YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|46014882, gi\|...
Organism:	Homo sapiens
Length:	146 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|46014882, gi|....

Description	E-value	Query Range	Subject Range
gi\|211464 - gi\|211464\|gb\|AAA48668.1\| c-ets protein	208.0	[0..2]	[146..347]
gi\|76657366 - gi\|76657366\|ref\|XP_871011.1\| PREDICTED: hypothetical protein isoform 2 [Bos taurus]	207.0	[0..2]	[146..341]
gi\|109109238 - gi\|109109238\|ref\|XP_001113071.1\| PREDICTED: v-ets erythroblastosis virus E26 oncogene homolog 1 isof...	206.0	[0..2]	[146..341]
gi\|60654163 - gi\|60654163\|gb\|AAX29774.1\| v-ets erythroblastosis virus E26 oncogene-like 1 [synthetic construct]	206.0	[0..2]	[146..297]
ETS1 - v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) HGNC:3488\|MIM:16... - erythroblastosis virus E26 oncogene homolog 1 (avian) gi\|61357895, gi\|... - gi\|61363075\|gb\|AAX42330.1\| v-ets erythroblastosis virus E26 oncogene-like 1 [synthetic construct], g...	206.0	[0..2]	[146..297]

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Predicted Domain #1

Region A:
Residues: [1-146]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNHKPKGTFK DYVRDRADLN KDKPVIPAAA LAGYTGSGPI QLWQFLLELL TDKSCQSFIS  60
   61 WTGDGWEFKL SDPDEVARRW GKRKNKPKMN YEKLSRGLRY YYDKNIIHKT AGKRYVYRFV 120
  121 CDLQSLLGYT PEELHAMLDV KPDADE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.221849
Match:	1gvjA
Description:	ETS-1 DNA BINDING AND AUTOINHIBITORY DOMAINS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.835523092977445	bayes_pls_golite062009
transcription regulator activity	0.4843036104266	bayes_pls_golite062009
nucleic acid binding	0.37117756729668	bayes_pls_golite062009
DNA binding	0.3118855114645	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: