YRC Public Data Repository - Protein Structure Prediction

Protein:	RRN3
Organism:	Homo sapiens
Length:	651 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RRN3.

Description	E-value	Query Range	Subject Range
gi\|109127665 - gi\|109127665\|ref\|XP_001108222.1\| PREDICTED: similar to Tif-IA CG3278-PA isoform 2 [Macaca mulatta]	946.0	[0..1]	[651..1]
gi\|21361631, gi\|... - gi\|21361631\|ref\|NP_060897.2\| RRN3 RNA polymerase I transcription factor homolog [Homo sapiens], gi\|1...	939.0	[0..1]	[651..1]
RRN3_PONAB - RNA polymerase I-specific transcription initiation factor RRN3 OS=Pongo abelii GN=RRN3 PE=2 SV=1 RRN3_PONPY - RNA polymerase I-specific transcription initiation factor RRN3 - Pongo pygmaeus (Orangutan)	919.0	[0..1]	[651..1]
gi\|73959061 - gi\|73959061\|ref\|XP_536965.2\| PREDICTED: similar to RRN3 RNA polymerase I transcription factor homolo...	909.0	[0..1]	[651..1]
RRN3_MOUSE - RNA polymerase I-specific transcription initiation factor RRN3 OS=Mus musculus GN=Rrn3 PE=1 SV=1	893.0	[0..1]	[651..1]
gi\|109489580, gi... - gi\|109489580\|ref\|XP_001075816.1\| PREDICTED: similar to RRN3 RNA polymerase I transcription factor ho...	887.0	[0..1]	[651..1]
gi\|114661146 - gi\|114661146\|ref\|XP_001143837.1\| PREDICTED: RRN3 RNA polymerase I transcription factor homolog, part...	812.0	[0..79]	[651..23]
gi\|167555129, gi... - gi\|84105561\|gb\|AAI11507.1\| LOC443681 protein [Xenopus laevis], gi\|167555129\|ref\|NP_001107876.1\| hypo...	740.0	[0..34]	[646..1]

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Predicted Domain #1

Region A:
Residues: [1-140]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAPLLHTRL PGDAAASSSA VKKLGASRTG ISNMRALEND FFNSPPRKTV RFGGTVTEVL  60
   61 LKYKKGETND FELLKNQLLD PDIKDDQIIN WLLEFRSSIM YLTKDFEQLI SIILRLPWLN 120
  121 RSQTVVEEYL AFLGNLVSAQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [141-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVFLRPCLSM IASHFVPPRV IIKEGDVDVS DSDDEDDNLP ANFDTCHRAL QIIARYVPST  60
   61 PWFLMPILVE KFPFVRKSER TLECYVHNLL RISVYFPTLR HEILELIIEK LLKLDVNASR 120
  121 QGIEDAEETA TQTCGGTDST EGLFNMDEDE ETEHETKA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [299-442]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPERLDQMVH PVAERLDILM SLVLSYMKDV CYVDGKVDNG KTKDLYRDLI NIFDKLLLPT  60
   61 HASCHVQFFM FYLCSFKLGF AEAFLEHLWK KLQDPSNPAI IRQAAGNYIG SFLARAKFIP 120
  121 LITVKSCLDL LVNWLHIYLN NQDS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [443-581]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTKAFCDVAL HGPFYSACQA VFYTFVFRHK QLLSGNLKEG LQYLQSLNFE RIVMSQLNPL  60
   61 KICLPSVVNF FAAITNKYQL VFCYTIIERN NRQMLPVIRS TAGGDSVQIC TNPLDTFFPF 120
  121 DPCVLKRSKK FIDPIYQVW

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [582-651]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDMSAEELQE FKKPMKKDIV EDEDDDFLKG EVPQNDTVIG ITPSSFDTHF RSPSSSVGSP  60
   61 PVLYMQPSPL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits