YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|215446369
Organism:	Mycobacterium tuberculosis T85
Length:	448 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|215446369.

Description	E-value	Query Range	Subject Range
gi\|81253871 - gi\|81253871\|ref\|ZP_00878402.1\| COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desucci... gi\|123215699, gi... - gi\|76784027\|ref\|ZP_00771214.1\| COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desucci...	287.0	[0..2]	[448..8]
gi\|15827662 - gi\|15827662\|ref\|NP_301925.1\| hypothetical protein ML1288 [Mycobacterium leprae TN] gi\|13093213, gi\|... - pir\|\|B87070 probable peptidase [imported] - Mycobacterium leprae, gi\|13093213\|emb\|CAC31669.1\| possib... gi\|221230139, gi... - gi\|221230139\|ref\|YP_002503555.1\| putative peptidase [Mycobacterium leprae Br4923], gi\|219933246\|emb\|...	285.0	[0..13]	[448..32]
gi\|119695347, gi... - gi\|92915680\|ref\|ZP_01284303.1\| Peptidase M20:Peptidase dimerisation [Mycobacterium sp. KMS], gi\|9244... gi\|108800130, gi... - gi\|108800130\|ref\|YP_640327.1\| hypothetical protein Mmcs_3164 [Mycobacterium sp. MCS], gi\|108770549\|g...	277.0	[0..13]	[448..9]
gi\|126235555, gi... - gi\|92907914\|ref\|ZP_01276693.1\| Peptidase M20:Peptidase dimerisation [Mycobacterium sp. JLS], gi\|9243...	275.0	[0..13]	[448..9]
gi\|111017911, gi... - gi\|111017911\|ref\|YP_700883.1\| hypothetical protein RHA1_ro00892 [Rhodococcus jostii RHA1], gi\|110817...	274.0	[0..2]	[447..4]
gi\|54016387, gi\|... - gi\|54024879\|ref\|YP_119121.1\| hypothetical protein nfa29100 [Nocardia farcinica IFM 10152], gi\|540163...	272.0	[0..14]	[447..18]
gi\|41407984, gi\|... - gi\|41407984\|ref\|NP_960820.1\| hypothetical protein MAP1886c [Mycobacterium avium subsp. paratuberculo... gi\|254775022 - gi\|254775022\|ref\|ZP_05216538.1\| hypothetical protein MaviaA2_10159 [Mycobacterium avium subsp. avium... gi\|118163554, gi... - gi\|118462267\|ref\|YP_881553.1\| hypothetical protein MAV_2350 [Mycobacterium avium 104], gi\|118163554\|...	271.0	[0..1]	[448..1]
gi\|145223624, gi... - gi\|89339066\|ref\|ZP_01191831.1\| Peptidase M20:Peptidase dimerisation [Mycobacterium flavescens PYR-GC...	258.0	[0..13]	[447..16]
gi\|119957279, gi... - gi\|90206167\|ref\|ZP_01208803.1\| Peptidase M20:Peptidase dimerisation [Mycobacterium vanbaalenii PYR-1...	258.0	[0..20]	[447..2]
gi\|145594691, gi... - gi\|145594691\|ref\|YP_001158988.1\| hypothetical protein Strop_2159 [Salinispora tropica CNB-440], gi\|1...	257.0	[0..2]	[448..3]

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Predicted Domain #1

Region A:
Residues: [1-448]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDETGASSD HSDDVAQVVS RLIRFDTTNS GEPGTTKGEA ECARWVAEQL AEVGYQPEYV  60
   61 ESGAPGRGNV FARLAGADSS RGALLIHGHL DVVPAEPAEW SVHPFSGAIE DGYVWGRGAV 120
  121 DMKDMVGMMI VVARHLRQAA IVPPRDLVFA FVADEEHGGK YGSHWLVDNR PDLFDGITEA 180
  181 IGEVGGFSLT VPRHDGGERR LYLIETAEKG IQWMRLTARG RAGHGSMVHD QNAVTAVCEA 240
  241 VARLGRHQFP LVCTDTVAQF LAVVGEETGL AFDLDSPDLA GTIDKLGPMA RMLKAVLHDT 300
  301 ANPTMLKAGY KANVVPATAE AVVDCRVLPG RRAAFEAEVD ALIGPDVTRE WVSDLPSYET 360
  361 TFDGDLVAAM NAAVLAVDPD GRTVPYMLSG GTDAKAFARL GIRCFGFSPL RLPPDLDFTS 420
  421 LFHGVDERVP IDGLRFGTEV LTHLLTHC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.045757
Match:	1vgyA
Description:	Crystal structure of succinyl diaminopimelate desuccinylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	3.53599751822623	bayes_pls_golite062009
hydrolase activity	3.17104798571343	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	2.83557334423635	bayes_pls_golite062009
catalytic activity	2.00064748759729	bayes_pls_golite062009
exopeptidase activity	0.960517137038552	bayes_pls_golite062009
binding	0.456088952797852	bayes_pls_golite062009
carboxypeptidase activity	0.389857234977383	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: