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View Structure Prediction Details

Protein: gi|220957392, gi...
Organism: synthetic construct
Length: 276 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|220957392, gi....

Description E-value Query
Range
Subject
Range
WBS22_MOUSE - Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Mus musculus GN=Wbscr22 PE=1 SV=1
248.0 [0..2] [276..5]
gi|169642269, gi... - gi|62658761|ref|XP_347255.2| PREDICTED: similar to Putative methyltransferase WBSCR22 (Williams-Beur...
247.0 [0..2] [276..5]
WBS22_BOVIN - Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Bos taurus GN=WBSCR22 PE=2 SV=1
236.0 [0..3] [276..6]
WBSCR22 - Williams Beuren syndrome chromosome region 22
231.0 [0..3] [276..6]
gi|86129594, gi|... - gi|86129594|ref|NP_001034421.1| Williams Beuren syndrome chromosome region 22 [Gallus gallus], gi|53...
227.0 [0..3] [276..6]
gi|66564535 - gi|66564535|ref|XP_623810.1| PREDICTED: similar to CG10903-PA [Apis mellifera]
227.0 [0..1] [272..1]
gi|57087473 - gi|57087473|ref|XP_536843.1| PREDICTED: similar to Putative methyltransferase HUSSY-03 (Williams-Beu...
226.0 [0..3] [276..6]
gi|54639331|gb|E... - GA10628-PA [Drosophila pseudoobscura], GA10628 [Drosophila pseudoobscura pseudoobscura]
gi|54639331, gi|... - gi|54639331|gb|EAL28733.1| GA10628 [Drosophila pseudoobscura pseudoobscura], gi|125777365|ref|XP_001...
226.0 [0..1] [276..1]

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Predicted Domain #1
Region A:
Residues: [1-276]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARRPEHSAP PEIFYNDDEA KKYSTNTRII EIQVEMAERA LELLALPDDD ESRLILDIGC  60
   61 GSGLSGSVLE DSEHMWIGID ISKSMLDIAV EREVAGDVIL GDMGEGMPFK PGTFDGAISI 120
  121 SALQWLCNAD KSYHNPHKRL LKFFTTLFSC LTRTARAVFQ FYPENSDQIE MVTSQAMKAG 180
  181 FYGGLVVDYP NSAKAKKYYL VLMTGGSAEL PQALGSPEEE RRVNYIKKRD ACREARGKAP 240
  241 KKSRDWILAK KERRRRQGLE TRPDTKYTAR KRSGKF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 2avnA
Description: Crystal structure of Ubiquinone/menaquinone biosynthesis methyltransferase-related protein (tm1389) from THERMOTOGA MARITIMA at 2.35 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
rRNA methyltransferase activity 4.09362182773099 bayes_pls_golite062009
N-methyltransferase activity 4.00768472859991 bayes_pls_golite062009
methyltransferase activity 3.57681394097837 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 3.49392219433935 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.39429041855776 bayes_pls_golite062009
RNA methyltransferase activity 3.07428840534971 bayes_pls_golite062009
transferase activity 2.926540904444 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 1.83964463328968 bayes_pls_golite062009
tRNA methyltransferase activity 1.76571145896453 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 1.75675289134467 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 1.10713374933008 bayes_pls_golite062009
protein methyltransferase activity 0.94499223839747 bayes_pls_golite062009
transcription regulator activity 0.914549843668268 bayes_pls_golite062009
DNA binding 0.86027591375666 bayes_pls_golite062009
binding 0.777596419415505 bayes_pls_golite062009
nucleic acid binding 0.616949327277483 bayes_pls_golite062009
RNA binding 0.417524996559564 bayes_pls_golite062009
O-methyltransferase activity 0.250946859465502 bayes_pls_golite062009
histone methyltransferase activity 0.0408000230099101 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle