YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213857775
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. M223
Length:	197 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213857775.

Description	E-value	Query Range	Subject Range
gi\|56129127, gi\|... - gi\|56414870\|ref\|YP_151945.1\| hypothetical protein SPA2778 [Salmonella enterica subsp. enterica serov... gi\|197095275, gi... - gi\|197363798\|ref\|YP_002143435.1\| hypothetical protein SSPA2590 [Salmonella enterica subsp. enterica ...	3.0E-67	[1..196]	[1..196]
gi\|205328721, gi... - gi\|205328721\|gb\|EDZ15485.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica subsp. e... gi\|168261951, gi... - gi\|205349076\|gb\|EDZ35707.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica subsp. e... lcl\|NC_016856.1_... - [gene=STM14_3523] [protein=putative flavoprotein] [protein_id=YP_005239032.1] [location=3083419..308... gi\|16766227, gi\|... - gi\|16766227\|ref\|NP_461842.1\| putative flavoprotein [Salmonella typhimurium LT2], gi\|16421470\|gb\|AAL2... gi\|199603741, gi... - gi\|200386643\|ref\|ZP_03213255.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica subs... gi\|194403613, gi... - gi\|194444950\|ref\|YP_002042162.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica sub... gi\|197262120, gi... - gi\|197262120\|ref\|ZP_03162194.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica subs...	3.0E-65	[1..197]	[1..197]
gi\|204928138, gi... - gi\|204928138\|ref\|ZP_03219338.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica subs... gi\|238909689 - gi\|238909689\|ref\|ZP_04653526.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica subs... gi\|197215278, gi... - gi\|197251575\|ref\|YP_002147816.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica sub... gi\|194736013, gi... - gi\|194736013\|ref\|YP_002115870.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica sub... gi\|194468535, gi... - gi\|194468535\|ref\|ZP_03074519.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica subs... gi\|62129054, gi\|... - gi\|62181421\|ref\|YP_217838.1\| putative flavoprotein [Salmonella enterica subsp. enterica serovar Chol... gi\|205342834, gi... - gi\|205342834\|gb\|EDZ29598.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica subsp. e... gi\|195633387, gi... - gi\|195633387\|gb\|EDX51801.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica subsp. e... gi\|197290760, gi... - gi\|197290760\|gb\|EDY30114.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica subsp. e... gi\|168230995, gi... - gi\|205334460\|gb\|EDZ21224.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica subsp. e... gi\|205324841, gi... - gi\|205324841\|gb\|EDZ12680.1\| 4-hydroxybenzoate decarboxylase, subunit B [Salmonella enterica subsp. e...	3.0E-65	[1..197]	[1..197]
gi\|168774728, gi... - gi\|187769605\|gb\|EDU33449.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7 str... gi\|189362054, gi... - gi\|189362054\|gb\|EDU80473.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7 str... gi\|189372223, gi... - gi\|189372223\|gb\|EDU90639.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7 str... gi\|168778722, gi... - gi\|189003454\|gb\|EDU72440.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7 str... gi\|168749935, gi... - gi\|188015767\|gb\|EDU53889.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7 str... gi\|168762861, gi... - gi\|189366873\|gb\|EDU85289.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7 str... gi\|189357352, gi... - gi\|189357352\|gb\|EDU75771.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7 str... gi\|15832847, gi\|... - gi\|15832847\|ref\|NP_311620.1\| putative phenylacrylic acid decarboxylase [Escherichia coli O157:H7 str... gi\|209159006, gi... - gi\|209397606\|ref\|YP_002272202.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H... gi\|208820709, gi... - gi\|208820709\|ref\|ZP_03261029.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7... gi\|217327877, gi... - gi\|217327877\|ref\|ZP_03443960.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7... gi\|25299158, gi\|... - gi\|4887557\|emb\|CAB43500.1\| phenylacrylic acid decarboxylase-like protein [Escherichia coli], pir\|\|A9... gi\|195938490 - gi\|195938490\|ref\|ZP_03083872.1\| putative phenylacrylic acid decarboxylase [Escherichia coli O157:H7 ... PADL_ECO57 - Probable UbiX-like flavin prenyltransferase OS=Escherichia coli O157:H7 GN=ecdB PE=1 SV=1 gi\|168800180, gi... - gi\|189377463\|gb\|EDU95879.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7 str... gi\|208734592, gi... - gi\|208813315\|ref\|ZP_03254644.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7... gi\|208728143, gi... - gi\|208808342\|ref\|ZP_03250679.1\| 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7... gi\|254794679, gi... - gi\|254794679\|ref\|YP_003079516.1\| putative decarboxylase [Escherichia coli O157:H7 str. TW14359], gi\|...	6.0E-64	[1..196]	[1..196]
gi\|81242254, gi\|... - gi\|82778106\|ref\|YP_404455.1\| phenylacrylic acid decarboxylase-like protein [Shigella dysenteriae Sd1...	9.0E-64	[1..196]	[1..196]
gi\|25299162 - gi\|25299162\|pir\|\|B85923 probable decarboxylase Z4047 [imported] - Escherichia coli (strain O157:H7,... gi\|15803256, gi\|... - gi\|15803256\|ref\|NP_289288.1\| putative decarboxylase [Escherichia coli O157:H7 EDL933], gi\|12517190\|g...	1.0E-63	[1..196]	[1..196]
gi\|194431624, gi... - gi\|194431624\|ref\|ZP_03063915.1\| 4-hydroxybenzoate decarboxylase, subunit B [Shigella dysenteriae 101... gi\|218362055, gi... - gi\|218555287\|ref\|YP_002388200.1\| conserved putative non-oxidative reversible hydroxyarylic acid deca... gi\|209913441, gi... - gi\|209920182\|ref\|YP_002294266.1\| putative phenylacrylic acid decarboxylase [Escherichia coli SE11], ... gi\|218696337, gi... - gi\|218696337\|ref\|YP_002404004.1\| conserved putative non-oxidative reversible hydroxyarylic acid deca... gi\|24053156, gi\|... - gi\|24114034\|ref\|NP_708544.1\| phenylacrylic acid decarboxylase-like protein [Shigella flexneri 2a str... gi\|30042353, gi\|... - gi\|30064097\|ref\|NP_838268.1\| phenylacrylic acid decarboxylase-like protein [Shigella flexneri 2a str... gi\|193064989, gi... - gi\|75256945\|ref\|ZP_00728521.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|190903175, gi... - gi\|75230050\|ref\|ZP_00716560.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... PADL_ECOLX - Probable UbiX-like flavin prenyltransferase OS=Escherichia coli GN=ecdB PE=3 SV=1	2.0E-63	[1..196]	[1..196]
gi\|194414086, gi... - gi\|75210945\|ref\|ZP_00711069.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|10197690 - gi\|10197690\|gb\|AAG14973.1\|AF242208_6 phenylacrylic acid decarboxylase-like protein [Escherichia coli... PADL_ECO11 - Probable UbiX-like flavin prenyltransferase OS=Escherichia coli O111:H- GN=ecdB PE=3 SV=1	3.0E-63	[1..196]	[1..196]
gi\|157157116, gi... - gi\|75187467\|ref\|ZP_00700734.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co...	4.0E-63	[1..196]	[1..196]
gi\|110616178, gi... - gi\|110806630\|ref\|YP_690150.1\| phenylacrylic acid decarboxylase-like protein [Shigella flexneri 5 str...	4.0E-63	[1..196]	[1..196]

Back

Predicted Domain #1

Region A:
Residues: [1-197]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLIVGMTGA TGAPLGVELL QALRAIPDVE THLVMSKWAK TTIELETPYT PAEVAALADY  60
   61 CHSPADQAAT ISSGSFRTDG MIIIPCSMKT LAGVRAGYAD GLVGRAADVV LKEGRKLVLV 120
  121 PREMPLSTIH LENMLALSRM GVAIVPPMPA FYNLPQTVDD IIQHIVARVL DQFGLEHTRA 180
  181 RRWQGLRQAA NFSQENG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.39794
Match:	1sbzA
Description:	Crystal Structure of dodecameric FMN-dependent Ubix-like Decarboxylase from Escherichia coli O157:H7
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	5.88631349530005	bayes_pls_golite062009
carboxy-lyase activity	2.27469953971238	bayes_pls_golite062009
catalytic activity	1.88716391063227	bayes_pls_golite062009
carbon-carbon lyase activity	1.67751595868044	bayes_pls_golite062009
phosphopantothenoylcysteine decarboxylase activity	1.6488492075417	bayes_pls_golite062009
lyase activity	0.646446561158526	bayes_pls_golite062009
phosphopantothenate--cysteine ligase activity	0.35505046579356	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: