YRC Public Data Repository - Protein Structure Prediction

Protein:	MGSA_SALPC
Organism:	Salmonella enterica subsp. enterica serovar Paratyphi C strain RKS4594
Length:	152 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MGSA_SALPC.

Description	E-value	Query Range	Subject Range
MGSA_VIBPA - Methylglyoxal synthase OS=Vibrio parahaemolyticus GN=mgsA PE=3 SV=1 MGSA_VIBPA - Methylglyoxal synthase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=mgsA PE=3 ... gi\|153838728, gi... - gi\|153838728\|ref\|ZP_01991395.1\| methylglyoxal synthase [Vibrio parahaemolyticus AQ3810], gi\|14974785...	2.0E-71	[1..151]	[1..151]
MGSA_ECO81 - Methylglyoxal synthase OS=Escherichia coli O81 (strain ED1a) GN=mgsA PE=3 SV=1 sp\|B7UN42\|MGSA_ECO27 - Methylglyoxal synthase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=mgsA PE=3 SV=1 gi\|190907301, gi... - gi\|191172417\|ref\|ZP_03033958.1\| methylglyoxal synthase [Escherichia coli F11], gi\|190907301\|gb\|EDV66... MGSA_ECOL6 - Methylglyoxal synthase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=mgsA PE=3 S... MGSA_ECO45 - Methylglyoxal synthase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=mgsA PE=3 SV=1 MGSA_ECOL6 - Methylglyoxal synthase OS=Escherichia coli O6 GN=mgsA PE=3 SV=2 MGSA_ECO27 - Methylglyoxal synthase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=mgsA PE=3 SV=1	4.0E-71	[1..152]	[1..152]
gi\|227884077, gi... - gi\|227884077\|ref\|ZP_04001882.1\| methylglyoxal synthase [Escherichia coli 83972], gi\|227838829\|gb\|EEJ... gi\|75240582 - gi\|75240582\|ref\|ZP_00724499.1\| COG1803: Methylglyoxal synthase [Escherichia coli F11] gi\|237707052, gi... - gi\|237707052\|ref\|ZP_04537533.1\| methylglyoxal synthase [Escherichia sp. 3_2_53FAA], gi\|226898262\|gb\|... gi\|91071633, gi\|... - gi\|91210059\|ref\|YP_540045.1\| methylglyoxal synthase [Escherichia coli UTI89], gi\|91071633\|gb\|ABE0651... gi\|110641153, gi... - gi\|110641153\|ref\|YP_668883.1\| methylglyoxal synthase [Escherichia coli 536], gi\|110342745\|gb\|ABG6898... gi\|26107385, gi\|... - gi\|26246985\|ref\|NP_753025.1\| methylglyoxal synthase [Escherichia coli CFT073], gi\|26107385\|gb\|AAN795... gi\|117623173, gi... - gi\|117623173\|ref\|YP_852086.1\| methylglyoxal synthase [Escherichia coli APEC O1], gi\|115512297\|gb\|ABJ...	4.0E-71	[1..152]	[4..155]
MGSA_ECOLI - Methylglyoxal synthase (EC 4.2.3.3) (MGS) - Escherichia coli MGSA_ECOLC - Methylglyoxal synthase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=mgsA PE=3 SV=1 gi\|189354359, gi... - gi\|189354359\|gb\|EDU72778.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. EC4401], gi\|168758... gi\|168751277, gi... - gi\|188014679\|gb\|EDU52801.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. EC4113], gi\|168751... gi\|162139803 - gi\|162139803\|ref\|NP_309074.2\| methylglyoxal synthase [Escherichia coli O157:H7 str. Sakai] gi\|161986558 - gi\|161986558\|ref\|YP_309939.2\| methylglyoxal synthase [Shigella sonnei Ss046] gi\|168787396, gi... - gi\|189372645\|gb\|EDU91061.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. EC869], gi\|1687873... gi\|168780910, gi... - gi\|189001251\|gb\|EDU70237.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. EC4076], gi\|168780... gi\|168777448, gi... - gi\|187767328\|gb\|EDU31172.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. EC4196], gi\|168777... gi\|189364953, gi... - gi\|189364953\|gb\|EDU83369.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. EC4501], gi\|168765... gi\|161367625 - gi\|161367625\|ref\|NP_286838.2\| methylglyoxal synthase [Escherichia coli O157:H7 EDL933] gi\|161984906 - gi\|161984906\|ref\|YP_408660.2\| methylglyoxal synthase [Shigella boydii Sb227] gi\|161950141 - gi\|161950141\|ref\|YP_402603.2\| methylglyoxal synthase [Shigella dysenteriae Sd197] MGSA_ECO57 - Methylglyoxal synthase OS=Escherichia coli O157:H7 GN=mgsA PE=3 SV=1 gi\|161486515 - gi\|161486515\|ref\|NP_836673.2\| methylglyoxal synthase [Shigella flexneri 2a str. 2457T] gi\|161485928 - gi\|161485928\|ref\|NP_706886.2\| methylglyoxal synthase [Shigella flexneri 2a str. 301] MGSA_ECO5E - Methylglyoxal synthase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=mgsA PE=3 SV=1 EG12307 - methylglyoxal synthase / Methylglyoxal synthase gi\|208816131, gi... - gi\|208816131\|ref\|ZP_03257310.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. EC4045], gi\|20... gi\|89107813, gi\|... - gi\|89107813\|ref\|AP_001593.1\| methylglyoxal synthase [Escherichia coli str. K-12 substr. W3110], gi\|8... gi\|208729001, gi... - gi\|208809200\|ref\|ZP_03251537.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. EC4206], gi\|20... gi\|195935150 - gi\|195935150\|ref\|ZP_03080532.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. EC4024] MGSA_ECO7I - Methylglyoxal synthase OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=mgsA PE=3 SV=1 MGSA_ECO8A - Methylglyoxal synthase OS=Escherichia coli O8 (strain IAI1) GN=mgsA PE=3 SV=1 gi\|217321005, gi... - gi\|217324784\|ref\|ZP_03440868.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. TW14588], gi\|2... MGSA_ECOSE - Methylglyoxal synthase OS=Escherichia coli (strain SE11) GN=mgsA PE=3 SV=1 MGSA_SHIB3 - Methylglyoxal synthase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=mgsA PE=3 SV=1 gi\|251784505, gi... - gi\|251784505\|ref\|YP_002998809.1\| hypothetical protein B21_00974 [Escherichia coli BL21], gi\|24237677... MGSA_ECOHS - Methylglyoxal synthase OS=Escherichia coli O9:H4 (strain HS) GN=mgsA PE=3 SV=1 MGSA_ECOSM - Methylglyoxal synthase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=mgsA PE=3 SV=1 MGSA_ECOBW - Methylglyoxal synthase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=mgsA PE=3 SV=1 MGSA_ECO24 - Methylglyoxal synthase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=mgsA PE=3 SV=1 MGSA_ECODH - Methylglyoxal synthase OS=Escherichia coli (strain K12 / DH10B) GN=mgsA PE=3 SV=1 gi\|253972978, gi... - gi\|254161077\|ref\|YP_003044185.1\| methylglyoxal synthase [Escherichia coli B str. REL606], gi\|2539729... gi\|189376500, gi... - gi\|189376500\|gb\|EDU94916.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. EC508], gi\|1688013... gi\|254287885, gi... - gi\|254287885\|ref\|YP_003053633.1\| methylglyoxal synthase [Escherichia coli BL21(DE3)], gi\|253977192\|g... gi\|194440052, gi... - gi\|194440052\|ref\|ZP_03072108.1\| methylglyoxal synthase [Escherichia coli 101-1], gi\|194421016\|gb\|EDX... gi\|193070068, gi... - gi\|193070068\|ref\|ZP_03051015.1\| methylglyoxal synthase [Escherichia coli E110019], gi\|192956665\|gb\|E... gi\|254591563, gi... - gi\|254792163\|ref\|YP_003077000.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. TW14359], gi\|... gi\|192925656, gi... - gi\|193066687\|ref\|ZP_03047717.1\| methylglyoxal synthase [Escherichia coli E22], gi\|192925656\|gb\|EDV80... gi\|191166598, gi... - gi\|191166598\|ref\|ZP_03028427.1\| methylglyoxal synthase [Escherichia coli B7A], gi\|190903403\|gb\|EDV63... MGSA_SHIFL - Methylglyoxal synthase OS=Shigella flexneri GN=mgsA PE=3 SV=1 EG12307 - methylglyoxal synthase / Methylglyoxal synthase	7.0E-71	[1..152]	[1..152]
gi\|82776254, gi\|... - gi\|82776254\|ref\|YP_402603.1\| methylglyoxal synthase [Shigella dysenteriae Sd197], gi\|81240402\|gb\|ABB... gi\|82544713, gi\|... - gi\|82544713\|ref\|YP_408660.1\| methylglyoxal synthase [Shigella boydii Sb227], gi\|81246124\|gb\|ABB66832... gi\|75190031 - gi\|75190031\|ref\|ZP_00703298.1\| COG1803: Methylglyoxal synthase [Escherichia coli E24377A] gi\|75195152 - gi\|75195152\|ref\|ZP_00705222.1\| COG1803: Methylglyoxal synthase [Escherichia coli HS] gi\|83584615 - gi\|83584615\|ref\|ZP_00923284.1\| COG1803: Methylglyoxal synthase [Escherichia coli 101-1] gi\|15830301, gi\|... - gi\|15830301\|ref\|NP_309074.1\| methylglyoxal synthase [Escherichia coli O157:H7 str. Sakai], gi\|133605... gi\|75175476 - gi\|75175476\|ref\|ZP_00695696.1\| COG1803: Methylglyoxal synthase [Shigella boydii BS512] gi\|75255125 - gi\|75255125\|ref\|ZP_00727012.1\| COG1803: Methylglyoxal synthase [Escherichia coli E22] gi\|74311520, gi\|... - gi\|74311520\|ref\|YP_309939.1\| methylglyoxal synthase [Shigella sonnei Ss046], gi\|73854997\|gb\|AAZ87704... gi\|75230238 - gi\|75230238\|ref\|ZP_00716735.1\| COG1803: Methylglyoxal synthase [Escherichia coli B7A] gi\|75235199 - gi\|75235199\|ref\|ZP_00719441.1\| COG1803: Methylglyoxal synthase [Escherichia coli E110019] gi\|124529145, gi... - gi\|124529145\|ref\|ZP_01700255.1\| methylglyoxal synthase [Escherichia coli B], gi\|124500100\|gb\|EAY4757... gi\|24051245, gi\|... - gi\|24112376\|ref\|NP_706886.1\| methylglyoxal synthase [Shigella flexneri 2a str. 301], gi\|24051245\|gb\|... gi\|209774384, gi... - gi\|7451073\|pir\|\|B64837 methylglyoxal synthase (EC 4.2.3.3) [similarity] - Escherichia coli (strain K... gi\|15830301, gi\|... - gi\|15830301\|ref\|NP_309074.1\| methylglyoxal synthase [Escherichia coli O157:H7], gi\|13360507\|dbj\|BAB3... gi\|30040748, gi\|... - gi\|30062502\|ref\|NP_836673.1\| methylglyoxal synthase [Shigella flexneri 2a str. 2457T], gi\|30040748\|g... gi\|15800822, gi\|... - gi\|15800822\|ref\|NP_286838.1\| methylglyoxal synthase [Escherichia coli O157:H7 EDL933], gi\|12514148\|g... gi\|16128930, gi\|... - dbj\|BAA35728.1\| Hypothetical protein in held 3'region . [Escherichia coli K12], gb\|AAC74049.1\| meth...	8.0E-71	[1..152]	[4..155]
gi\|77974894 - gi\|77974894\|ref\|ZP_00830432.1\| COG1803: Methylglyoxal synthase [Yersinia frederiksenii ATCC 33641]	1.0E-70	[1..152]	[27..178]
gi\|90413297, gi\|... - gi\|90413297\|ref\|ZP_01221291.1\| methylglyoxal synthase [Photobacterium profundum 3TCK], gi\|90325698\|g...	2.0E-70	[1..151]	[1..151]
MGSA_VIBVU - Methylglyoxal synthase OS=Vibrio vulnificus GN=mgsA PE=3 SV=1 MGSA_VIBVY - Methylglyoxal synthase OS=Vibrio vulnificus (strain YJ016) GN=mgsA PE=3 SV=1 MGSA_VIBVU - Methylglyoxal synthase OS=Vibrio vulnificus (strain CMCP6) GN=mgsA PE=3 SV=1	2.0E-70	[1..151]	[1..151]
gi\|194539096, gi... - gi\|75855948\|ref\|ZP_00763586.1\| COG1803: Methylglyoxal synthase [Vibrio sp. Ex25], gi\|254229815\|ref\|Z... gi\|91188321, gi\|... - gi\|91227912\|ref\|ZP_01262051.1\| methylglyoxal synthase [Vibrio alginolyticus 12G01], gi\|91188321\|gb\|E...	2.0E-70	[1..151]	[1..151]
gi\|83570629 - gi\|83570629\|ref\|ZP_00922073.1\| COG1803: Methylglyoxal synthase [Shigella dysenteriae 1012]	3.0E-70	[1..152]	[4..155]

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Predicted Domain #1

Region A:
Residues: [1-152]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELTTRTLPT RKHIALVAHD HCKQMLMNWV ERHQPLLEKH VLYATGTTGN LIQRATGMDV  60
   61 NAMLSGPMGG DQQVGALISE GKIDVLIFFW DPLNAVPHDP DVKALLRLAT VWNIPVATNV 120
  121 STADFIIQSP HFNDAVDILI PDYARYLAER LK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.221849
Match:	1b93A
Description:	Methylglyoxal synthase, MgsA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methylglyoxal synthase activity	7.67158041469211	bayes_pls_golite062009
catalytic activity	2.05174935916901	bayes_pls_golite062009
carbon-oxygen lyase activity	0.8193600732138	bayes_pls_golite062009
carbon-oxygen lyase activity, acting on phosphates	0.74427062677768	bayes_pls_golite062009
lyase activity	0.129701662862796	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: