YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|214002811
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E98-3139
Length:	447 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|214002811.

Description	E-value	Query Range	Subject Range
gi\|193063674, gi... - gi\|193063674\|ref\|ZP_03044762.1\| putative transporter [Escherichia coli E22], gi\|192930661\|gb\|EDV8326... gi\|194426533, gi... - gi\|194426533\|ref\|ZP_03059087.1\| putative transporter [Escherichia coli B171], gi\|194415272\|gb\|EDX315... gi\|187730274, gi... - gi\|187730274\|ref\|YP_001882995.1\| putative transporter [Shigella boydii CDC 3083-94], gi\|187427266\|gb... gi\|190902708, gi... - gi\|191167255\|ref\|ZP_03029073.1\| putative transporter [Escherichia coli B7A], gi\|190902708\|gb\|EDV6243... gi\|82779478, gi\|... - gi\|82779478\|ref\|YP_405827.1\| putative transport protein [Shigella dysenteriae Sd197], gi\|81243626\|gb... gi\|81247942, gi\|... - gi\|82546531\|ref\|YP_410478.1\| putative transport protein [Shigella boydii Sb227], gi\|81247942\|gb\|ABB6... gi\|73858176, gi\|... - gi\|74314699\|ref\|YP_313118.1\| putative transport protein [Shigella sonnei Ss046], gi\|73858176\|gb\|AAZ9... gi\|110617584, gi... - gi\|110808036\|ref\|YP_691556.1\| putative transport protein [Shigella flexneri 5 str. 8401], gi\|1106175... gi\|30043754, gi\|... - gi\|30065490\|ref\|NP_839661.1\| putative transport protein [Shigella flexneri 2a str. 2457T], gi\|300437... gi\|157069372, gi... - gi\|157163692\|ref\|YP_001461010.1\| putative transporter [Escherichia coli HS], gi\|157069372\|gb\|ABV0862... gi\|157079304, gi... - gi\|157157274\|ref\|YP_001465725.1\| putative transporter [Escherichia coli E24377A], gi\|157079304\|gb\|AB... gi\|24115470, gi\|... - gi\|24115470\|ref\|NP_709980.1\| putative transport protein [Shigella flexneri 2a str. 301], gi\|24054790... gi\|218697970, gi... - gi\|218697970\|ref\|YP_002405637.1\| conserved hypothetical protein; putative inner membrane protein [Es... gi\|254037238, gi... - gi\|254037238\|ref\|ZP_04871315.1\| conserved hypothetical protein [Escherichia sp. 1_1_43], gi\|22684034... gi\|194433889, gi... - gi\|194433889\|ref\|ZP_03066162.1\| putative transporter [Shigella dysenteriae 1012], gi\|194417870\|gb\|ED... gi\|218556770, gi... - gi\|218556770\|ref\|YP_002389684.1\| conserved hypothetical protein; putative inner membrane protein [Es...	2.0E-83	[1..447]	[1..447]
YTFL_ECOL6 - UPF0053 inner membrane protein YtfL OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) G... YTFL_ECO57 - UPF0053 inner membrane protein YtfL OS=Escherichia coli O157:H7 GN=ytfL PE=3 SV=1 gi\|227836303, gi... - gi\|227886730\|ref\|ZP_04004535.1\| hemolysin [Escherichia coli 83972], gi\|227836303\|gb\|EEJ46769.1\| hemo... EG12512 - UPF0053 family inner membrane protein / Inner membrane protein, UPF0053 family, function unknown gi\|85676969, gi\|... - gi\|89110938\|ref\|AP_004718.1\| predicted inner membrane protein [Escherichia coli str. K-12 substr. W3... gi\|15804809, gi\|... - gi\|15804809\|ref\|NP_290850.1\| putative transport protein [Escherichia coli O157:H7 EDL933], gi\|125192... YTFL_ECOL6 - UPF0053 inner membrane protein ytfL OS=Escherichia coli O6 GN=ytfL PE=3 SV=1 gi\|251787471, gi... - gi\|251787471\|ref\|YP_003001775.1\| hypothetical protein B21_04052 [Escherichia coli BL21], gi\|24237974... gi\|238862528, gi... - gi\|238903324\|ref\|YP_002929120.1\| putative inner membrane protein [Escherichia coli BW2952], gi\|23886... gi\|253976052, gi... - gi\|254164151\|ref\|YP_003047259.1\| predicted inner membrane protein [Escherichia coli B str. REL606], ... gi\|253326197, gi... - gi\|254290901\|ref\|YP_003056649.1\| predicted inner membrane protein [Escherichia coli BL21(DE3)], gi\|2... gi\|254595639, gi... - gi\|254796239\|ref\|YP_003081076.1\| predicted inner membrane protein [Escherichia coli O157:H7 str. TW1... gi\|188491709, gi... - gi\|188491709\|ref\|ZP_02998979.1\| putative transporter [Escherichia coli 53638], gi\|188486908\|gb\|EDU62... gi\|91213775, gi\|... - gi\|91213775\|ref\|YP_543761.1\| putative transport protein [Escherichia coli UTI89], gi\|91075349\|gb\|ABE... gi\|13364673, gi\|... - gi\|15834450\|ref\|NP_313223.1\| putative transport protein [Escherichia coli O157:H7 str. Sakai], gi\|13... gi\|170679891, gi... - gi\|170679891\|ref\|YP_001746620.1\| putative transporter [Escherichia coli SMS-3-5], gi\|170517609\|gb\|AC... gi\|170083662, gi... - gi\|170083662\|ref\|YP_001732982.1\| inner membrane protein [Escherichia coli str. K-12 substr. DH10B], ... gi\|110644583, gi... - gi\|110644583\|ref\|YP_672313.1\| hypothetical protein ECP_4471 [Escherichia coli 536], gi\|110346175\|gb\|... gi\|169756695, gi... - gi\|170021767\|ref\|YP_001726721.1\| hypothetical protein EcolC_3789 [Escherichia coli ATCC 8739], gi\|16... gi\|195937245 - gi\|195937245\|ref\|ZP_03082627.1\| inner membrane protein [Escherichia coli O157:H7 str. EC4024] gi\|194437782, gi... - gi\|194437782\|ref\|ZP_03069877.1\| putative transporter [Escherichia coli 101-1], gi\|194423278\|gb\|EDX39... gi\|124528284, gi... - gi\|124528284\|ref\|ZP_01699608.1\| protein of unknown function DUF21 [Escherichia coli B], gi\|124500726... gi\|193069850, gi... - gi\|193069850\|ref\|ZP_03050800.1\| putative transporter [Escherichia coli E110019], gi\|192956904\|gb\|EDV... gi\|190908979, gi... - gi\|191170755\|ref\|ZP_03032307.1\| putative transporter [Escherichia coli F11], gi\|190908979\|gb\|EDV6856... gi\|115515692, gi... - gi\|117626568\|ref\|YP_859891.1\| putative transport protein [Escherichia coli APEC O1], gi\|115515692\|gb... gi\|168766502, gi... - gi\|189364125\|gb\|EDU82544.1\| putative transporter [Escherichia coli O157:H7 str. EC4486], gi\|16876650... gi\|189368918, gi... - gi\|189368918\|gb\|EDU87334.1\| putative transporter [Escherichia coli O157:H7 str. EC4501], gi\|16876046... gi\|168754793, gi... - gi\|189357815\|gb\|EDU76234.1\| putative transporter [Escherichia coli O157:H7 str. EC4401], gi\|16875479... gi\|168751092, gi... - gi\|188014846\|gb\|EDU52968.1\| putative transporter [Escherichia coli O157:H7 str. EC4113], gi\|16875109... gi\|168797792, gi... - gi\|189379597\|gb\|EDU98013.1\| putative transporter [Escherichia coli O157:H7 str. EC508], gi\|168797792... gi\|189374775, gi... - gi\|189374775\|gb\|EDU93191.1\| putative transporter [Escherichia coli O157:H7 str. EC869], gi\|168784860... gi\|188999763, gi... - gi\|188999763\|gb\|EDU68749.1\| putative transporter [Escherichia coli O157:H7 str. EC4076], gi\|16878273... gi\|187770191, gi... - gi\|187770191\|gb\|EDU34035.1\| putative transporter [Escherichia coli O157:H7 str. EC4196], gi\|16877406... gi\|218707831, gi... - gi\|218707831\|ref\|YP_002415350.1\| conserved hypothetical protein; putative inner membrane protein [Es... gi\|218372907, gi... - gi\|218702921\|ref\|YP_002410550.1\| conserved hypothetical protein; putative inner membrane protein [Es... gi\|218692609, gi... - gi\|218692609\|ref\|YP_002400821.1\| conserved hypothetical protein; putative inner membrane protein [Es... YTFL_ECOLI - UPF0053 inner membrane protein ytfL - Escherichia coli gi\|209400045, gi... - gi\|209400045\|ref\|YP_002273761.1\| putative transporter [Escherichia coli O157:H7 str. EC4115], gi\|209... gi\|208741498, gi... - gi\|208821375\|ref\|ZP_03261695.1\| putative transporter [Escherichia coli O157:H7 str. EC4042], gi\|2087... gi\|208733775, gi... - gi\|208812498\|ref\|ZP_03253827.1\| putative transporter [Escherichia coli O157:H7 str. EC4045], gi\|2087... gi\|208809492, gi... - gi\|208809492\|ref\|ZP_03251829.1\| putative transporter [Escherichia coli O157:H7 str. EC4206], gi\|2087... gi\|218561382, gi... - gi\|218561382\|ref\|YP_002394295.1\| conserved hypothetical protein; putative inner membrane protein [Es... gi\|217322190, gi... - gi\|217325969\|ref\|ZP_03442053.1\| putative transporter [Escherichia coli O157:H7 str. TW14588], gi\|217... gi\|215267639, gi... - gi\|215489567\|ref\|YP_002331998.1\| predicted inner membrane protein [Escherichia coli O127:H6 str. E23... gi\|209914973, gi... - gi\|209921714\|ref\|YP_002295798.1\| putative transport protein [Escherichia coli SE11], gi\|209914973\|db... EG12512 - UPF0053 family inner membrane protein / Inner membrane protein, UPF0053 family, function unknown	3.0E-83	[1..447]	[1..447]
gi\|17134355, gi\|... - gi\|17232708\|ref\|NP_489256.1\| hypothetical protein alr5216 [Nostoc sp. PCC 7120], gi\|17134355\|dbj\|BAB... gi\|25302934 - pir\|\|AH2457 hypothetical protein alr5216 [imported] - Nostoc sp. (strain PCC 7120)	6.0E-83	[1..435]	[4..441]
gi\|147920421, gi... - gi\|147920421\|ref\|YP_685804.1\| hypothetical protein RCIX1155 [uncultured methanogenic archaeon RC-I],...	1.0E-81	[1..435]	[4..438]
gi\|110595716, gi... - gi\|110595716\|ref\|ZP_01384043.1\| conserved hypothetical protein [Acidovorax sp. JS42], gi\|110334901\|g...	1.0E-81	[4..435]	[33..468]
gi\|22294708, gi\|... - gi\|22298528\|ref\|NP_681775.1\| hypothetical protein tll0985 [Thermosynechococcus elongatus BP-1], gi\|2...	6.0E-80	[15..445]	[18..446]
gi\|75702703, gi\|... - gi\|75908978\|ref\|YP_323274.1\| hypothetical protein Ava_2766 [Anabaena variabilis ATCC 29413], gi\|7570...	9.0E-80	[14..433]	[17..439]
gi\|145600822, gi... - gi\|145600822\|ref\|YP_001164898.1\| hypothetical protein YPDSF_3575 [Yersinia pestis Pestoides F], gi\|1... gi\|153997303, gi... - gi\|153997303\|ref\|ZP_02022403.1\| putative membrane protein [Yersinia pestis CA88-4125], gi\|149288940\|... gi\|229687236, gi... - gi\|229899744\|ref\|ZP_04514885.1\| predicted inner membrane protein [Yersinia pestis biovar Orientalis ... gi\|229896669, gi... - gi\|229896669\|ref\|ZP_04511836.1\| predicted inner membrane protein [Yersinia pestis Pestoides A], gi\|2... gi\|153948297, gi... - gi\|77631448\|ref\|ZP_00794034.1\| COG1253: Hemolysins and related proteins containing CBS domains [Yers... gi\|165914584, gi... - gi\|89104095\|ref\|ZP_01176649.1\| COG1253: Hemolysins and related proteins containing CBS domains [Yers... gi\|229695546, gi... - gi\|229839180\|ref\|ZP_04459339.1\| predicted inner membrane protein [Yersinia pestis biovar Orientalis ... gi\|25302927 - pir\|\|AG0428 probable membrane protein YPO3526 [imported] - Yersinia pestis (strain CO92) gi\|108777987, gi... - gi\|108806074\|ref\|YP_649990.1\| hypothetical protein YPA_0076 [Yersinia pestis Antiqua], gi\|108777987\|... Q66F90\|Q66F90_YERPS - CorC/HlyC family of putative transporters precursor - Yersinia pseudotuberculosis gi\|229679676, gi... - gi\|229903906\|ref\|ZP_04519019.1\| predicted inner membrane protein [Yersinia pestis Nepal516], gi\|2296... gi\|45440411, gi\|... - gi\|45440411\|ref\|NP_991950.1\| hypothetical protein YP_0557 [Yersinia pestis biovar Microtus str. 9100... gi\|21957372, gi\|... - gi\|22124571\|ref\|NP_667994.1\| hypothetical protein y0657 [Yersinia pestis KIM], gi\|21957372\|gb\|AAM842... gi\|115349151, gi... - gi\|218930540\|ref\|YP_002348415.1\| hypothetical protein YPO3526 [Yersinia pestis CO92], gi\|16123672\|re... gi\|165928160, gi... - gi\|165928160\|ref\|ZP_02223992.1\| CBS/transporter associated domain protein [Yersinia pestis biovar Or... gi\|51594802, gi\|... - gi\|51594802\|ref\|YP_068993.1\| CorC/HlyC family transporters [Yersinia pseudotuberculosis IP 32953], g... gi\|165989730, gi... - gi\|166011346\|ref\|ZP_02232244.1\| CBS/transporter associated domain protein [Yersinia pestis biovar An... gi\|166204776, gi... - gi\|166213981\|ref\|ZP_02240016.1\| CBS/transporter associated domain protein [Yersinia pestis biovar An... gi\|167401337, gi... - gi\|167401337\|ref\|ZP_02306837.1\| CBS/transporter associated domain protein [Yersinia pestis biovar An... gi\|167420785, gi... - gi\|167420785\|ref\|ZP_02312538.1\| CBS/transporter associated domain protein [Yersinia pestis biovar Or... gi\|167057764, gi... - gi\|167423594\|ref\|ZP_02315347.1\| CBS/transporter associated domain protein [Yersinia pestis biovar Me... gi\|170025987, gi... - gi\|170025987\|ref\|YP_001722492.1\| hypothetical protein YPK_3772 [Yersinia pseudotuberculosis YPIII], ... gi\|186893811, gi... - gi\|186893811\|ref\|YP_001870923.1\| hypothetical protein YPTS_0480 [Yersinia pseudotuberculosis PB1/+],...	1.0E-78	[1..446]	[1..443]
gi\|83575009, gi\|... - gi\|83592095\|ref\|YP_425847.1\| hypothetical protein Rru_A0756 [Rhodospirillum rubrum ATCC 11170], gi\|8... gi\|48763001 - ref\|ZP_00267558.1\| COG1253: Hemolysins and related proteins containing CBS domains [Rhodospirillum r...	2.0E-78	[3..431]	[4..433]
gi\|162352242, gi... - gi\|77634768\|ref\|ZP_00796862.1\| COG1253: Hemolysins and related proteins containing CBS domains [Yers...	2.0E-78	[1..446]	[1..443]

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Predicted Domain #1

Region A:
Residues: [1-344]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNSIFIIFC LIAVSAFFSI SEISLAASRK IKLKLLADEG SINAQRVLKM QENPGMFFTV  60
   61 VQIGLNAVAI LGGIVGDAAF SPAFSALFSH YMSPELSEQL SFILSFSLVT GLFILFADLT 120
  121 PKRIGMIAPE AVALRIINPM RFCLFVFRPL VWLFNGMANN IFRLFKIPMV RKDDITSDDI 180
  181 YAVVEAGALA GVLRKQEHEL IENVFELESR TVPSSMTSRE SIIWFDLHED EQSLKKKVAE 240
  241 HPHSKFLVCN EDIDHIIGYV DSKDLLNRVL ANQSMALNSG VQIRNTLIVP DTLTLSEALE 300
  301 SFKTAGEDFA VIMNEYALVV GIITLNDVMT TLMGDLVGQG LEEQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.69897
Match:	2ooxG
Description:	No description for 2ooxG was found.

Predicted Domain #2

Region A:
Residues: [345-447]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVARDENSWL VDGGTPIDDV MRVLDIDEFP QSGNYETIGG FMMFMLRKIP KRTDSVKFSG  60
   61 YKFEVVDIDN YRIDQLLVTR LDNKSNVPAP KLPDAQGKED SAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	14.69897
Match:	2p4pA
Description:	No description for 2p4pA was found.

Predicted functions:

Term	Confidence	Notes
magnesium ion transmembrane transporter activity	4.09048700098247	bayes_pls_golite062009
metal ion transmembrane transporter activity	3.20360029620216	bayes_pls_golite062009
ion transmembrane transporter activity	2.84728629370153	bayes_pls_golite062009
cation transmembrane transporter activity	2.83549234777732	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.62479915553705	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	2.22305253722734	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.09656284183303	bayes_pls_golite062009
transporter activity	1.41639006729672	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	1.21441469552217	bayes_pls_golite062009
transmembrane transporter activity	1.13866512878605	bayes_pls_golite062009
substrate-specific transporter activity	0.917464827903503	bayes_pls_golite062009
binding	0.57037105268889	bayes_pls_golite062009
catalytic activity	0.074501016141151	bayes_pls_golite062009
protein binding	0.0511755694922399	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: