YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|197362644, gi...
Organism:	Salmonella enterica subsp. enterica serovar Paratyphi A str. AKU_12601
Length:	218 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|197362644, gi....

Description	E-value	Query Range	Subject Range
gi\|161485914 - gi\|161485914\|ref\|NP_707345.2\| nicotinamidase/pyrazinamidase [Shigella flexneri 2a str. 301] gi\|161486495 - gi\|161486495\|ref\|NP_837140.2\| nicotinamidase/pyrazinamidase [Shigella flexneri 2a str. 2457T] gi\|110805425, gi... - gi\|110805425\|ref\|YP_688945.1\| nicotinamidase/pyrazinamidase [Shigella flexneri 5 str. 8401], gi\|1106...	2.0E-53	[1..208]	[1..208]
gi\|24051771, gi\|... - gi\|24112835\|ref\|NP_707345.1\| hypothetical protein SF1455 [Shigella flexneri 2a str. 301], gi\|2405177... gi\|30062969, gi\|... - gi\|30062969\|ref\|NP_837140.1\| hypothetical protein S1570 [Shigella flexneri 2a str. 2457T], gi\|300412...	2.0E-53	[1..208]	[7..214]
gi\|75227739 - gi\|75227739\|ref\|ZP_00714471.1\| COG1335: Amidases related to nicotinamidase [Escherichia coli B7A] gi\|81245238, gi\|... - gi\|82543827\|ref\|YP_407774.1\| hypothetical protein SBO_1319 [Shigella boydii Sb227], gi\|81245238\|gb\|A... gi\|75177304 - gi\|75177304\|ref\|ZP_00697393.1\| COG1335: Amidases related to nicotinamidase [Shigella boydii BS512]	3.0E-53	[1..208]	[7..214]
gi\|75190799 - gi\|75190799\|ref\|ZP_00704066.1\| COG1335: Amidases related to nicotinamidase [Escherichia coli E24377A...	6.0E-53	[1..208]	[7..214]
gi\|7429189 - pir\|\|QQECA5 hypothetical 23.4K protein (ansA 3' region) - Escherichia coli (strain K-12) gi\|49176146, gi\|... - gi\|49176146\|ref\|NP_416282.3\| nicotinamidase and pyrazinamidase [Escherichia coli K12], gb\|AAC74838.1... gi\|83586065 - gi\|83586065\|ref\|ZP_00924703.1\| COG1335: Amidases related to nicotinamidase [Escherichia coli 101-1]	2.0E-52	[1..208]	[7..214]
gi\|188487756, gi... - gi\|188492557\|ref\|ZP_02999827.1\| pyrazinamidase/nicotinamidase [Escherichia coli 53638], gi\|188487756... gi\|194422494, gi... - gi\|194438484\|ref\|ZP_03070573.1\| pyrazinamidase/nicotinamidase [Escherichia coli 101-1], gi\|194422494... gi\|254161826, gi... - gi\|254161826\|ref\|YP_003044934.1\| nicotinamidase/pyrazinamidase [Escherichia coli B str. REL606], gi\|... EG11135 - nicotinamidase /pyrazinamidase / Pyrazinamidase /nicotinamidase gi\|169889260, gi... - gi\|170081425\|ref\|YP_001730745.1\| nicotinamidase/pyrazinamidase [Escherichia coli str. K-12 substr. D... EG11135 - nicotinamidase /pyrazinamidase / Pyrazinamidase /nicotinamidase gi\|251785216, gi... - gi\|251785216\|ref\|YP_002999520.1\| hypothetical protein B21_01725 [Escherichia coli BL21], gi\|24237748... gi\|253324321, gi... - gi\|254288614\|ref\|YP_003054362.1\| nicotinamidase/pyrazinamidase [Escherichia coli BL21(DE3)], gi\|2539... PNCA_ECOLI - Pyrazinamidase/nicotinamidase (EC 3.5.1.-) (EC 3.5.1.19) (PZAase) (Nicotine deamidase) (NAMase) - Es... gi\|89108607, gi\|... - gi\|89108607\|ref\|AP_002387.1\| nicotinamidase/pyrazinamidase [Escherichia coli str. K-12 substr. W3110... gi\|157066910, gi... - gi\|157161230\|ref\|YP_001458548.1\| nicotinamidase/pyrazinamidase [Escherichia coli HS], gi\|157066910\|g... gi\|238861893, gi... - gi\|238900982\|ref\|YP_002926778.1\| nicotinamidase/pyrazinamidase [Escherichia coli BW2952], gi\|2388618...	2.0E-52	[1..208]	[1..208]
gi\|73855391, gi\|... - gi\|74311914\|ref\|YP_310333.1\| hypothetical protein SSON_1387 [Shigella sonnei Ss046], gi\|73855391\|gb\|...	2.0E-52	[1..208]	[7..214]
gi\|81240933, gi\|... - gi\|82776785\|ref\|YP_403134.1\| hypothetical protein SDY_1505 [Shigella dysenteriae Sd197], gi\|81240933...	2.0E-52	[1..208]	[7..214]
gi\|75513736 - gi\|75513736\|ref\|ZP_00736112.1\| COG1335: Amidases related to nicotinamidase [Escherichia coli 53638] gi\|75195836 - gi\|75195836\|ref\|ZP_00705906.1\| COG1335: Amidases related to nicotinamidase [Escherichia coli HS]	2.0E-52	[1..208]	[7..214]
gi\|13361942, gi\|... - gi\|15831729\|ref\|NP_310502.1\| hypothetical protein ECs2475 [Escherichia coli O157:H7], gi\|13361942\|db... gi\|209768360, gi... - pir\|\|G85786 hypothetical protein ydjB [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|12515794, gi\|... - gi\|15802180\|ref\|NP_288202.1\| hypothetical protein Z2802 [Escherichia coli O157:H7 EDL933], gi\|125157... gi\|13361942, gi\|... - gi\|15831729\|ref\|NP_310502.1\| hypothetical protein ECs2475 [Escherichia coli O157:H7 str. Sakai], gi\|...	2.0E-52	[1..208]	[7..214]

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Predicted Domain #1

Region A:
Residues: [1-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNRALLLVD LQNDFCAGGA LAVAEGDSTI DIANALIDWC QPRQIPVLAS QDWHPAQHGS  60
   61 FASQHQAEPY RQGKLDGLPQ TLWPDHCVQH TDGAALHPLL NQHAIDACIY KGENPLIDSY 120
  121 SAFFDNEHRQ KTTLDTWLRE HDVTELIVMG LATDYCVKFT VLDALELGYA VNVITDGCRG 180
  181 VNIHPQDSAH AFMEMAAAGA TLYTLADWEE TQGQAIAR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.221849
Match:	1ilwA
Description:	Pyrazinamidase/nicotinamidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinamidase activity	2.590271821288	bayes_pls_golite062009
binding	1.80707112356899	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1.33901087189475	bayes_pls_golite062009
catalytic activity	0.992051062697807	bayes_pls_golite062009
protein binding	0.343971697425971	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: