YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|170288290, gi...
Organism:	Thermotoga sp. RQ2
Length:	171 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|170288290, gi....

Description	E-value	Query Range	Subject Range
gi\|17933427 - gi\|17933427\|gb\|AAL48287.1\|AF452495_1 aminoimidazole ribonucleotide carboxylase [Vigna unguiculata]	257.0	[0..2]	[169..466]
gi\|18976799, gi\|... - gi\|18976799\|ref\|NP_578156.1\| phosphoribosylaminoimidazole carboxylase catalytic subunit [Pyrococcus ...	255.0	[0..1]	[170..1]
gi\|34811258 - gi\|34811258\|pdb\|1O4V\|A Chain A, Crystal Structure Of Phosphoribosylaminoimidazole Mutase Pure (Tm044...	254.0	[0..2]	[171..14]
PUR6_CANGA - Phosphoribosylaminoimidazole carboxylase OS=Candida glabrata GN=ADE2 PE=3 SV=2 PUR6_CANGA - Phosphoribosylaminoimidazole carboxylase OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 ...	253.0	[0..2]	[170..402]
PURE_PYRAB - N5-carboxyaminoimidazole ribonucleotide mutase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=purE PE=... PUR6_PYRAB - Phosphoribosylaminoimidazole carboxylase catalytic subunit OS=Pyrococcus abyssi GN=purE PE=3 SV=1	250.0	[0..1]	[168..6]
gi\|110737176, gi... - gi\|42569706\|ref\|NP_181305.2\| phosphoribosylaminoimidazole carboxylase, putative / AIR carboxylase, p...	250.0	[0..2]	[169..475]
gi\|3342244 - gi\|3342244\|gb\|AAC27548.1\| aminoimidazole ribonucleotide carboxylase [Candida glabrata]	250.0	[0..2]	[170..402]
gi\|186685339, gi... - gi\|23124081\|ref\|ZP_00106095.1\| COG0041: Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nostoc p...	247.0	[0..2]	[170..3]
gi\|115435108, gi... - gi\|66274576\|dbj\|BAD98622.1\| putative phosphoribosylaminoimidazole carboxylase, chloroplast precursor...	247.0	[0..2]	[168..459]

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Predicted Domain #1

Region A:
Residues: [1-171]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRVGIIMGS DSDLPVMKQA AEILEEFGID YEITIVSAHR TPDRMFEYAK NAEERGIEVI  60
   61 IAGAGGAAHL PGMVASITHL PVIGVPVKTS TLNGLDSLFS IVQMPGGVPV ATVAINNAKN 120
  121 AGILAASILG IKYPEIARKV KEYKERMKRE VLEKAQRLEQ IGYKEYLNQK E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.154902
Match:	1o4vA
Description:	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoribosylaminoimidazole carboxylase activity	12.126616405613	bayes_pls_golite062009
carboxy-lyase activity	8.23768576957333	bayes_pls_golite062009
catalytic activity	1.94758748334979	bayes_pls_golite062009
carbon-carbon lyase activity	0.735133792277863	bayes_pls_golite062009
lyase activity	0.685887227538264	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: