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View Structure Prediction Details

Protein: gi|47169179, gi|...
Organism: Homo sapiens
Length: 344 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|47169179, gi|....

Description E-value Query
Range
Subject
Range
GALM_RAT - Aldose 1-epimerase OS=Rattus norvegicus GN=Galm PE=1 SV=1
406.0 [0..3] [344..1]
GALM - galactose mutarotase (aldose 1-epimerase)
402.0 [0..3] [344..1]
GALM_MOUSE - Aldose 1-epimerase OS=Mus musculus GN=Galm PE=1 SV=1
401.0 [0..3] [344..1]
GALM_BOVIN - Aldose 1-epimerase OS=Bos taurus GN=GALM PE=2 SV=1
400.0 [0..3] [344..1]
GALM_PIG - Aldose 1-epimerase OS=Sus scrofa GN=GALM PE=2 SV=1
399.0 [0..3] [344..1]
GALM_PONPY - Aldose 1-epimerase - Pongo pygmaeus (Orangutan)
GALM_PONAB - Aldose 1-epimerase OS=Pongo abelii GN=GALM PE=2 SV=1
399.0 [0..3] [344..1]
gi|73980750 - gi|73980750|ref|XP_540154.2| PREDICTED: similar to galactose mutarotase (aldose 1-epimerase) [Canis ...
397.0 [0..3] [344..1]
gi|62857539 - gi|62857539|ref|NP_001017024.1| galactose mutarotase (aldose 1-epimerase) [Xenopus tropicalis]
384.0 [0..3] [344..1]

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Predicted Domain #1
Region A:
Residues: [1-344]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHMASVTRAV FGELPSGGGT VEKFQLQSDL LRVDIISWGC TITALEVKDR QGRASDVVLG  60
   61 FAELEGYLQK QPYFGAVIGR VANRIAKGTF KVDGKEYHLA INKEPNSLHG GVRGFDKVLW 120
  121 TPRVLSNGVQ FSRISPDGEE GYPGELKVWV TYTLDGGELI VNYRAQASQA TPVNLTNHSY 180
  181 FNLAGQASPN INDHEVTIEA DTYLPVDETL IPTGEVAPVQ GTAFDLRKPV ELGKHLQDFH 240
  241 LNGFDHNFCL KGSKEKHFCA RVHHAASGRV LEVYTTQPGV QFYTGNFLDG TLKGKNGAVY 300
  301 PKHSGFCLET QNWPDAVNQP RFPPVLLRPG EEYDHTTWFK FSVA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 114.0
Match: 1snzA
Description: Crystal structure of apo human galactose mutarotase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aldose 1-epimerase activity 2.85100059704396 bayes_pls_golite062009
catalytic activity 0.770933849734279 bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives 0.68102716507433 bayes_pls_golite062009
racemase and epimerase activity 0.473636146090495 bayes_pls_golite062009
UDP-glucose 4-epimerase activity 0.46846097606394 bayes_pls_golite062009
binding 0.381228414514023 bayes_pls_golite062009
isomerase activity 0.106573908779409 bayes_pls_golite062009
protein binding 0.078592895113726 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle