YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|168466561, gi...
Organism:	Salmonella enterica subsp. enterica serovar Newport str. SL317
Length:	760 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|168466561, gi....

Description	E-value	Query Range	Subject Range
gi\|75229892, gi\|... - gi\|75229892\|ref\|ZP_00716415.1\| COG1882: Pyruvate-formate lyase [Escherichia coli B7A], gi\|191166987\|...	0.0	[1..760]	[1..760]
PFLB_ECOLI - Formate acetyltransferase 1 (EC 2.3.1.54) (Pyruvate formate-lyase 1) - Escherichia coli EG10701 - formate C-acetyltransferase 1, anaerobic; pyruvate formate-lyase 1 / Formate C-acetyltransferase 1; ... gi\|218364577, gi... - gi\|218557808\|ref\|YP_002390721.1\| pyruvate formate lyase I [Escherichia coli S88], gi\|218364577\|emb\|C... gi\|218553489, gi... - gi\|218553489\|ref\|YP_002386402.1\| pyruvate formate lyase I [Escherichia coli IAI1], gi\|218360257\|emb\|... gi\|218426307, gi... - gi\|218688743\|ref\|YP_002396955.1\| pyruvate formate lyase I [Escherichia coli ED1a], gi\|218426307\|emb\|... gi\|75512059, gi\|... - gi\|75512059\|ref\|ZP_00734644.1\| COG1882: Pyruvate-formate lyase [Escherichia coli 53638], gi\|18849291... gi\|73854936, gi\|... - gi\|74311459\|ref\|YP_309878.1\| formate acetyltransferase 1 [Shigella sonnei Ss046], gi\|73854936\|gb\|AAZ... gi\|191172132, gi... - gi\|75240977\|ref\|ZP_00724866.1\| COG1882: Pyruvate-formate lyase [Escherichia coli F11], gi\|191172132\|... gi\|192927747, gi... - gi\|75257382\|ref\|ZP_00728898.1\| COG1882: Pyruvate-formate lyase [Escherichia coli E22], gi\|193064690\|... gi\|117623121, gi... - gi\|117623121\|ref\|YP_852034.1\| PflB [Escherichia coli APEC O1], gi\|115512245\|gb\|ABJ00320.1\| PflB [Esc... gi\|124531972, gi... - gi\|124531972\|ref\|ZP_01702031.1\| formate acetyltransferase [Escherichia coli B], gi\|124498234\|gb\|EAY4... gi\|157160425, gi... - gi\|75195091\|ref\|ZP_00705161.1\| COG1882: Pyruvate-formate lyase [Escherichia coli HS], gi\|157160425\|r... gi\|194413580, gi... - gi\|75210408\|ref\|ZP_00710564.1\| COG1882: Pyruvate-formate lyase [Escherichia coli B171], gi\|194428365... gi\|194438693, gi... - gi\|83585846\|ref\|ZP_00924486.1\| COG1882: Pyruvate-formate lyase [Escherichia coli 101-1], gi\|19443869... gi\|75189958, gi\|... - gi\|75189958\|ref\|ZP_00703225.1\| COG1882: Pyruvate-formate lyase [Escherichia coli E24377A], gi\|157157... gi\|89107753, gi\|... - gi\|89107753\|ref\|AP_001533.1\| pyruvate formate lyase I [Escherichia coli str. K-12 substr. W3110], gi... gi\|91071578, gi\|... - gi\|91210004\|ref\|YP_539990.1\| formate acetyltransferase 1 [Escherichia coli UTI89], gi\|91071578\|gb\|AB... EG10701 - formate C-acetyltransferase 1, anaerobic; pyruvate formate-lyase 1 / Formate C-acetyltransferase 1; ... gi\|110641100, gi... - gi\|110641100\|ref\|YP_668830.1\| formate acetyltransferase 1 [Escherichia coli 536], gi\|110342692\|gb\|AB... gi\|227838884, gi... - gi\|227884132\|ref\|ZP_04001937.1\| pyruvate formate lyase I [Escherichia coli 83972], gi\|227838884\|gb\|E... gi\|237707109, gi... - gi\|237707109\|ref\|ZP_04537590.1\| formate acetyltransferase 1 [Escherichia sp. 3_2_53FAA], gi\|22689831... gi\|238900161, gi... - gi\|238900161\|ref\|YP_002925957.1\| pyruvate formate lyase I [Escherichia coli BW2952], gi\|238863359\|gb... gi\|169888396, gi... - gi\|170080561\|ref\|YP_001729881.1\| pyruvate formate lyase I [Escherichia coli str. K-12 substr. DH10B]... gi\|242376718, gi... - gi\|251784445\|ref\|YP_002998749.1\| hypothetical protein B21_00914 [Escherichia coli BL21], gi\|24237671... gi\|169755623, gi... - gi\|170020695\|ref\|YP_001725649.1\| formate acetyltransferase [Escherichia coli ATCC 8739], gi\|16975562... gi\|253977132, gi... - gi\|254287825\|ref\|YP_003053573.1\| pyruvate formate lyase I [Escherichia coli BL21(DE3)], gi\|253977132... gi\|253972918, gi... - gi\|254161017\|ref\|YP_003044125.1\| pyruvate formate lyase I [Escherichia coli B str. REL606], gi\|25397...	0.0	[1..760]	[1..760]
gi\|187430216, gi... - gi\|75178294\|ref\|ZP_00698348.1\| COG1882: Pyruvate-formate lyase [Shigella boydii BS512], gi\|187733224... gi\|81246052, gi\|... - gi\|82544641\|ref\|YP_408588.1\| formate acetyltransferase 1 [Shigella boydii Sb227], gi\|81246052\|gb\|ABB... gi\|215264100, gi... - gi\|215486028\|ref\|YP_002328459.1\| pyruvate formate lyase I [Escherichia coli O127:H6 str. E2348/69], ...	0.0	[1..760]	[1..760]
gi\|24112311, gi\|... - gi\|24112311\|ref\|NP_706821.1\| formate acetyltransferase 1 [Shigella flexneri 2a str. 301], gi\|2405116... gi\|110804911, gi... - gi\|110804911\|ref\|YP_688431.1\| formate acetyltransferase 1 [Shigella flexneri 5 str. 8401], gi\|110614... gi\|30040684, gi\|... - gi\|30062438\|ref\|NP_836609.1\| formate acetyltransferase 1 [Shigella flexneri 2a str. 2457T], gi\|30040...	0.0	[1..760]	[1..760]
PFLB_ECOLI - (P09373) Formate acetyltransferase 1 (EC 2.3.1.54) (Pyruvate formate-lyase 1)	0.0	[2..760]	[1..759]
gi\|75234414, gi\|... - gi\|75234414\|ref\|ZP_00718775.1\| COG1882: Pyruvate-formate lyase [Escherichia coli E110019], gi\|193070...	0.0	[1..760]	[1..760]
gi\|25285928, gi\|... - pir\|\|H85615 formate acetyltransferase 1 [imported] - Escherichia coli (strain O157:H7, substrain ED... gi\|254792102, gi... - gi\|254792102\|ref\|YP_003076939.1\| pyruvate formate lyase I [Escherichia coli O157:H7 str. TW14359], g... gi\|12514066, gi\|... - gi\|15800764\|ref\|NP_286778.1\| formate acetyltransferase 1 [Escherichia coli O157:H7 EDL933], gi\|12514... gi\|13360445, gi\|... - gi\|15830240\|ref\|NP_309013.1\| formate acetyltransferase 1 [Escherichia coli O157:H7], gi\|13360445\|dbj... gi\|217324930, gi... - gi\|217324930\|ref\|ZP_03441014.1\| formate acetyltransferase [Escherichia coli O157:H7 str. TW14588], g... gi\|209399377, gi... - gi\|209399377\|ref\|YP_002269575.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4115], g... gi\|218370565, gi... - gi\|218700579\|ref\|YP_002408208.1\| pyruvate formate lyase I [Escherichia coli IAI39], gi\|218370565\|emb... gi\|218694376, gi... - gi\|218694376\|ref\|YP_002402043.1\| pyruvate formate lyase I [Escherichia coli 55989], gi\|218351108\|emb... gi\|195939564 - gi\|195939564\|ref\|ZP_03084946.1\| formate acetyltransferase 1 [Escherichia coli O157:H7 str. EC4024] gi\|170681780, gi... - gi\|170681780\|ref\|YP_001744268.1\| formate acetyltransferase [Escherichia coli SMS-3-5], gi\|170519498\|... gi\|208737573, gi... - gi\|208822088\|ref\|ZP_03262407.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4042], gi... gi\|208732552, gi... - gi\|208815904\|ref\|ZP_03257083.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4045], gi... gi\|168783814, gi... - gi\|188998916\|gb\|EDU67902.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4076], gi\|168... gi\|187768347, gi... - gi\|187768347\|gb\|EDU32191.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4196], gi\|168... gi\|189376449, gi... - gi\|189376449\|gb\|EDU94865.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC508], gi\|1688... gi\|189372706, gi... - gi\|189372706\|gb\|EDU91122.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC869], gi\|1687... gi\|189355903, gi... - gi\|189355903\|gb\|EDU74322.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4401], gi\|168... gi\|168752114, gi... - gi\|188013955\|gb\|EDU52077.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4113], gi\|168... gi\|13360445, gi\|... - gi\|15830240\|ref\|NP_309013.1\| formate acetyltransferase 1 [Escherichia coli O157:H7 str. Sakai], gi\|1... gi\|189361112, gi... - gi\|189361112\|gb\|EDU79531.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4486], gi\|168... gi\|81241725, gi\|... - gi\|82777577\|ref\|YP_403926.1\| formate acetyltransferase 1 [Shigella dysenteriae Sd197], gi\|81241725\|g... gi\|168762962, gi... - gi\|189366827\|gb\|EDU85243.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4501], gi\|168...	0.0	[1..760]	[1..760]
gi\|83569142, gi\|... - gi\|83569142\|ref\|ZP_00920601.1\| COG1882: Pyruvate-formate lyase [Shigella dysenteriae 1012], gi\|19443...	0.0	[1..760]	[1..760]
gi\|62127130, gi\|... - gi\|62179497\|ref\|YP_215914.1\| pyruvate formate lyase I, induced anaerobically [Salmonella enterica su...	0.0	[1..760]	[1..760]

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Predicted Domain #1

Region A:
Residues: [1-760]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELNEKLAT AWEGFTKGDW QNEVNVRDFI QKNYTPYEGD ESFLAGATDA TTKLWDSVME  60
   61 GVKQENRTHA PVDFDTSVAS TITSHDAGYI NKALEKIVGL QTEAPLKRAI IPFGGIKMVE 120
  121 GSCKAYNREL DPMIKKIFTE YRKTHNQGVF DVYTPDILRC RKSGVLTGLP DAYGRGRIIG 180
  181 DYRRVALYGI DYLMKDKFAQ FTSLQSDLEN GVNLEATIRL REEIAEQHRA LGQIKEMAAK 240
  241 YGCDISGPAT NAQEAIQWTY FGYLAAVKSQ NGAAMSFGRV STFLDAYIER DLKAGKITEQ 300
  301 DAQEMIDHLV MKLRMVRFLR TPEYDELFSG DPIWATESIG GMGVDGRTLV TKNSFRFLNT 360
  361 LYTMGPSPEP NITVLWSEKL PLNFKKFAAK VSIDTSSLQY ENDDLMRPDF NNDDYAIACC 420
  421 VSPMIVGKQM QFFGARANLA KTMLYAINGG VDEKLKMQVG PKSEPIKGDV LNFDEVMDRM 480
  481 DHFMDWLAKQ YVTALNVIHY MHDKYSYEAS LMALHDRDVI RTMACGIAGL SVAADSLSAI 540
  541 KYAKVKPIRD EDGLAIDFEI EGEYPQFGNN DARVDDMAVD LVERFMKKIQ KLTTYRGAIP 600
  601 TQSVLTITSN VVYGKKTGNT PDGRRAGAPF GPGANPMHGR DQKGAVASLT SVAKLPFAYA 660
  661 KDGISYTFSI VPNALGKDDE VRKTNLAGLM DGYFHHEASI EGGQHLNVNV MNREMLLDAM 720
  721 EHPEKYPQLT IRVSGYAVRF NSLTKEQQQD VITRTFTQTM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1h16A
Description:	Pyruvate formate-lyase, PFL
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.95058695475279	bayes_pls_golite062009
oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	1.72563679072631	bayes_pls_golite062009
oxidoreductase activity, acting on CH or CH2 groups	1.43559439297918	bayes_pls_golite062009
oxidoreductase activity	1.42705638794743	bayes_pls_golite062009
ribonucleoside-diphosphate reductase activity	1.37298861502572	bayes_pls_golite062009
C-acyltransferase activity	0.0923196663496405	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: