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View Structure Prediction Details

Protein: MNS3_ARATH
Organism: Arabidopsis thaliana
Length: 624 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MNS3_ARATH.

Description E-value Query
Range
Subject
Range
gi|215697237, gi... - gi|215697237|dbj|BAG91231.1| unnamed protein product [Oryza sativa Japonica Group], gi|115462619|ref...
711.0 [0..5] [623..11]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSLPYSVK DIHYDNAKFR HRSPLKVFSQ SLLTLSTKRN YASCSTGKFL ILILFFGVAC  60
   61 LMLMSKSPNE SGLNEKGKVT FVGGLRL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [88-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGLLRKPPRL PPRLSPDEGQ LRGSSTNGST ISNSDPKWAA RQQSVKEAFD HAWSGYRKYA  60
   61 MGYDELMPIS QKGVDGLGGL GATVVDALDT AMIMGLDNIV SEAGSWVETH LLERISQKGQ 120
  121 VNLFETTIRV LGGLLSAYHL SGGEQGTVNM THVGPKPVIY LNIAKDLADR LLSAFTSSPT 180
  181 PVPFCDVILH ESTAHPAPGG ASSTAEVASV QLEFNYLSSI SGDPKYSTEA MKVLAHIKTL 240
  241 PKTEGLVPIY ISPQTGDFVG ENIRLGSRGD SYYEYLIKVW LQQGAKLNSN FTYLHDMYIE 300
  301 AMKGVRHLLV QNSIPKGLVF VGELPYGSKG EFSPKMDHLV CFLPGTLALG ATKGLTKEQA 360
  361 LKENLLSFED LENLKLAEDL AKTCFEMYEV TATGLAPEIA YFHTKDYTED GLDGGNKSSM 420
  421 YANDIIIKPA DRHNLLRPET VESLFVLYRI TKDTKYRDQG WQIFEAFEKY TKVKSGGYTS 480
  481 LDDVTEVPPH RRDKMETFFL GETLKYLYLL FGDDSVIPLD KFVFNTEAHP LPIRRNT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 161.0
Match: 1x9dA
Description: Crystal Structure Of Human Class I alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mannosyl-oligosaccharide mannosidase activity 7.089685350864 bayes_pls_golite062009
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity 6.95179264736435 bayes_pls_golite062009
mannosidase activity 5.20286438265852 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 4.31319275372149 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 3.65589746311782 bayes_pls_golite062009
hydrolase activity 2.67964748309919 bayes_pls_golite062009
binding 1.49199031708525 bayes_pls_golite062009
catalytic activity 1.31873306707813 bayes_pls_golite062009
cation binding 0.362242764130218 bayes_pls_golite062009
metal ion binding 0.362242764130218 bayes_pls_golite062009
protein binding 0.36081692928767 bayes_pls_golite062009
ion binding 0.355220167272296 bayes_pls_golite062009
calcium ion binding 0.121126738064555 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle