YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|253319747, gi...
Organism:	Mycobacterium tuberculosis KZN 1435
Length:	136 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|253319747, gi....

Description	E-value	Query Range	Subject Range
MSRB_THEEB - Peptide methionine sulfoxide reductase MsrB OS=Thermosynechococcus elongatus (strain BP-1) GN=msrB P... MSRB_SYNEL - Peptide methionine sulfoxide reductase msrB OS=Synechococcus elongatus GN=msrB PE=3 SV=1	242.0	[0..3]	[135..1]
gi\|108764748, gi... - gi\|68562385\|ref\|ZP_00601648.1\| Protein of unknown function DUF25 [Rubrobacter xylanophilus DSM 9941]...	235.0	[0..2]	[133..4]
MSRB_HAHCH - Peptide methionine sulfoxide reductase MsrB OS=Hahella chejuensis (strain KCTC 2396) GN=msrB PE=3 SV...	234.0	[0..3]	[134..1]
MSRB_AGRFC - Peptide methionine sulfoxide reductase MsrB OS=Agrobacterium fabrum (strain C58 / ATCC 33970) GN=msr... gi\|25302988, gi\|... - gi\|25302988\|pir\|\|AD2688 transcription regulator Atu0908 [imported] - Agrobacterium tumefaciens (stra...	234.0	[0..1]	[133..4]
gi\|110633220, gi... - gi\|69279604\|ref\|ZP_00614410.1\| Protein of unknown function DUF25 [Mesorhizobium sp. BNC1], gi\|681898...	234.0	[0..2]	[132..6]
gi\|86558601, gi\|... - gi\|86610059\|ref\|YP_478821.1\| methionine-R-sulfoxide reductase [Synechococcus sp. JA-2-3B'a(2-13)], g... gi\|86610059 - gi\|86610059\|ref\|YP_478821.1\| methionine-R-sulfoxide reductase [Cyanobacteria bacterium Yellowstone B...	234.0	[0..4]	[135..37]
MSRB_PSEU2 - Peptide methionine sulfoxide reductase MsrB OS=Pseudomonas syringae pv. syringae (strain B728a) GN=m...	232.0	[0..3]	[135..1]
gi\|115368847, gi... - gi\|115374180\|ref\|ZP_01461467.1\| peptide methionine sulfoxide reductase MsrB [Stigmatella aurantiaca ...	232.0	[0..7]	[131..67]
gi\|87137021, gi\|... - gi\|87201340\|ref\|YP_498597.1\| protein-methionine-S-oxide reductase [Novosphingobium aromaticivorans D...	232.0	[0..3]	[134..5]
gi\|115422161, gi... - gi\|187477575\|ref\|YP_785599.1\| peptide methionine sulfoxide reductase [Bordetella avium 197N], gi\|115...	231.0	[0..3]	[135..1]

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Predicted Domain #1

Region A:
Residues: [1-136]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRPKLELSD DEWRQKLTPQ EFHVLRRAGT ERPFTGEYTD TTTAGIYQCR ACGAELFRST  60
   61 EKFESHCGWP SFFDPKSSDA VTLRPDHSLG MTRTEVLCAN CDSHLGHVFA GEGYPTPTDK 120
  121 RYCINSISLR LVPGSV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.69897
Match:	1l1dA
Description:	C-terminal MsrB domain of peptide methionine sulfoxide reductase PilB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor	5.90194589149201	bayes_pls_golite062009
protein-methionine-R-oxide reductase activity	5.64196103816384	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	3.02342037380774	bayes_pls_golite062009
peptide-methionine-(S)-S-oxide reductase activity	1.80676476343543	bayes_pls_golite062009
binding	1.67290562818139	bayes_pls_golite062009
catalytic activity	0.566791077255496	bayes_pls_golite062009
nucleic acid binding	0.555078494441175	bayes_pls_golite062009
ion binding	0.415760364192452	bayes_pls_golite062009
cation binding	0.404651661251597	bayes_pls_golite062009
metal ion binding	0.404651661251597	bayes_pls_golite062009
DNA binding	0.215568693193579	bayes_pls_golite062009
transcription regulator activity	0.183261590647643	bayes_pls_golite062009
protein binding	0.0755837372617499	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: