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View Structure Prediction Details

Protein: gi|207347342
Organism: Saccharomyces cerevisiae AWRI1631
Length: 521 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|207347342.

Description E-value Query
Range
Subject
Range
PGPS1_YEAST - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase OS=Saccharomyces cerevisiae (stra...
gi|207347342 - gi|207347342|gb|EDZ73542.1| YCL004Wp-like protein [Saccharomyces cerevisiae AWRI1631]
PGS1 - Phosphatidylglycerolphosphate synthase, catalyzes the synthesis of phosphatidylglycerolphosphate fro...
0.0 [1..521] [1..521]
PGPS1_SACPS - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase OS=Saccharomyces pastorianus GN=P...
0.0 [1..521] [1..521]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [30..507] [1..482]
gi|19386924 - gi|19386924|gb|AAL87040.1|AF411101_1 silencer-associated factor [Mus musculus]
0.0 [51..520] [41..512]
PGPS1_CRIGR - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial OS=Cricetulus gris...
0.0 [51..520] [81..552]
gi|220948928, gi... - gi|220957696|gb|ACL91391.1| CG7718-PA [synthetic construct], gi|220948928|gb|ACL87007.1| CG7718-PA [...
CG7718-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7718 (CG7718, FBgn0038649). It is a protein...
1.0E-88 [51..520] [49..493]
SPBP18G5.02 - CDP-diacylglycerol-glycerol-3-phosphate3-phosphatidyltransferase
PGPS1_SCHPO - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase OS=Schizosaccharomyces pombe (str...
1.0E-87 [45..521] [9..534]

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Predicted Domain #1
Region A:
Residues: [1-68]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTRLLQLTR PHYRLLSLPL QKPFNIKRQM SAANPSPFGN YLNTITKSLQ QNLQTCFHFQ  60
   61 AKEIDIIE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.596 0.271 phospholipid biosynthetic process a.4.1 Homeodomain-like
View Download 0.609 0.037 phospholipid biosynthetic process a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.578 0.021 phospholipid biosynthetic process a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.610 0.007 phospholipid biosynthetic process a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.610 N/A N/A a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.609 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.596 N/A N/A a.4.1 Homeodomain-like
View Download 0.592 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.592 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.578 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.546 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.540 N/A N/A a.64.1 Saposin
View Download 0.508 N/A N/A a.4.8 Ribosomal protein S18
View Download 0.493 N/A N/A a.101.1 Uteroglobin-like
View Download 0.470 N/A N/A a.112.1 Description not found.
View Download 0.462 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.437 N/A N/A a.64.1 Saposin
View Download 0.418 N/A N/A a.4.12 TrpR-like
View Download 0.391 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.386 N/A N/A a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.380 N/A N/A a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.368 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.356 N/A N/A a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.355 N/A N/A a.157.1 Skp1 dimerisation domain-like
View Download 0.351 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.347 N/A N/A a.2.7 tRNA-binding arm
View Download 0.337 N/A N/A a.4.1 Homeodomain-like
View Download 0.331 N/A N/A a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.330 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.328 N/A N/A a.101.1 Uteroglobin-like
View Download 0.314 N/A N/A d.6.1 Prion-like
View Download 0.304 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.299 N/A N/A a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.298 N/A N/A a.4.1 Homeodomain-like
View Download 0.296 N/A N/A a.112.1 Description not found.
View Download 0.291 N/A N/A a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.277 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.275 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.273 N/A N/A a.2.3 Chaperone J-domain
View Download 0.272 N/A N/A a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.253 N/A N/A a.46.1 Methionine synthase domain
View Download 0.252 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.249 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.246 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.244 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.242 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.242 N/A N/A a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.240 N/A N/A a.30.1 ROP protein
View Download 0.240 N/A N/A a.4.12 TrpR-like
View Download 0.239 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.234 N/A N/A a.77.1 DEATH domain
View Download 0.231 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.231 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.230 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.224 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.223 N/A N/A a.144.2 Ribosomal protein L20
View Download 0.223 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.218 N/A N/A a.77.1 DEATH domain
View Download 0.217 N/A N/A a.4.8 Ribosomal protein S18
View Download 0.215 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.212 N/A N/A d.58.49 YajQ-like
View Download 0.208 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.208 N/A N/A a.126.1 Serum albumin-like
View Download 0.206 N/A N/A a.3.1 Cytochrome c
View Download 0.205 N/A N/A a.157.1 Skp1 dimerisation domain-like
View Download 0.201 N/A N/A f.17.1 F1F0 ATP synthase subunit C
View Download 0.201 N/A N/A d.52.3 Prokaryotic type KH domain (KH-domain type II)

Predicted Domain #2
Region A:
Residues: [69-521]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPSQFYDLLK TKILNSQNRI FIASLYLGKS ETELVDCISQ ALTKNPKLKV SFLLDGLRGT  60
   61 RELPSACSAT LLSSLVAKYG SERVDCRLYK TPAYHGWKKV LVPKRFNEGL GLQHMKIYGF 120
  121 DNEVILSGAN LSNDYFTNRQ DRYYLFKSRN FSNYYFKLHQ LISSFSYQII KPMVDGSINI 180
  181 IWPDSNPTVE PTKNKRLFLR EASQLLDGFL KSSKQSLPIT AVGQFSTLVY PISQFTPLFP 240
  241 KYNDKSTEKR TILSLLSTIT SNAISWTFTA GYFNILPDIK AKLLATPVAE ANVITASPFA 300
  301 NGFYQSKGVS SNLPGAYLYL SKKFLQDVCR YRQDHAITLR EWQRGVVNKP NGWSYHAKGI 360
  361 WLSARDKNDA NNWKPFITVI GSSNYTRRAY SLDLESNALI ITRDEELRKK MKAELDNLLQ 420
  421 YTKPVTLEDF QSDPERHVGT GVKIATSILG KKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.221849
Match: 1f0iA_
Description: Phospholipase D
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.42274246180183 bayes_pls_golite062009
catalytic activity 1.29236214516383 bayes_pls_golite062009
phosphoric diester hydrolase activity 1.25148072945538 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.97354820978871 bayes_pls_golite062009
nucleic acid binding 0.566950403258922 bayes_pls_golite062009
protein binding 0.438178121330569 bayes_pls_golite062009
transferase activity 0.417847571627092 bayes_pls_golite062009
kinase activity 0.41582825017763 bayes_pls_golite062009
DNA binding 0.402372477477629 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.398900256450913 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle