YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|218901537, gi...
Organism:	Bacillus cereus AH820
Length:	348 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|218901537, gi....

Description	E-value	Query Range	Subject Range
gi\|52144901, gi\|... - gi\|52144901\|ref\|YP_081928.1\| translation initiation factor IF-2B subunit alpha [Bacillus cereus E33L...	0.0	[1..347]	[1..347]
MTNA1_BACAN - Methylthioribose-1-phosphate isomerase 1 OS=Bacillus anthracis GN=mtnA1 PE=3 SV=1 MTNA1_BACAH - Methylthioribose-1-phosphate isomerase 1 OS=Bacillus thuringiensis (strain Al Hakam) GN=mtnA1 PE=3 S... gi\|254724807 - gi\|254724807\|ref\|ZP_05186590.1\| methylthioribose-1-phosphate isomerase [Bacillus anthracis str. A105... gi\|254761928 - gi\|254761928\|ref\|ZP_05213777.1\| methylthioribose-1-phosphate isomerase [Bacillus anthracis str. Aust... gi\|47500762, gi\|... - gi\|47525614\|ref\|YP_016963.1\| translation initiation factor IF-2B subunit alpha [Bacillus anthracis s... gi\|30260517, gi\|... - gi\|30260517\|ref\|NP_842894.1\| translation initiation factor IF-2B subunit alpha [Bacillus anthracis s... gi\|254739045 - gi\|254739045\|ref\|ZP_05196747.1\| methylthioribose-1-phosphate isomerase [Bacillus anthracis str. West... gi\|21398293 - ref\|NP_654278.1\| IF-2B, Initiation factor 2 subunit family [Bacillus anthracis str. A2012] gi\|254756110 - gi\|254756110\|ref\|ZP_05208139.1\| methylthioribose-1-phosphate isomerase [Bacillus anthracis str. Voll...	0.0	[2..348]	[1..347]
gi\|229143124, gi... - gi\|229143124\|ref\|ZP_04271556.1\| Translation initiation factor, aIF-2BI [Bacillus cereus BDRD-ST24], ... gi\|228657489, gi... - gi\|229125831\|ref\|ZP_04254856.1\| Translation initiation factor, aIF-2BI [Bacillus cereus BDRD-Cer4], ... gi\|228675404, gi... - gi\|229108004\|ref\|ZP_04237630.1\| Translation initiation factor, aIF-2BI [Bacillus cereus Rock1-15], g... gi\|30018587, gi\|... - gi\|30018587\|ref\|NP_830218.1\| translation initiation factor IF-2B subunit alpha [Bacillus cereus ATCC...	0.0	[1..348]	[1..348]
gi\|163938337, gi... - gi\|89204755\|ref\|ZP_01183331.1\| Putative translation initiation factor, aIF-2BI:Initiation factor 2B ...	0.0	[1..348]	[1..348]
gi\|49480064, gi\|... - gi\|49480064\|ref\|YP_034666.1\| translation initiation factor IF-2B subunit alpha [Bacillus thuringiens...	0.0	[1..348]	[1..348]
gi\|47569401, gi\|... - gi\|47569401\|ref\|ZP_00240083.1\| translation initiation factor, putative, aIF-2BI family [Bacillus cer...	0.0	[2..348]	[1..347]
MTNA_GEOMG - Methylthioribose-1-phosphate isomerase OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM...	0.0	[7..348]	[4..345]
MTNA_GEOSL - Methylthioribose-1-phosphate isomerase OS=Geobacter sulfurreducens GN=mtnA PE=3 SV=1 MTNA_GEOSL - Methylthioribose-1-phosphate isomerase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / ...	0.0	[7..346]	[4..343]
gi\|218895455, gi... - gi\|218895455\|ref\|YP_002443866.1\| putative translation initiation factor, aIF-2BI family [Bacillus ce... gi\|74492082, gi\|... - gi\|75760433\|ref\|ZP_00740475.1\| Methylthioribose salvage protein [Bacillus thuringiensis serovar isra... gi\|228963437, gi... - gi\|228963437\|ref\|ZP_04124597.1\| Translation initiation factor, aIF-2BI [Bacillus thuringiensis serov... gi\|228854417, gi... - gi\|228905217\|ref\|ZP_04069211.1\| Translation initiation factor, aIF-2BI [Bacillus thuringiensis IBL 4...	0.0	[1..348]	[1..348]
MTNA_THEMA - Methylthioribose-1-phosphate isomerase OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 /... MTNA_THEMA - Methylthioribose-1-phosphate isomerase OS=Thermotoga maritima GN=mtnA PE=1 SV=1	0.0	[2..348]	[1..342]

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Predicted Domain #1

Region A:
Residues: [1-348]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMEEQLIPIQ WKDDALVLLD QTLLPNEVVY ESFNTAEGVW DAIQVMKVRG APAIGVSAAY  60
   61 GVYLGVKEFV ESTEAEFIDE VKRVCAYLAT SRPTAVNLFW ALERMESVAT DHTHLSITQL 120
  121 KDRLLEEAKE IHREDEEINR QIGEHALTLF HDGMGVLTHC NAGALATTKY GTATAPMYLA 180
  181 KEKGWDLKIY SDETRPRLQG STLTALELQR AGIDVTVITD NMAAMVMSQG KIDAVIVGCD 240
  241 RVAANGDVAN KIGTLGVSIL AKYYNIPFYV AAPTPTIDLK TPTGKEIPIE ERDASEVINR 300
  301 FGQYSAPKES KVYNPAFDVT PHENVTAIIT EKGIVKAPFT ENLKKLFQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	122.0
Match:	1t9kA
Description:	X-ray crystal structure of aIF-2B alpha subunit-related translation initiation factor [Thermotoga maritima]
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation initiation factor activity	10.1099993541596	bayes_pls_golite062009
translation regulator activity	5.74669335554405	bayes_pls_golite062009
nucleic acid binding	2.17718456512191	bayes_pls_golite062009
transcription regulator activity	1.9283980201455	bayes_pls_golite062009
DNA binding	1.55389679363348	bayes_pls_golite062009
binding	1.53908996868286	bayes_pls_golite062009
transferase activity, transferring sulfur-containing groups	1.40526340076289	bayes_pls_golite062009
catalytic activity	1.31732715713197	bayes_pls_golite062009
translation factor activity, nucleic acid binding	1.09424756417577	bayes_pls_golite062009
transcription factor activity	0.995059566132783	bayes_pls_golite062009
deaminase activity	0.518630450774121	bayes_pls_golite062009
S-methyl-5-thioribose-1-phosphate isomerase activity	0.511292518421556	bayes_pls_golite062009
protein binding	0.0293610121675921	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: