YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|214041268, gi...
Organism:	Marinitoga piezophila KA3
Length:	166 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|214041268, gi....

Description	E-value	Query Range	Subject Range
gi\|55670468, gi\|... - gi\|55670469\|pdb\|1VMD\|B Chain B, Crystal Structure Of Methylglyoxal Synthase (Tm1185) From Thermotoga...	274.0	[0..1]	[166..13]
gi\|90439871, gi\|... - gi\|90579038\|ref\|ZP_01234848.1\| methylglyoxal synthase [Vibrio angustum S14], gi\|90439871\|gb\|EAS65052...	249.0	[0..12]	[156..8]
MGSA_HAES1 - Methylglyoxal synthase OS=Haemophilus somnus (strain 129Pt) GN=mgsA PE=3 SV=1	248.0	[0..12]	[156..8]
MGSA_HISS2 - Methylglyoxal synthase OS=Histophilus somni (strain 2336) GN=mgsA PE=3 SV=1	247.0	[0..12]	[156..8]
MGSA_VIBPA - Methylglyoxal synthase OS=Vibrio parahaemolyticus GN=mgsA PE=3 SV=1 MGSA_VIBPA - Methylglyoxal synthase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=mgsA PE=3 ... gi\|153838728, gi... - gi\|153838728\|ref\|ZP_01991395.1\| methylglyoxal synthase [Vibrio parahaemolyticus AQ3810], gi\|14974785...	247.0	[0..12]	[155..8]
gi\|168237130, gi... - gi\|197289819\|gb\|EDY29180.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar Schw... gi\|205332439, gi... - gi\|205332439\|gb\|EDZ19203.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar Kent... gi\|205327305, gi... - gi\|205327305\|gb\|EDZ14069.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar 4,[5... gi\|205322790, gi... - gi\|205322790\|gb\|EDZ10629.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar Sain... MGSA_SALTI - Methylglyoxal synthase OS=Salmonella typhi GN=mgsA PE=3 SV=1 gi\|168821817, gi... - gi\|205341665\|gb\|EDZ28429.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar Welt... MGSA_SALTY - Methylglyoxal synthase OS=Salmonella typhimurium GN=mgsA PE=3 SV=1 gi\|168467517, gi... - gi\|195630089\|gb\|EDX48741.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar Newp... gi\|168264163, gi... - gi\|205347376\|gb\|EDZ34007.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar Hada... gi\|168243866, gi... - gi\|205337177\|gb\|EDZ23941.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar Heid... MGSA_SALTI - Methylglyoxal synthase OS=Salmonella typhi GN=mgsA PE=3 SV=1 gi\|16759957 - gi\|16759957\|ref\|NP_455574.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar Typ... MGSA_SALTY - Methylglyoxal synthase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=mgsA PE=3 ... gi\|29142271, gi\|... - gi\|29142271\|ref\|NP_805613.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar Typ... gi\|213028755 - gi\|213028755\|ref\|ZP_03343202.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... MGSA_SALEP - Methylglyoxal synthase OS=Salmonella enteritidis PT4 (strain P125109) GN=mgsA PE=3 SV=1 gi\|204930730, gi... - gi\|204930730\|ref\|ZP_03221603.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... gi\|200390828, gi... - gi\|200390828\|ref\|ZP_03217439.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... gi\|213580190 - gi\|213580190\|ref\|ZP_03362016.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... gi\|213425897 - gi\|213425897\|ref\|ZP_03358647.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... gi\|213417512 - gi\|213417512\|ref\|ZP_03350654.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... MGSA_SALCH - Methylglyoxal synthase OS=Salmonella choleraesuis GN=mgsA PE=3 SV=1 gi\|213160861 - gi\|213160861\|ref\|ZP_03346571.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... MGSA_SALSV - Methylglyoxal synthase OS=Salmonella schwarzengrund (strain CVM19633) GN=mgsA PE=3 SV=1 gi\|194469885, gi... - gi\|194469885\|ref\|ZP_03075869.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... MGSA_SALHS - Methylglyoxal synthase OS=Salmonella heidelberg (strain SL476) GN=mgsA PE=3 SV=1 MGSA_SALNS - Methylglyoxal synthase OS=Salmonella newport (strain SL254) GN=mgsA PE=3 SV=1 MGSA_SALPB - Methylglyoxal synthase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=mgsA PE=3 SV=1 MGSA_SALDC - Methylglyoxal synthase OS=Salmonella dublin (strain CT_02021853) GN=mgsA PE=3 SV=1 MGSA_SALPA - Methylglyoxal synthase OS=Salmonella paratyphi A GN=mgsA PE=3 SV=1 MGSA_SALPK - Methylglyoxal synthase OS=Salmonella paratyphi A (strain AKU_12601) GN=mgsA PE=3 SV=1 MGSA_SALCH - Methylglyoxal synthase OS=Salmonella choleraesuis GN=mgsA PE=3 SV=1 gi\|197265815, gi... - gi\|197265815\|ref\|ZP_03165889.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... MGSA_SALAR - Methylglyoxal synthase OS=Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) GN=mgsA PE... MGSA_SALA4 - Methylglyoxal synthase OS=Salmonella agona (strain SL483) GN=mgsA PE=3 SV=1 gi\|238911101 - gi\|238911101\|ref\|ZP_04654938.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... MGSA_SALTY - Methylglyoxal synthase OS=Salmonella typhimurium GN=mgsA PE=3 SV=1 MGSA_SALCH - Methylglyoxal synthase OS=Salmonella choleraesuis (strain SC-B67) GN=mgsA PE=3 SV=1 MGSA_SALPA - Methylglyoxal synthase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=mgsA PE=3 SV=1 MGSA_SALPC - Methylglyoxal synthase OS=Salmonella paratyphi C (strain RKS4594) GN=mgsA PE=3 SV=1 gi\|214001663 - gi\|214001663\|ref\|ZP_03412398.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... gi\|213647172 - gi\|213647172\|ref\|ZP_03377225.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... gi\|213622021 - gi\|213622021\|ref\|ZP_03374804.1\| methylglyoxal synthase [Salmonella enterica subsp. enterica serovar ... lcl\|NC_016856.1_... - [gene=mgsA] [protein=methylglyoxal synthase] [protein_id=YP_005236810.1] [location=complement(112686... MGSA_SALPB - Methylglyoxal synthase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=mgsA PE=3 SV=1	247.0	[0..12]	[156..8]
gi\|89049676, gi\|... - gi\|89074572\|ref\|ZP_01161044.1\| methylglyoxal synthase [Photobacterium sp. SKA34], gi\|89049676\|gb\|EAR...	247.0	[0..12]	[156..8]
gi\|194539096, gi... - gi\|75855948\|ref\|ZP_00763586.1\| COG1803: Methylglyoxal synthase [Vibrio sp. Ex25], gi\|254229815\|ref\|Z... gi\|91188321, gi\|... - gi\|91227912\|ref\|ZP_01262051.1\| methylglyoxal synthase [Vibrio alginolyticus 12G01], gi\|91188321\|gb\|E...	246.0	[0..12]	[155..8]
gi\|77974894 - gi\|77974894\|ref\|ZP_00830432.1\| COG1803: Methylglyoxal synthase [Yersinia frederiksenii ATCC 33641]	246.0	[0..12]	[156..34]

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Predicted Domain #1

Region A:
Residues: [1-166]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDRPRRYKI FMDKKKRIAL IAHDRRKRDL LEWVSFNLGT LSKHELYATG TTGALLQEKL  60
   61 GLKVHRLKSG PLGGDQQIGA MIAEGKIDVL IFFWDPLEPQ AHDVDVKALI RIATVYNIPV 120
  121 AITRSTADFL ISSPLMNDVY EKIQIDYEEE LERRIRKVVE GEEEET

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	74.09691
Match:	1vmdA
Description:	Crystal structure of Methylglyoxal synthase (TM1185) from Thermotoga maritima at 2.06 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methylglyoxal synthase activity	7.67158041469211	bayes_pls_golite062009
catalytic activity	2.05174935916901	bayes_pls_golite062009
carbon-oxygen lyase activity	0.8193600732138	bayes_pls_golite062009
carbon-oxygen lyase activity, acting on phosphates	0.74427062677768	bayes_pls_golite062009
lyase activity	0.129701662862796	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: