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View Structure Prediction Details

Protein: GME_ARATH
Organism: Arabidopsis thaliana
Length: 377 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GME_ARATH.

Description E-value Query
Range
Subject
Range
gi|41205692 - gi|41205692|gb|AAR99612.1| dTDP-glucose 4,6-dehydratase [Geobacillus stearothermophilus]
323.0 [0..28] [366..3]

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Predicted Domain #1
Region A:
Residues: [1-377]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTTNGTDYG AYTYKELERE QYWPSENLKI SITGAGGFIA SHIARRLKHE GHYVIASDWK  60
   61 KNEHMTEDMF CDEFHLVDLR VMENCLKVTE GVDHVFNLAA DMGGMGFIQS NHSVIMYNNT 120
  121 MISFNMIEAA RINGIKRFFY ASSACIYPEF KQLETTNVSL KESDAWPAEP QDAYGLEKLA 180
  181 TEELCKHYNK DFGIECRIGR FHNIYGPFGT WKGGREKAPA AFCRKAQTST DRFEMWGDGL 240
  241 QTRSFTFIDE CVEGVLRLTK SDFREPVNIG SDEMVSMNEM AEMVLSFEEK KLPIHHIPGP 300
  301 EGVRGRNSDN NLIKEKLGWA PNMRLKEGLR ITYFWIKEQI EKEKAKGSDV SLYGSSKVVG 360
  361 TQAPVQLGSL RAADGKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 80.154902
Match: 2c59A
Description: gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), with gdp-alpha-d-mannose and gdp-beta-l-galactose bound in the active site.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
UDP-glucose 4-epimerase activity 2.3391363629523 bayes_pls_golite062009
catalytic activity 2.16785883389468 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.3919444853018 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.17019598256699 bayes_pls_golite062009
dTDP-4-dehydrorhamnose reductase activity 0.835820446605149 bayes_pls_golite062009
fatty acid synthase activity 0.561621495862231 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle