YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213052176
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E00-7866
Length:	300 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213052176.

Description	E-value	Query Range	Subject Range
gi\|82778934, gi\|... - gi\|82778934\|ref\|YP_405283.1\| formate dehydrogenase-O, iron-sulfur subunit [Shigella dysenteriae Sd19...	3.0E-73	[1..300]	[1..300]
gi\|218363225, gi... - gi\|218556456\|ref\|YP_002389370.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli IAI1], gi\|2... gi\|209914629, gi... - gi\|209921370\|ref\|YP_002295454.1\| formate dehydrogenase iron-sulfur subunit [Escherichia coli SE11], ... gi\|218692181, gi... - gi\|218692181\|ref\|YP_002400393.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli ED1a], gi\|2... gi\|218367735, gi... - gi\|218560966\|ref\|YP_002393879.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli S88], gi\|21... gi\|218701406, gi... - gi\|218701406\|ref\|YP_002409035.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli IAI39], gi\|... gi\|218354340, gi... - gi\|218697608\|ref\|YP_002405275.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli 55989], gi\|... gi\|218707522, gi... - gi\|218707522\|ref\|YP_002415041.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli UMN026], gi... FDOH_SHIFL - Formate dehydrogenase-O iron-sulfur subunit OS=Shigella flexneri GN=fdoH PE=3 SV=1 gi\|24054468, gi\|... - gi\|24115187\|ref\|NP_709697.1\| formate dehydrogenase-O, iron-sulfur subunit [Shigella flexneri 2a str.... FDOH_ECOL6 - Formate dehydrogenase-O iron-sulfur subunit OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 /... gi\|30043074, gi\|... - gi\|30064814\|ref\|NP_838985.1\| formate dehydrogenase-O, iron-sulfur subunit [Shigella flexneri 2a str.... EG11857 - formate dehydrogenase-O, Fe-S subunit / Formate dehydrogenase-O Fe-S subunit, aerobic FDOH_ECOLI - Formate dehydrogenase-O, iron-sulfur subunit (Formate dehydrogenase-O subunit beta) (FDH-Z subunit b... gi\|73857872, gi\|... - gi\|74314395\|ref\|YP_312814.1\| formate dehydrogenase-O, iron-sulfur subunit [Shigella sonnei Ss046], g... gi\|81247650, gi\|... - gi\|82546239\|ref\|YP_410186.1\| formate dehydrogenase-O, iron-sulfur subunit [Shigella boydii Sb227], g... gi\|192929415, gi... - gi\|75258124\|ref\|ZP_00729585.1\| COG0437: Fe-S-cluster-containing hydrogenase components 1 [Escherichi... gi\|75513960, gi\|... - gi\|75513960\|ref\|ZP_00736313.1\| COG0437: Fe-S-cluster-containing hydrogenase components 1 [Escherichi... gi\|115515287, gi... - gi\|117626163\|ref\|YP_859486.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli APEC O1], gi\|1... gi\|124501256, gi... - gi\|124527554\|ref\|ZP_01699019.1\| formate dehydrogenase, beta subunit [Escherichia coli B], gi\|1245012... gi\|85676166, gi\|... - gi\|89110135\|ref\|AP_003915.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli str. K-12 subst... gi\|187429405, gi... - gi\|75176720\|ref\|ZP_00696848.1\| COG0437: Fe-S-cluster-containing hydrogenase components 1 [Shigella b... gi\|157155894, gi... - gi\|75188628\|ref\|ZP_00701895.1\| COG0437: Fe-S-cluster-containing hydrogenase components 1 [Escherichi... gi\|91075011, gi\|... - gi\|91213437\|ref\|YP_543423.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli UTI89], ... gi\|110644234, gi... - gi\|110644234\|ref\|YP_671964.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli 536], g... gi\|83586260, gi\|... - gi\|83586260\|ref\|ZP_00924896.1\| COG0437: Fe-S-cluster-containing hydrogenase components 1 [Escherichi... gi\|110807417, gi... - gi\|110807417\|ref\|YP_690937.1\| formate dehydrogenase-O, iron-sulfur subunit [Shigella flexneri 5 str.... gi\|75237856, gi\|... - gi\|75237856\|ref\|ZP_00721871.1\| COG0437: Fe-S-cluster-containing hydrogenase components 1 [Escherichi... gi\|75238336, gi\|... - gi\|75238336\|ref\|ZP_00722335.1\| COG0437: Fe-S-cluster-containing hydrogenase components 1 [Escherichi... gi\|75197765, gi\|... - gi\|75197765\|ref\|ZP_00707835.1\| COG0437: Fe-S-cluster-containing hydrogenase components 1 [Escherichi... gi\|190903562, gi... - gi\|75230414\|ref\|ZP_00716900.1\| COG0437: Fe-S-cluster-containing hydrogenase components 1 [Escherichi... gi\|227885367, gi... - gi\|227885367\|ref\|ZP_04003172.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli 83972], gi\|2... gi\|226902862, gi... - gi\|237702925\|ref\|ZP_04533406.1\| formate dehydrogenase-O beta subunit [Escherichia sp. 3_2_53FAA], gi... gi\|238861134, gi... - gi\|238902960\|ref\|YP_002928756.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli BW2952], gi... gi\|251787157, gi... - gi\|251787157\|ref\|YP_003001461.1\| hypothetical protein B21_03727 [Escherichia coli BL21], gi\|24237943... gi\|253326513, gi... - gi\|254290594\|ref\|YP_003056342.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli BL21(DE3)],... gi\|226838540, gi... - gi\|254039104\|ref\|ZP_04873154.1\| formate dehydrogenase-O [Escherichia sp. 1_1_43], gi\|226838540\|gb\|EE... gi\|170022095, gi... - gi\|170022095\|ref\|YP_001727049.1\| formate dehydrogenase, beta subunit [Escherichia coli ATCC 8739], g... EG11857 - formate dehydrogenase-O, Fe-S subunit / Formate dehydrogenase-O Fe-S subunit, aerobic gi\|253975744, gi... - gi\|254163843\|ref\|YP_003046951.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli B str. REL6... FDOH_ECOL6 - Formate dehydrogenase-O iron-sulfur subunit OS=Escherichia coli O6 GN=fdoH PE=3 SV=1 gi\|170680015, gi... - gi\|170680015\|ref\|YP_001746224.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli SMS-... gi\|170083365, gi... - gi\|170083365\|ref\|YP_001732685.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli str. K-12 s...	4.0E-73	[1..300]	[1..300]
gi\|83569843, gi\|... - gi\|83569843\|ref\|ZP_00921292.1\| COG0437: Fe-S-cluster-containing hydrogenase components 1 [Shigella d...	4.0E-73	[1..300]	[1..300]
gi\|194414507, gi... - gi\|75211293\|ref\|ZP_00711392.1\| COG0437: Fe-S-cluster-containing hydrogenase components 1 [Escherichi...	5.0E-73	[1..300]	[1..300]
gi\|37528694, gi\|... - gi\|37528694\|ref\|NP_932039.1\| formate dehydrogenase-O, iron-sulfur subunit (formate dehydrogenase-O b...	1.0E-72	[1..297]	[1..297]
gi\|189001488, gi... - gi\|189001488\|gb\|EDU70474.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:H7 s... gi\|168786742, gi... - gi\|189373333\|gb\|EDU91749.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:H7 s... gi\|209752562, gi... - pir\|\|C91231 formate dehydrogenase-O iron-sulfur subunit [imported] - Escherichia coli (strain O157:H... gi\|189378011, gi... - gi\|189378011\|gb\|EDU96427.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:H7 s... gi\|13364295, gi\|... - gi\|15834073\|ref\|NP_312846.1\| formate dehydrogenase-O iron-sulfur subunit [Escherichia coli O157:H7],... gi\|195937533 - gi\|195937533\|ref\|ZP_03082915.1\| formate dehydrogenase-O iron-sulfur subunit [Escherichia coli O157:H... gi\|168755571, gi... - gi\|189357170\|gb\|EDU75589.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:H7 s... gi\|168761730, gi... - gi\|189367938\|gb\|EDU86354.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:H7 s... gi\|189362637, gi... - gi\|189362637\|gb\|EDU81056.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:H7 s... gi\|187769120, gi... - gi\|187769120\|gb\|EDU32964.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:H7 s... gi\|188016796, gi... - gi\|188016796\|gb\|EDU54918.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:H7 s... gi\|254795888, gi... - gi\|254795888\|ref\|YP_003080725.1\| formate dehydrogenase-O, Fe-S subunit [Escherichia coli O157:H7 str... gi\|13364295, gi\|... - gi\|15834073\|ref\|NP_312846.1\| formate dehydrogenase-O iron-sulfur subunit [Escherichia coli O157:H7 s... gi\|217320883, gi... - gi\|217324662\|ref\|ZP_03440746.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:... gi\|208808903, gi... - gi\|208808903\|ref\|ZP_03251240.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:... gi\|208735217, gi... - gi\|208813940\|ref\|ZP_03255269.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:... gi\|208818459, gi... - gi\|208818459\|ref\|ZP_03258779.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:... gi\|209160203, gi... - gi\|209398803\|ref\|YP_002273410.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157...	3.0E-72	[1..300]	[1..300]
gi\|25285347 - pir\|\|B86078 formate dehydrogenase-O, iron-sulfur subunit [imported] - Escherichia coli (strain O157:... gi\|12518785, gi\|... - gi\|15804482\|ref\|NP_290522.1\| formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:H7 ...	3.0E-71	[1..300]	[1..300]
gi\|197364811, gi... - gi\|197364811\|ref\|YP_002144448.1\| formate dehydrogenase-O beta subunit [Salmonella enterica subsp. en... gi\|56415882, gi\|... - gi\|56415882\|ref\|YP_152957.1\| formate dehydrogenase-O beta subunit [Salmonella enterica subsp. enteri...	2.0E-69	[1..300]	[1..300]
gi\|238912180 - gi\|238912180\|ref\|ZP_04656017.1\| formate dehydrogenase-O, iron-sulfur subunit [Salmonella enterica su... gi\|16422599, gi\|... - gi\|16767301\|ref\|NP_462916.1\| formate dehydrogenase-O beta subunit [Salmonella typhimurium LT2], gi\|1... gi\|197240000, gi... - gi\|197261745\|ref\|ZP_03161819.1\| formate dehydrogenase-O, iron-sulfur subunit [Salmonella enterica su... gi\|204320614, gi... - gi\|204930210\|ref\|ZP_03221187.1\| formate dehydrogenase-O, iron-sulfur subunit [Salmonella enterica su... gi\|205341794, gi... - gi\|205341794\|gb\|EDZ28558.1\| formate dehydrogenase-O, iron-sulfur subunit [Salmonella enterica subsp.... gi\|194451151, gi... - gi\|194451151\|ref\|YP_002048037.1\| formate dehydrogenase-O, iron-sulfur subunit [Salmonella enterica s... gi\|168244219, gi... - gi\|205336904\|gb\|EDZ23668.1\| formate dehydrogenase-O, iron-sulfur subunit [Salmonella enterica subsp.... gi\|168467369, gi... - gi\|195630226\|gb\|EDX48866.1\| formate dehydrogenase-O, iron-sulfur subunit [Salmonella enterica subsp.... lcl\|NC_016856.1_... - [gene=fdoH] [protein=formate dehydrogenase-O beta subunit] [protein_id=YP_005240304.1] [location=com... gi\|167991561, gi... - gi\|205329943\|gb\|EDZ16707.1\| formate dehydrogenase-O, iron-sulfur subunit [Salmonella enterica subsp....	4.0E-69	[1..300]	[1..300]
gi\|62130129, gi\|... - gi\|62182496\|ref\|YP_218913.1\| formate dehydrogenase-O, Fe-S subunit [Salmonella enterica subsp. enter...	2.0E-68	[1..300]	[1..300]

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Predicted Domain #1

Region A:
Residues: [1-300]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYQSQDIIR RSATNGFTPA PQARDHQEEV AKLIDVTTCI GCKACQVACS EWNDIRDEVG  60
   61 NNVGVYDNPA DLTAKSWTVM RFSEVEQNDK LEWLIRKDGC MHCADPGCLK ACPAEGAIIQ 120
  121 YANGIVDFQS EQCIGCGYCI AGCPFNVPRL NPEDNRVYKC TLCVDCVVVG QEPACVKTCP 180
  181 TGAIHFGSKE DMKTLAGERV AELKTRGYDN AGLYDPAGVG GTHVMYVLHH ADKPNLYHGL 240
  241 PENPEISETV KFWKGVWKPL AAFGFAATFA ASVFHYVGVG PNRAEEEDDN LHEEKDEVRK 300
  301

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	69.69897
Match:	1kqfB
Description:	Formate dehydrogenase N, iron-sulfur (beta) subunit; Iron-sulfur subunit of formate dehydrogenase N, transmembrane anchor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
formate dehydrogenase activity	10.9674358961972	bayes_pls_golite062009
oxidoreductase activity	5.98361135786786	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	5.77927347135001	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	5.39747453448396	bayes_pls_golite062009
electron carrier activity	5.05393703018095	bayes_pls_golite062009
NADH dehydrogenase activity	3.13953145151561	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	2.76338281383262	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	2.70037803782769	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	2.09041948600744	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	1.80621486978907	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	1.5619384041388	bayes_pls_golite062009
iron-sulfur cluster binding	1.30496569995148	bayes_pls_golite062009
metal cluster binding	1.30496569995148	bayes_pls_golite062009
catalytic activity	0.488483980994331	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: