YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|190407122
Organism:	Saccharomyces cerevisiae RM11-1a
Length:	897 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190407122.

Description	E-value	Query Range	Subject Range
ATG1_YEAS7 - Serine/threonine-protein kinase ATG1 OS=Saccharomyces cerevisiae (strain YJM789) GN=ATG1 PE=3 SV=1 ATG1 - Protein ser/thr kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targ... ATG1_YEAST - Serine/threonine-protein kinase ATG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATG... gi\|207345486 - gi\|207345486\|gb\|EDZ72296.1\| YGL180Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190407122 - gi\|190407122\|gb\|EDV10389.1\| protein kinase [Saccharomyces cerevisiae RM11-1a]	0.0	[1..897]	[1..897]
ATG1_PICAN - Serine/threonine-protein kinase ATG1 OS=Pichia angusta GN=ATG1 PE=3 SV=1 ATG1_PICAN - Serine/threonine-protein kinase ATG1 OS=Pichia angusta GN=ATG1 PE=3 SV=1	0.0	[14..896]	[3..800]
gi\|238031362, gi... - gi\|254568910\|ref\|XP_002491565.1\| Protein serine/threonine kinase required for vesicle formation in a... ATG1_PICPA - Serine/threonine-protein kinase ATG1 OS=Komagataella pastoris GN=ATG1 PE=3 SV=1 jgi\|Picpa1\|37626... - null	0.0	[17..893]	[2..787]
ppk36 - serine /threonine protein kinase Ppk36 ATG1_SCHPO - Serine/threonine-protein kinase atg1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=atg1 ...	0.0	[15..897]	[5..811]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[4..693]	[2..615]
gi\|9845487, gi\|1... - ref\|NP_059672.1\| MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens], gi\|1749794\|...	0.0	[4..693]	[2..615]
Atg1-PA - The gene Autophagy-specific gene 1 is referred to in FlyBase by the symbol Dmel\Atg1 (CG10967, FBgn0...	0.0	[21..891]	[4..824]
gi\|148225752, gi... - gi\|19698204\|dbj\|BAB86594.1\| serine/threonine kinase [Xenopus laevis], gi\|148225752\|ref\|NP_001080425....	0.0	[2..692]	[35..646]
gi\|3172111 - gi\|3172111\|dbj\|BAA28663.1\| HrPOPK-1 [Halocynthia roretzi]	0.0	[15..753]	[5..687]

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Predicted Domain #1

Region A:
Residues: [1-74]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDIKNKDHT TSVNHNLMAS AGNYTAEKEI GKGSFATVYR GHLTSDKSQH VAIKEVSRAK  60
   61 LKNKKLLENL EIEI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [88-104]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LIDCERTSTD FYLIMEY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	384.9794
Match:	1fotA_
Description:	cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [75-87]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AILKKIKHPH IVG

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [105-427]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CALGDLTFLL KRRKELMENH PLLRTVFEKY PPPSENHNGL HRAFVLSYLQ QLASALKFLR  60
   61 SKNLVHRDIK PQNLLLSTPL IGYHDSKSFH ELGFVGIYNL PILKIADFGF ARFLPNTSLA 120
  121 ETLCGSPLYM APEILNYQKY NAKADLWSVG TVVFEMCCGT PPFRASNHLE LFKKIKRAND 180
  181 VITFPSYCNI EPELKELICS LLTFDPAQRI GFEEFFANKV VNEDLSSYEL EDDLPELESK 240
  241 SKGIVESNMF VSEYLSKQPK SPNSNLAGHQ SMADNPAELS DALKNSNILT APAVKTDHTQ 300
  301 AVDKKASNNK YHNSLVSDRS FER

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	384.9794
Match:	1fotA_
Description:	cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [428-897]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYVVVEKKSV EVNSLADEVA QAGFNPNPIK HPTSTQNQNV LLNEQFSPNN QQYFQNQGEN  60
   61 PRLLRATSSS SGGSDGSRRP SLVDRRLSIS SLNPSNALSR ALGIASTRLF GGANQQQQQQ 120
  121 QITSSPPYSQ TLLNSQLFHE LTENIILRID HLQHPETLKL DNTNIVSILE SLAAKAFVVY 180
  181 SYAEVKFSQI VPLSTTLKGM ANFENRRSMD SNAIAEEQDS DDAEEEDETL KKYKEDCLST 240
  241 KTFGKGRTLS ATSQLSATFN KLPRSEMILL CNEAIVLYMK ALSILSKSMQ VTSNWWYESQ 300
  301 EKSCSLRVNV LVQWLREKFN ECLEKADFLR LKINDLRFKH ASEVAENQTL EEKGSSEEPV 360
  361 YLEKLLYDRA LEISKMAAHM ELKGENLYNC ELAYATSLWM LETSLDDDDF TNAYGDYPFK 420
  421 TNIHLKSNDV EDKEKYHSVL DENDRIIIRK YIDSIANRLK ILRQKMNHQN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [678-897]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATSQLSATFN KLPRSEMILL CNEAIVLYMK ALSILSKSMQ VTSNWWYESQ EKSCSLRVNV  60
   61 LVQWLREKFN ECLEKADFLR LKINDLRFKH ASEVAENQTL EEKGSSEEPV YLEKLLYDRA 120
  121 LEISKMAAHM ELKGENLYNC ELAYATSLWM LETSLDDDDF TNAYGDYPFK TNIHLKSNDV 180
  181 EDKEKYHSVL DENDRIIIRK YIDSIANRLK ILRQKMNHQN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits