YRC Public Data Repository - Protein Structure Prediction

Protein:	RPIA_ECO5E
Organism:	Escherichia coli O157:H7 str. EC4115
Length:	219 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPIA_ECO5E.

Description	E-value	Query Range	Subject Range
gi\|24114166, gi\|... - ref\|NP_708676.1\| ribose-5-phosphate isomerase, constitutive [Shigella flexneri 2a str. 301], gb\|AAN... gi\|26109738, gi\|... - gi\|26249330\|ref\|NP_755370.1\| ribose-5-phosphate isomerase A [Escherichia coli CFT073], gi\|26109738\|g... gi\|91212293, gi\|... - gi\|91212293\|ref\|YP_542279.1\| ribose-5-phosphate isomerase A [Escherichia coli UTI89], gi\|91073867\|gb... gi\|226899478, gi... - gi\|237706438\|ref\|ZP_04536919.1\| ribose-5-phosphate isomerase A [Escherichia sp. 3_2_53FAA], gi\|22689... gi\|226839585, gi... - gi\|254037961\|ref\|ZP_04872019.1\| ribose-5-phosphate isomerase A [Escherichia sp. 1_1_43], gi\|22683958...	266.0	[0..1]	[219..25]
gi\|94426307, gi\|... - gi\|94501489\|ref\|ZP_01308007.1\| ribose 5-phosphate isomerase A [Oceanobacter sp. RED65], gi\|94426307\|...	266.0	[0..1]	[218..1]
RPIA_NITEU - Ribose-5-phosphate isomerase A OS=Nitrosomonas europaea GN=rpiA PE=3 SV=1 RPIA_NITEU - Ribose-5-phosphate isomerase A OS=Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298) GN=rpiA PE=...	265.0	[0..1]	[218..1]
gi\|83587691 - gi\|83587691\|ref\|ZP_00926318.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli 101-1] gi\|42943 - gi\|42943\|emb\|CAA47309.1\| unnamed protein product [Escherichia coli] gi\|75178806 - gi\|75178806\|ref\|ZP_00698842.1\| COG0120: Ribose 5-phosphate isomerase [Shigella boydii BS512] gi\|75187629 - gi\|75187629\|ref\|ZP_00700896.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli E24377A] RPIA_ECOK1 - Ribose-5-phosphate isomerase A OS=Escherichia coli O1:K1 / APEC GN=rpiA PE=3 SV=1 gi\|75196865 - gi\|75196865\|ref\|ZP_00706935.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli HS] gi\|124526181, gi... - gi\|124526181\|ref\|ZP_01698186.1\| ribose 5-phosphate isomerase [Escherichia coli B], gi\|124502285\|gb\|E... gi\|227888463, gi... - gi\|227888463\|ref\|ZP_04006268.1\| ribose-5-phosphate isomerase A [Escherichia coli 83972], gi\|22783473... gi\|75212472 - gi\|75212472\|ref\|ZP_00712496.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli B171] gi\|75228581 - gi\|75228581\|ref\|ZP_00715210.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli B7A] gi\|75239518 - gi\|75239518\|ref\|ZP_00723489.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli E110019] gi\|75258513 - gi\|75258513\|ref\|ZP_00729935.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli E22]	264.0	[0..1]	[219..13]
gi\|75241290 - gi\|75241290\|ref\|ZP_00725152.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli F11]	263.0	[0..1]	[219..13]
lcl\|NC_016856.1_... - [gene=rpiA] [protein=ribose-5-phosphate isomerase A] [protein_id=YP_005239204.1] [location=complemen... RPIA_SALPB - Ribose-5-phosphate isomerase A OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=rpiA PE=3 ... gi\|213646130 - gi\|213646130\|ref\|ZP_03376183.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... gi\|213864991 - gi\|213864991\|ref\|ZP_03387110.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... gi\|214003525 - gi\|214003525\|ref\|ZP_03414260.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... RPIA_SALPC - Ribose-5-phosphate isomerase A OS=Salmonella paratyphi C (strain RKS4594) GN=rpiA PE=3 SV=1 RPIA_SALEP - Ribose-5-phosphate isomerase A OS=Salmonella enteritidis PT4 (strain P125109) GN=rpiA PE=3 SV=1 RPIA_SALTI - Ribose-5-phosphate isomerase A OS=Salmonella typhi GN=rpiA PE=3 SV=1 gi\|213162872 - gi\|213162872\|ref\|ZP_03348582.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... gi\|213427298 - gi\|213427298\|ref\|ZP_03360048.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... gi\|213613186 - gi\|213613186\|ref\|ZP_03371012.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... gi\|16761844 - gi\|16761844\|ref\|NP_457461.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ser... gi\|238909863 - gi\|238909863\|ref\|ZP_04653700.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ... RPIA_SALTY - Ribose-5-phosphate isomerase A OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=rp... RPIA_SALPK - Ribose-5-phosphate isomerase A OS=Salmonella paratyphi A (strain AKU_12601) GN=rpiA PE=3 SV=1 gi\|29143331, gi\|... - gi\|29143331\|ref\|NP_806673.1\| ribose-5-phosphate isomerase A [Salmonella enterica subsp. enterica ser... RPIA_SALG2 - Ribose-5-phosphate isomerase A OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=rpiA PE=3 SV... RPIA_SALCH - Ribose-5-phosphate isomerase A OS=Salmonella choleraesuis (strain SC-B67) GN=rpiA PE=3 SV=1 RPIA_SALPA - Ribose-5-phosphate isomerase A OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=rpiA PE=3 SV... RPIA_SALTY - Ribose-5-phosphate isomerase A OS=Salmonella typhimurium GN=rpiA PE=3 SV=1 RPIA_SALCH - Ribose-5-phosphate isomerase A OS=Salmonella choleraesuis GN=rpiA PE=3 SV=1 RPIA_SALPA - Ribose-5-phosphate isomerase A OS=Salmonella paratyphi A GN=rpiA PE=3 SV=1 RPIA_SALTI - Ribose-5-phosphate isomerase A OS=Salmonella typhi GN=rpiA PE=3 SV=1 RPIA_SALPB - Ribose-5-phosphate isomerase A OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=rpiA PE=3 ... RPIA_SALTY - Ribose-5-phosphate isomerase A OS=Salmonella typhimurium GN=rpiA PE=3 SV=1 RPIA_SALCH - Ribose-5-phosphate isomerase A OS=Salmonella choleraesuis GN=rpiA PE=3 SV=1	263.0	[0..1]	[219..1]
RPIA_SHESW - Ribose-5-phosphate isomerase A OS=Shewanella sp. (strain W3-18-1) GN=rpiA PE=3 SV=1	261.0	[0..1]	[218..1]
gi\|75515302 - gi\|75515302\|ref\|ZP_00737486.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli 53638]	261.0	[0..1]	[219..13]
RPIA_ENTCL - Ribose-5-phosphate isomerase A OS=Enterobacter cloacae GN=rpiA PE=3 SV=1	261.0	[0..1]	[219..1]
gi\|89081936, gi\|... - gi\|89093806\|ref\|ZP_01166752.1\| ribose 5-phosphate isomerase [Oceanospirillum sp. MED92], gi\|89081936...	261.0	[0..1]	[218..1]

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Predicted Domain #1

Region A:
Residues: [1-219]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQDELKKAV GWAALQYVQP GTIVGVGTGS TAAHFIDALG TMKGQIEGAV SSSDASTEKL  60
   61 KSLGIHVFDL NEVDSLGIYV DGADEINGHM QMIKGGGAAL TREKIIASVA EKFICIADAS 120
  121 KQVDILGKFP LPVEVIPMAR SAVARQLVKL GGRPEYRQGV VTDNGNVILD VHGMEILDPI 180
  181 AMENAINAIP GVVTVGLFAN RGADVALIGT PDGVKTIVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.69897
Match:	1ks2A
Description:	D-ribose-5-phosphate isomerase (RpiA), catalytic domain; D-ribose-5-phosphate isomerase (RpiA), lid domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribose-5-phosphate isomerase activity	2.23318567990318	bayes_pls_golite062009
6-phosphogluconolactonase activity	1.97756803122763	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.61058174487002	bayes_pls_golite062009
catalytic activity	0.424959044318554	bayes_pls_golite062009
nucleic acid binding	0.281224782944976	bayes_pls_golite062009
binding	0.228090098582514	bayes_pls_golite062009
glucosamine-6-phosphate deaminase activity	0.111185777194415	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	0.075853172283603	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: