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View Structure Prediction Details

Protein: gi|51247661
Organism: Homo sapiens
Length: 234 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|51247661.

Description E-value Query
Range
Subject
Range
gi|67970545 - gi|67970545|dbj|BAE01615.1| unnamed protein product [Macaca fascicularis]
259.0 [0..5] [230..45]
gi|109105619 - gi|109105619|ref|XP_001115486.1| PREDICTED: OTU domain, ubiquitin aldehyde binding 1 [Macaca mulatta...
258.0 [0..5] [230..47]
gi|73951198 - gi|73951198|ref|XP_533248.2| PREDICTED: similar to Ubiquitin thiolesterase protein OTUB1 (Otubain 1)...
257.0 [0..5] [230..52]
gi|114638245 - gi|114638245|ref|XP_001162861.1| PREDICTED: similar to OTU domain, ubiquitin aldehyde binding 1 isof...
256.0 [0..5] [230..12]
gi|74182906 - gi|74182906|dbj|BAE20433.1| unnamed protein product [Mus musculus]
255.0 [0..5] [230..44]
gi|6841176 - gi|6841176|gb|AAF28941.1|AF161381_1 HSPC263 [Homo sapiens]
255.0 [0..5] [230..48]

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Predicted Domain #1
Region A:
Residues: [1-234]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSETSFNLIS EKCDILSILR DHPENRIYRR KIEELSKRFT AIRKTKGDRN CFYRALGYSY  60
   61 LESLLGKSRE IFKFKERVLQ TPNDLLAAGF EEHKFRNFFN AFYSVVELVE KDGSVSSLLK 120
  121 VFNDQSASDH IVQFLRLLTS AFIRNRADFF RHFIDEEXDI KDFCTHEVEP XATECDHIQI 180
  181 TALSQALSIA LQVEYVDEMD TALNHHVFPE AATPSVYLLY KTSHYNILYA ADKH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.30103
Match: 1tffA
Description: Structure of Otubain-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.05972260874031 bayes_pls_golite062009
cysteine-type peptidase activity 0.425816187034917 bayes_pls_golite062009
hydrolase activity 0.357802432053114 bayes_pls_golite062009
peptidase activity 0.346526895553696 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.243518492883819 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle