YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|194450350, gi...
Organism:	Salmonella enterica subsp. enterica serovar Heidelberg str. SL476
Length:	469 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|194450350, gi....

Description	E-value	Query Range	Subject Range
gi\|21730907, gi\|... - gi\|21730914\|pdb\|2GLS\|L Chain L, Refined Atomic Model Of Glutamine Synthetase At 3.5 Angstroms Resolu... gi\|21730911\|pdb\|... - Chain H, Refined Atomic Model Of Glutamine Synthetase At 3.5 Angstroms Resolution, Chain G, Refined ...	0.0	[1..469]	[1..469]
gi\|254595263, gi... - gi\|254795863\|ref\|YP_003080700.1\| glutamine synthetase [Escherichia coli O157:H7 str. TW14359], gi\|25... gi\|253975722, gi... - gi\|254163821\|ref\|YP_003046929.1\| glutamine synthetase [Escherichia coli B str. REL606], gi\|253975722... gi\|226838519, gi... - gi\|254039083\|ref\|ZP_04873133.1\| glutamine synthetase [Escherichia sp. 1_1_43], gi\|226838519\|gb\|EEH70... gi\|254290571, gi... - gi\|254290571\|ref\|YP_003056319.1\| glutamine synthetase [Escherichia coli BL21(DE3)], gi\|253979878\|gb\|... gi\|251787134, gi... - gi\|251787134\|ref\|YP_003001438.1\| hypothetical protein B21_03704 [Escherichia coli BL21], gi\|24237940... gi\|238861338, gi... - gi\|238902937\|ref\|YP_002928733.1\| glutamine synthetase [Escherichia coli BW2952], gi\|238861338\|gb\|ACR... gi\|226902839, gi... - gi\|237702902\|ref\|ZP_04533383.1\| glutamine synthetase [Escherichia sp. 3_2_53FAA], gi\|226902839\|gb\|EE... gi\|227885394, gi... - gi\|227885394\|ref\|ZP_04003199.1\| glutamate--ammonia ligase [Escherichia coli 83972], gi\|227837652\|gb\|... gi\|218556429, gi... - gi\|218556429\|ref\|YP_002389343.1\| glutamine synthetase [Escherichia coli IAI1], gi\|218363198\|emb\|CAR0... gi\|218367714, gi... - gi\|218560945\|ref\|YP_002393858.1\| glutamine synthetase [Escherichia coli S88], gi\|218367714\|emb\|CAR05... gi\|218697583, gi... - gi\|218697583\|ref\|YP_002405250.1\| glutamine synthetase [Escherichia coli 55989], gi\|218354315\|emb\|CAV... gi\|218701431, gi... - gi\|218701431\|ref\|YP_002409060.1\| glutamine synthetase [Escherichia coli IAI39], gi\|218371417\|emb\|CAR... gi\|218707495, gi... - gi\|218707495\|ref\|YP_002415014.1\| glutamine synthetase [Escherichia coli UMN026], gi\|218434592\|emb\|CA... gi\|188493780, gi... - gi\|75513981\|ref\|ZP_00736334.1\| COG0174: Glutamine synthetase [Escherichia coli 53638], gi\|188493780\|... gi\|195937508 - gi\|195937508\|ref\|ZP_03082890.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC4024] gi\|73857852, gi\|... - gi\|74314375\|ref\|YP_312794.1\| glutamine synthetase [Shigella sonnei Ss046], gi\|73857852\|gb\|AAZ90559.1... gi\|208806054, gi... - gi\|208806054\|ref\|ZP_03248391.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC4206], gi\|2087... gi\|75238312, gi\|... - gi\|75238312\|ref\|ZP_00722311.1\| COG0174: Glutamine synthetase [Escherichia coli E110019], gi\|19306805... gi\|208812732, gi... - gi\|208812732\|ref\|ZP_03254061.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC4045], gi\|2087... gi\|75258148, gi\|... - gi\|75258148\|ref\|ZP_00729609.1\| COG0174: Glutamine synthetase [Escherichia coli E22], gi\|193063961\|re... gi\|208818507, gi... - gi\|208818507\|ref\|ZP_03258827.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC4042], gi\|2087... gi\|81247625, gi\|... - gi\|82546214\|ref\|YP_410161.1\| glutamine synthetase [Shigella boydii Sb227], gi\|81247625\|gb\|ABB68333.1... gi\|209400069, gi... - gi\|209400069\|ref\|YP_002273386.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC4115], gi\|209... gi\|89110158, gi\|... - gi\|89110158\|ref\|AP_003938.1\| glutamine synthetase [Escherichia coli str. K-12 substr. W3110], gi\|856... gi\|209921344, gi... - gi\|209921344\|ref\|YP_002295428.1\| glutamine synthetase [Escherichia coli SE11], gi\|209914603\|dbj\|BAG7... GLNA_ECOL6 - Glutamine synthetase OS=Escherichia coli O6 GN=glnA PE=3 SV=2 gi\|215267275, gi... - gi\|215489203\|ref\|YP_002331634.1\| glutamine synthetase [Escherichia coli O127:H6 str. E2348/69], gi\|2... gi\|81243104, gi\|... - gi\|82778956\|ref\|YP_405305.1\| glutamine synthetase [Shigella dysenteriae Sd197], gi\|81243104\|gb\|ABB63... gi\|217320961, gi... - gi\|217324740\|ref\|ZP_03440824.1\| glutamine synthetase [Escherichia coli O157:H7 str. TW14588], gi\|217... gi\|187429216, gi... - gi\|75176745\|ref\|ZP_00696873.1\| COG0174: Glutamine synthetase [Shigella boydii BS512], gi\|187732224\|r... gi\|75188604, gi\|... - gi\|75188604\|ref\|ZP_00701871.1\| COG0174: Glutamine synthetase [Escherichia coli E24377A], gi\|15715589... gi\|194438335, gi... - gi\|83586281\|ref\|ZP_00924917.1\| COG0174: Glutamine synthetase [Escherichia coli 101-1], gi\|194438335\|... gi\|191166401, gi... - gi\|75230390\|ref\|ZP_00716876.1\| COG0174: Glutamine synthetase [Escherichia coli B7A], gi\|191166401\|re... gi\|75237835, gi\|... - gi\|75237835\|ref\|ZP_00721850.1\| COG0174: Glutamine synthetase [Escherichia coli F11], gi\|191173898\|re... gi\|157069022, gi... - gi\|75197745\|ref\|ZP_00707815.1\| COG0174: Glutamine synthetase [Escherichia coli HS], gi\|157163342\|ref... gi\|75210113, gi\|... - gi\|75210113\|ref\|ZP_00710292.1\| COG0174: Glutamine synthetase [Escherichia coli B171], gi\|194428687\|r... gi\|110616994, gi... - gi\|110807446\|ref\|YP_690966.1\| glutamine synthetase [Shigella flexneri 5 str. 8401], gi\|110616994\|gb\|... gi\|91074990, gi\|... - gi\|91213416\|ref\|YP_543402.1\| glutamine synthetase [Escherichia coli UTI89], gi\|91074990\|gb\|ABE09871.... gi\|15834046, gi\|... - gi\|15834046\|ref\|NP_312819.1\| glutamine synthetase [Escherichia coli O157:H7 str. Sakai], gi\|13364268... gi\|110644210, gi... - gi\|110644210\|ref\|YP_671940.1\| glutamine synthetase [Escherichia coli 536], gi\|110345802\|gb\|ABG72039.... GLNA_SHIFL - Glutamine synthetase OS=Shigella flexneri GN=glnA PE=3 SV=2 GLNA_ECOLI - Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase) - Escherichia coli gi\|24054435, gi\|... - gi\|24115158\|ref\|NP_709668.1\| glutamine synthetase [Shigella flexneri 2a str. 301], gi\|24054435\|gb\|AA... GLNA_ECOL6 - Glutamine synthetase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=glnA PE=3 SV=... gi\|168768158, gi... - gi\|189362646\|gb\|EDU81065.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC4486], gi\|16876815... gi\|187769193, gi... - gi\|187769193\|gb\|EDU33037.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC4196], gi\|16877531... gi\|189001594, gi... - gi\|189001594\|gb\|EDU70580.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC4076], gi\|16878077... gi\|189373345, gi... - gi\|189373345\|gb\|EDU91761.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC869], gi\|168786713... gi\|117626143, gi... - gi\|117626143\|ref\|YP_859466.1\| glutamine synthetase [Escherichia coli APEC O1], gi\|115515267\|gb\|ABJ03... gi\|168799566, gi... - gi\|189378048\|gb\|EDU96464.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC508], gi\|168799566... gi\|124527533, gi... - gi\|124527533\|ref\|ZP_01698998.1\| glutamine synthetase, type I [Escherichia coli B], gi\|124501235\|gb\|E... gi\|169757044, gi... - gi\|170022116\|ref\|YP_001727070.1\| glutamine synthetase [Escherichia coli ATCC 8739], gi\|169757044\|gb\|... gi\|170083342, gi... - gi\|170083342\|ref\|YP_001732662.1\| glutamine synthetase [Escherichia coli str. K-12 substr. DH10B], gi... gi\|170518566, gi... - gi\|170680848\|ref\|YP_001746200.1\| glutamine synthetase [Escherichia coli SMS-3-5], gi\|170518566\|gb\|AC... EG10383 - glutamine synthetase / Glutamine synthase gi\|188016770, gi... - gi\|188016770\|gb\|EDU54892.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC4113], gi\|16874884... gi\|189357123, gi... - gi\|189357123\|gb\|EDU75542.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC4401], gi\|16875554... gi\|168761761, gi... - gi\|189367951\|gb\|EDU86367.1\| glutamine synthetase [Escherichia coli O157:H7 str. EC4501], gi\|16876176... gi\|30064841, gi\|... - gi\|30064841\|ref\|NP_839012.1\| glutamine synthetase [Shigella flexneri 2a str. 2457T], gi\|30043101\|gb\|... GLNA_ECO57 - Glutamine synthetase OS=Escherichia coli O157:H7 GN=glnA PE=3 SV=2 EG10383 - glutamine synthetase / Glutamine synthase	0.0	[1..469]	[1..469]
gi\|194435178, gi... - gi\|83568944\|ref\|ZP_00920410.1\| COG0174: Glutamine synthetase [Shigella dysenteriae 1012], gi\|1944351...	0.0	[1..469]	[1..469]
gi\|12518749, gi\|... - gi\|15804455\|ref\|NP_290495.1\| glutamine synthetase [Escherichia coli O157:H7 EDL933], gi\|12518749\|gb\|... gi\|25293493 - gi\|25293493\|pir\|\|G86074 glutamine synthetase [imported] - Escherichia coli (strain O157:H7, substrai...	0.0	[1..469]	[1..469]
gi\|3808290 - gi\|3808290\|gb\|AAC69320.1\| glutamine synthetase [Enterobacter gergoviae]	0.0	[1..469]	[1..469]
gi\|78691127, gi\|... - gi\|78691127\|ref\|ZP_00855756.1\| Glutamine synthetase type I [Shewanella sp. MR-7], gi\|78509465\|gb\|EAP... gi\|82495545, gi\|... - gi\|82495545\|ref\|ZP_00881120.1\| Glutamine synthetase type I [Shewanella sp. MR-4], gi\|82406429\|gb\|EAP...	0.0	[1..469]	[1..469]
gi\|23630225 - gi\|23630225\|gb\|AAN37400.1\| glutamine synthetase [Pantoea agglomerans]	0.0	[1..469]	[1..469]
gi\|146157 - gi\|146157\|gb\|AAA23879.1\| glutamine synthetase [Escherichia coli]	0.0	[1..469]	[1..469]

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Predicted Domain #1

Region A:
Residues: [1-469]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAEHVLTML NEHEVKFVDL RFTDTKGKEQ HVTIPAHQVN AEFFEEGKMF DGSSIGGWKG  60
   61 INESDMVLMP DASTAVIDPF FADSTLIIRC DILEPGTLQG YDRDPRSIAK RAEDYLRATG 120
  121 IADTVLFGPE PEFFLFDDIR FGASISGSHV AIDDIEGAWN SSTKYEGGNK GHRPGVKGGY 180
  181 FPVPPVDSAQ DIRSEMCLVM EQMGLVVEAH HHEVATAGQN EVATRFNTMT KKADEIQIYK 240
  241 YVVHNVAHRF GKTATFMPKP MFGDNGSGMH CHMSLAKNGT NLFSGDKYAG LSEQALYYIG 300
  301 GVIKHAKAIN ALANPTTNSY KRLVPGYEAP VMLAYSARNR SASIRIPVVA SPKARRIEVR 360
  361 FPDPAANPYL CFAALLMAGL DGIKNKIHPG EAMDKNLYDL PPEEAKEIPQ VAGSLEEALN 420
  421 ALDLDREFLK AGGVFTDEAI DAYIALRREE DDRVRMTPHP VEFELYYSV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	174.0
Match:	2glsA
Description:	Glutamine synthetase, N-terminal domain; Glutamine synthetase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ammonia ligase activity	6.27241182807427	bayes_pls_golite062009
acid-ammonia (or amide) ligase activity	5.91942691148686	bayes_pls_golite062009
ligase activity	1.87132312522382	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	1.62421495628324	bayes_pls_golite062009
catalytic activity	1.08973967683802	bayes_pls_golite062009
binding	0.98415932762563	bayes_pls_golite062009
nucleic acid binding	0.873840044936337	bayes_pls_golite062009
protein binding	0.232967538442099	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: