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View Structure Prediction Details

Protein: gi|220954206, gi...
Organism: synthetic construct
Length: 281 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|220954206, gi....

Description E-value Query
Range
Subject
Range
gi|34849506, gi|... - gi|41053431|ref|NP_956973.1| Ly1 antibody reactive homolog [Danio rerio], gi|34849506|gb|AAH58310.1|...
260.0 [0..1] [279..1]
gi|21536909 - gi|21536909|gb|AAM61241.1| unknown [Arabidopsis thaliana]
249.0 [0..1] [281..1]
gi|39581890, gi|... - gi|39581890|emb|CAE72852.1| Hypothetical protein CBG20151 [Caenorhabditis briggsae], gi|187023628|em...
gi|157776197 - gi|157776197|ref|XP_001666164.1| hypothetical protein CBG20151 [Caenorhabditis briggsae AF16]
249.0 [0..1] [279..1]
CE01499 - cell growth regulating protein status:Confirmed UniProt:Q09464 protein_id:CAA86746.1
234.0 [0..1] [280..1]
gi|115437932, gi... - gi|115437932|ref|NP_001043416.1| Os01g0583200 [Oryza sativa (japonica cultivar-group)], gi|113532947...
228.0 [0..1] [281..19]
gi|54635998, gi|... - gi|54635998|gb|EAL25401.1| GA11899-PA [Drosophila pseudoobscura], gi|125808676|ref|XP_001360826.1| G...
220.0 [0..1] [278..1]
gi|26345614 - gi|26345614|dbj|BAC36458.1| unnamed protein product [Mus musculus]
210.0 [0..1] [183..1]

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Predicted Domain #1
Region A:
Residues: [1-63]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFFTCNICG ESVKKPAVEK HYQTRCRGKD KNVSCMDCLK DFYGEEYVAH IKCISEAQKY  60
   61 ASQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.154902
Match: 1wjvA
Description: Solution structure of the N-terminal zinc finger domain of mouse cell growth regulating nucleolar protein LYAR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.75384162940108 bayes_pls_golite062009
nucleic acid binding 1.57776971811162 bayes_pls_golite062009
DNA binding 1.44675129642632 bayes_pls_golite062009
transcription regulator activity 1.20428473898846 bayes_pls_golite062009
transcription factor activity 0.35678698773089 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [64-156]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQGFAAKEPR NKNAQKQESW MDIIRSILDS SEYNLTPAVR SAFQKLQSVD NVPRKKAKFE  60
   61 NFVGNCMRMP RNQATQVWDI LEKELNKMKE AKQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.556 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.504 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.444 a.118.1 ARM repeat
View Download 0.366 a.79.1 Antitermination factor NusB
View Download 0.356 a.118.8 TPR-like

Predicted Domain #3
Region A:
Residues: [157-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AELARAKAEK IAEIQQKQKA EVEEEAPPKK KAKVETTEDA AAEETSNGVT SDFDWAAQLT  60
   61 KIVTKQADGI FLEKLRKKLL KKYAKHLSVE DLNEKQAKKF QKRFDKQLKL ADSLEVEGEI 120
  121 VKIAS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.687 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.484 N/A N/A a.25.1 Ferritin-like
View Download 0.465 N/A N/A d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.435 N/A N/A a.72.1 Functional domain of the splicing factor Prp18
View Download 0.430 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle