YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|190407489
Organism:	Saccharomyces cerevisiae RM11-1a
Length:	397 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190407489.

Description	E-value	Query Range	Subject Range
gi\|151945790 - gi\|151945790\|gb\|EDN64031.1\| conserved protein [Saccharomyces cerevisiae YJM789] DCS2 - Non-essential, stress induced regulatory protein containing a HIT (histidine triad) motif; modulates... gi\|190407489 - gi\|190407489\|gb\|EDV10756.1\| hypothetical protein SCRG_01564 [Saccharomyces cerevisiae RM11-1a]	0.0	[1..397]	[1..397]
nhm1 - m7G(5')pppN diphosphatase DCPS_SCHPO - m7GpppX diphosphatase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nhm1 PE=1 SV=1	0.0	[53..366]	[11..297]
DCPS - decapping enzyme, scavenger	0.0	[57..366]	[47..329]
DCPS_MOUSE - m7GpppX diphosphatase OS=Mus musculus GN=Dcps PE=1 SV=1	0.0	[57..363]	[46..325]
dcs-1 - status:Confirmed UniProt:Q9U2Y7 protein_id:CAB60481.1	2.0E-93	[56..374]	[27..310]
gi\|19069424, gi\|... - gi\|19074782\|ref\|NP_586288.1\| hypothetical protein ECU10_1710 [Encephalitozoon cuniculi GB-M1], gi\|19... gi\|19074782 - ref\|NP_586288.1\| hypothetical protein [Encephalitozoon cuniculi]	6.0E-63	[76..352]	[24..254]

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Predicted Domain #1

Region A:
Residues: [1-397]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIKAERRET EARGFRLVFK YMLGRYLFIA KLKRFERVKV KKYMMGSQDL ASLIGRFKYV  60
   61 RVLDSNPHTK VISLLGSIDG KDAVLTAEKT HFIFDETVRR PSQSGRSTPI FFHREIDEYS 120
  121 FLNGITDLKE LTSNDIYYWG LSVLKQHILH NPTAKVNLIW PASQFHIKGY DQQDLHVVRE 180
  181 TPDMYRNIVV PFIQEMCTSE RMKWVNNILY EGAEDDRVVY KEYSSRNKED GFVILPDMKW 240
  241 DGINIDSLYL VAIVYRDDIK SLRDLNPNHR DWLIRLNKKI KTIIPQHYDY NVNPDELRVF 300
  301 IHYQPSYYHF HVHIVNIRHP GVGEERGSGM TILLEDVIEA LGFLGPEGYM KKTLTYVIGE 360
  361 NHDLWKKGFK EEVEKQLKHD GIATSPEKGS GFNTNLG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
m7G(5')pppN diphosphatase activity	11.4290795741181	bayes_pls_golite062009
RNA binding	2.65561768780165	bayes_pls_golite062009
nucleic acid binding	1.24536295645879	bayes_pls_golite062009
binding	1.12315862086587	bayes_pls_golite062009
hydrolase activity	0.927269748430359	bayes_pls_golite062009
catalytic activity	0.096119422680995	bayes_pls_golite062009
protein binding	0.0635855651106229	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: