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View Structure Prediction Details

Protein: gi|190405404
Organism: Saccharomyces cerevisiae RM11-1a
Length: 482 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190405404.

Description E-value Query
Range		 Subject
Range
gi|151940882 - gi|151940882|gb|EDN59264.1| adenylosuccinate lyase [Saccharomyces cerevisiae YJM789]
ADE13 - Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway;...
PUR8_YEAST - Adenylosuccinate lyase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADE13 PE=1 SV=1
gi|190405404 - gi|190405404|gb|EDV08671.1| adenylosuccinate lyase [Saccharomyces cerevisiae RM11-1a]
 0.0 [1..482] [1..482]
gi|3983439 - gi|3983439|gb|AAC83935.1| adenylosuccinate lyase [Homo sapiens]
 0.0 [3..476] [9..479]
PUR8_MOUSE - Adenylosuccinate lyase OS=Mus musculus GN=Adsl PE=1 SV=2
 0.0 [3..476] [9..479]
gi|15054368 - gi|15054368|gb|AAK61418.1| adenylosuccinate lyase [Pichia angusta]
 0.0 [3..482] [16..495]
PUR8_SCHPO - Adenylosuccinate lyase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ade8 PE=3 SV=1
ade8 - adenylosuccinate lyase Ade8
 0.0 [1..482] [1..482]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [20..476] [1..454]
ARLY2_ANAPL - Argininosuccinate lyase OS=Anas platyrhynchos GN=ASL2 PE=1 SV=4
 0.0 [1..472] [1..467]

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Predicted Domain #1
Region A:
Residues: [1-115] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDYDNYTTP LSSRYASKEM SATFSLRNRF STWRKLWLNL AIAEKELGLT VVTDEAIEQM  60
   61 RKHVEITDDE IAKASAQEAI VRHDVMAHVH TFGETCPAAA GIIHLGATSC FVTDN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [190-240] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGLRGVKGTT GTQASFLALF HGNHDKVEAL DERVTELLGF DKVYPVTGQT Y

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 519.228787
Match: 1f1oA_
Description: Adenylosuccinate lyase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [116-130] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADLIFIRDAY DIIIP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [175-189] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELLWDLRNFE RARND

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [241-258] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRKIDIDVLA PLSSFAAT

[Run NCBI BLAST on this sequence.]

Region D:
Residues: [297-345] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RCERVCSLAR HLGSLFSDAV QTASVQWFER TLDDSAIRRI SLPSAFLTA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 519.228787
Match: 1f1oA_
Description: Adenylosuccinate lyase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [131-174] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLVNVINRLA KFAMEYKDLP VLGWTHFQPA QLTTLGKRAT LWIQ

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [259-296] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHKMATDIRL LANLKEVEEP FEKSQIGSSA MAYKRNPM

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [346-482] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DILLSTLLNI SSGLVVYPKV IERRIKGELP FMATENIIMA MVEKNASRQE VHERIRVLSH  60
   61 QAAAVVKEEG GENDLIERVK RDEFFKPIWE ELDSLLEPST FVGRAPQQVE KFVQKDVNNA 120
  121 LQPFQKYLND EQVKLNV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 519.228787
Match: 1f1oA_
Description: Adenylosuccinate lyase
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle