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View Structure Prediction Details

Protein: gi|221315186
Organism: Bacillus subtilis subsp. subtilis str. NCIB 3610
Length: 319 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|221315186.

Description E-value Query
Range
Subject
Range
gi|229331701, gi... - gi|229497223|ref|ZP_04390924.1| 6-phosphofructokinase [Geobacillus sp. Y412MC52], gi|229331701|gb|EE...
gi|220707901, gi... - gi|221088139|ref|ZP_03557672.1| 6-phosphofructokinase [Geobacillus sp. Y412MC61], gi|220707901|gb|EE...
PFKA_GEOKA - ATP-dependent 6-phosphofructokinase OS=Geobacillus kaustophilus (strain HTA426) GN=pfkA PE=3 SV=1
K6PF_GEOKA - 6-phosphofructokinase OS=Geobacillus kaustophilus GN=pfkA PE=3 SV=1
409.0 [0..1] [319..1]

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Predicted Domain #1
Region A:
Residues: [1-319]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRIGVLTSG GDSPGMNAAV RAVVRKAIYH DVEVYGIYNG YAGLISGKIE KLELGSVGDI  60
   61 IHRGGTKLYT ARCPEFKTVE GREKGIANLK KLGIEGLVVI GGDGSYMGAK KLTEHGFPCV 120
  121 GVPGTIDNDI PGTDFTIGFD TALNTVIDAI DKIRDTATSH ERTYVIEVMG RHAGDIALWA 180
  181 GLAGGAESIL IPEADYDMHE IIARLKRGHE RGKKHSIIIV AEGVGSGVEF GKRIEEETNL 240
  241 ETRVSVLGHI QRGGSPSAAD RVLASRLGAY AVELLLEGKG GRCVGIQNNK LVDHDIIEIL 300
  301 ETKHTVEQNM YQLSKELSI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 113.0
Match: 6pfkA
Description: ATP-dependent phosphofructokinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
6-phosphofructokinase activity 12.7403693686468 bayes_pls_golite062009
phosphofructokinase activity 11.7059647240147 bayes_pls_golite062009
carbohydrate kinase activity 9.54757838113048 bayes_pls_golite062009
fructose-6-phosphate binding 7.12870468168491 bayes_pls_golite062009
fructose binding 7.0070117394116 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 2.40595318732289 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.20407391743017 bayes_pls_golite062009
kinase activity 2.09076306615481 bayes_pls_golite062009
transferase activity 1.97789134877808 bayes_pls_golite062009
catalytic activity 1.89212073381079 bayes_pls_golite062009
monosaccharide binding 0.93954836516667 bayes_pls_golite062009
binding 0.692710585652872 bayes_pls_golite062009
hydrolase activity 0.276140444059183 bayes_pls_golite062009
fructose-2,6-bisphosphate 2-phosphatase activity 0.13423626204854 bayes_pls_golite062009
sugar binding 0.0026978348896064 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle