls_golite062009
electron carrier activity	1.14948153252384	bayes_pls_golite062009
catalytic activity	0.434711796157625	bayes_pls_golite062009
oxidoreductase activity	0.34569235854639	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: