YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|209921622, gi...
Organism:	Escherichia coli SE11
Length:	715 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|209921622, gi....

Description	E-value	Query Range	Subject Range
gi\|110644490, gi... - gi\|110644490\|ref\|YP_672220.1\| lysine decarboxylase, inducible [Escherichia coli 536], gi\|110346082\|g...	509.0	[0..1]	[715..1]
gi\|237703722, gi... - gi\|237703722\|ref\|ZP_04534203.1\| lysine decarboxylase 1 [Escherichia sp. 3_2_53FAA], gi\|226901634\|gb\|... gi\|26111380, gi\|... - gi\|26250948\|ref\|NP_756988.1\| lysine decarboxylase, inducible [Escherichia coli CFT073], gi\|26111380\|... gi\|91075255, gi\|... - gi\|91213681\|ref\|YP_543667.1\| CadA, subunit of lysine decarboxylase [Escherichia coli UTI89], gi\|9107...	509.0	[0..1]	[715..3]
gi\|115515540, gi... - gi\|117626416\|ref\|YP_859739.1\| lysine decarboxylase 1 [Escherichia coli APEC O1], gi\|115515540\|gb\|ABJ... gi\|227886828, gi... - gi\|227886828\|ref\|ZP_04004633.1\| lysine decarboxylase 1 [Escherichia coli 83972], gi\|227836170\|gb\|EEJ...	508.0	[0..1]	[715..14]
gi\|28807916, gi\|... - gi\|44886080\|dbj\|BAD12083.1\| lysine decarboxylase [Vibrio parahaemolyticus], gi\|28807916\|dbj\|BAC61153... gi\|28807916, gi\|... - gi\|28899664\|ref\|NP_799269.1\| lysine decarboxylase [Vibrio parahaemolyticus RIMD 2210633], gi\|2880791...	505.0	[0..1]	[710..1]
gi\|91187424, gi\|... - gi\|91229245\|ref\|ZP_01262906.1\| lysine decarboxylase [Vibrio alginolyticus 12G01], gi\|91187424\|gb\|EAS...	505.0	[0..1]	[710..1]
gi\|229353608, gi... - gi\|229509293\|ref\|ZP_04398776.1\| lysine decarboxylase [Vibrio cholerae B33], gi\|229353608\|gb\|EEO18545... gi\|254847122, gi... - gi\|75831188\|ref\|ZP_00760454.1\| COG1982: Arginine/lysine/ornithine decarboxylases [Vibrio cholerae MO... gi\|229516239, gi... - gi\|229516239\|ref\|ZP_04405687.1\| lysine decarboxylase [Vibrio cholerae RC9], gi\|229346665\|gb\|EEO11635... gi\|229369088, gi... - gi\|229606433\|ref\|YP_002877081.1\| lysine decarboxylase [Vibrio cholerae MJ-1236], gi\|229369088\|gb\|ACQ... gi\|9654692, gi\|1... - gi\|9654692\|gb\|AAF93456.1\| lysine decarboxylase, inducible [Vibrio cholerae O1 biovar El Tor str. N16... gi\|11280589 - pir\|\|E82342 lysine decarboxylase, inducible VC0281 [imported] - Vibrio cholerae (strain N16961 serog...	504.0	[0..1]	[711..23]
gi\|229335232, gi... - gi\|229527224\|ref\|ZP_04416617.1\| lysine decarboxylase [Vibrio cholerae 12129(1)], gi\|229335232\|gb\|EEO... gi\|229521003, gi... - gi\|229521003\|ref\|ZP_04410424.1\| lysine decarboxylase [Vibrio cholerae TM 11079-80], gi\|229341888\|gb\|... gi\|254225651, gi... - gi\|254225651\|ref\|ZP_04919258.1\| lysine decarboxylase, inducible [Vibrio cholerae V51], gi\|194537158\|... gi\|75828257, gi\|... - gi\|75828257\|ref\|ZP_00757692.1\| COG1982: Arginine/lysine/ornithine decarboxylases [Vibrio cholerae O3... gi\|153801509, gi... - gi\|153801509\|ref\|ZP_01956095.1\| lysine decarboxylase, inducible [Vibrio cholerae MZO-3], gi\|12412291... gi\|75823526, gi\|... - gi\|75823526\|ref\|ZP_00753021.1\| COG1982: Arginine/lysine/ornithine decarboxylases [Vibrio cholerae RC... gi\|121630544, gi... - gi\|121727033\|ref\|ZP_01680224.1\| lysine decarboxylase, inducible [Vibrio cholerae V52], gi\|121630544\|... tr\|A2PRU6\|A2PRU6... - Lysine decarboxylase, inducible OS=Vibrio cholerae MZO-3 GN=cadA PE=4 SV=1, Lysine decarboxylase OS=... gi\|148874126, gi... - gi\|153830392\|ref\|ZP_01983059.1\| lysine decarboxylase, inducible [Vibrio cholerae 623-39], gi\|1488741... gi\|229512722, gi... - gi\|229512722\|ref\|ZP_04402190.1\| lysine decarboxylase [Vibrio cholerae TMA 21], gi\|229350232\|gb\|EEO15...	503.0	[0..1]	[711..23]
gi\|12698732 - gi\|12698732\|gb\|AAK01664.1\|AF324470_2 lysine decarboxylase [Vibrio vulnificus] gi\|37199313, gi\|... - gi\|37680565\|ref\|NP_935174.1\| lysine decarboxylase [Vibrio vulnificus YJ016], gi\|37199313\|dbj\|BAC9514... gi\|161501814 - gi\|161501814\|ref\|NP_760922.2\| lysine decarboxylase [Vibrio vulnificus CMCP6]	501.0	[0..1]	[711..1]
gi\|75514891 - gi\|75514891\|ref\|ZP_00737120.1\| COG1982: Arginine/lysine/ornithine decarboxylases [Escherichia coli 5...	500.0	[0..16]	[715..7]
gi\|59712664, gi\|... - gi\|59712664\|ref\|YP_205440.1\| lysine decarboxylase 1 [Vibrio fischeri ES114], gi\|59480765\|gb\|AAW86552...	500.0	[0..1]	[711..1]

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Predicted Domain #1

Region A:
Residues: [1-715]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVIAILNHM GVYFKEEPIR ELHRALERLN FQIVYPNDRD DLLKLIENNA RLCGVIFDWD  60
   61 KYNLELCEEI SKMNENLPLY AFANTYSTLD VSLNDLRLQI SFFEYALGAA EDIANKIKQT 120
  121 TDEYINTILP PLTKALFKYV REGKYTFCTP GHMGGTAFQK SPVGSLFYDF FGPNTMKSDI 180
  181 SISVSELGSL LDHSGPHKEA EQYIARVFNA DRSYMVTNGT STANKIVGMY SAPAGSTILI 240
  241 DRNCHKSLTH LMMMSDVTPI YFRPTRNAYG ILGGIPQSEF QHATIAKRVK ETPNATWPVH 300
  301 AVITNSTYDG LLYNTDFIKK TLDVKSIHFD SAWVPYTNFS PIYEGKCGMS GGRVEGKVIY 360
  361 ETQSTHKLLA AFSQASMIHV KGDVNEETFN EAYMMHTTTS PHYGIVASTE TAAAMMKGNA 420
  421 GKRLINGSIE RAIKFRKEIK RLRTESDGWF FDVWQPDHID TTECWPLRSD STWHGFKNID 480
  481 NEHMYLDPIK VTLLTPGMEK DGTMSDFGIP ASIVAKYLDE HGIVVEKTGP YNLLFLFSIG 540
  541 IDKTKALSLL RALTDFKRAF DLNLRVKNML PSLYREDPEF YENMRIQELA QNIHKLIVHH 600
  601 NLPDLMYRAF EVLPTMVMTP YAAFQKELHG MTEEVYLDEM VGRINANMIL PYPPGVPLVM 660
  661 PGEMITEESR PVLEFLQMLC EIGAHYPGFE TDIHGAYRQA DGRYTVKVLK EESKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	96.69897
Match:	1ordA
Description:	Ornithine decarboxylase N-terminal "wing" domain; Ornithine decarboxylase major domain; Ornithine decarboxylase C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.29878871754893	bayes_pls_golite062009
signal transducer activity	2.07885074402355	bayes_pls_golite062009
molecular transducer activity	2.07885074402355	bayes_pls_golite062009
two-component response regulator activity	1.53373140048441	bayes_pls_golite062009
transferase activity	1.44093490824786	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	0.73470270006811	bayes_pls_golite062009
binding	0.252160165096264	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009
carbon-carbon lyase activity	0.11598778799668	bayes_pls_golite062009
4-aminobutyrate transaminase activity	0.0779403509221881	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: