YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|183569978, gi...
Organism:	Streptococcus pneumoniae CDC1087-00
Length:	330 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|183569978, gi....

Description	E-value	Query Range	Subject Range
gi\|15903827, gi\|... - gi\|15903827\|ref\|NP_359377.1\| asparagine synthetase AsnA [Streptococcus pneumoniae R6], gi\|15459469\|g... gi\|25293479 - gi\|25293479\|pir\|\|G98094 aspartate-ammonia ligase (EC 6.3.1.1) [imported] - Streptococcus pneumoniae ...	626.0	[0..1]	[330..3]
ASNA_ACTPJ - Aspartate--ammonia ligase OS=Actinobacillus pleuropneumoniae serotype 3 (strain JL03) GN=asnA PE=3 S... ASNA_ACTP7 - Aspartate--ammonia ligase OS=Actinobacillus pleuropneumoniae serotype 7 (strain AP76) GN=asnA PE=3 S... gi\|46143487 - gi\|46143487\|ref\|ZP_00135167.2\| COG2502: Asparagine synthetase A [Actinobacillus pleuropneumoniae ser... ASNA_ACTP2 - Aspartate--ammonia ligase OS=Actinobacillus pleuropneumoniae serotype 5b (strain L20) GN=asnA PE=3 S...	626.0	[0..1]	[330..1]
gi\|53733087 - gi\|53733087\|ref\|ZP_00155556.2\| COG2502: Asparagine synthetase A [Haemophilus influenzae R2846] gi\|145269342, gi... - gi\|145637396\|ref\|ZP_01793055.1\| asparagine synthetase AsnA [Haemophilus influenzae PittHH], gi\|14526...	625.0	[0..1]	[330..1]
ASNA_HAEI8 - Aspartate--ammonia ligase OS=Haemophilus influenzae (strain 86-028NP) GN=asnA PE=3 SV=1	623.0	[0..1]	[330..1]
gi\|145272122, gi... - gi\|145638527\|ref\|ZP_01794136.1\| ribulose-phosphate 3-epimerase [Haemophilus influenzae PittII], gi\|1... gi\|53733329 - gi\|53733329\|ref\|ZP_00156382.2\| COG2502: Asparagine synthetase A [Haemophilus influenzae R2866]	623.0	[0..1]	[330..1]
ASNA_HAEIN - Aspartate--ammonia ligase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=a... gi\|145640538, gi... - gi\|145640538\|ref\|ZP_01796122.1\| asparagine synthetase AsnA [Haemophilus influenzae R3021], gi\|144982... gi\|145640538, gi... - gi\|145640538\|ref\|ZP_01796122.1\| asparagine synthetase AsnA [Haemophilus influenzae R3021], gi\|145631... ASNA_HAEIN - Aspartate--ammonia ligase OS=Haemophilus influenzae GN=asnA PE=3 SV=1	622.0	[0..1]	[330..1]
ASNA_STRA1 - Aspartate--ammonia ligase OS=Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS... ASNA_STRA5 - Aspartate--ammonia ligase OS=Streptococcus agalactiae serotype V GN=asnA PE=3 SV=1 ASNA_STRA1 - Aspartate--ammonia ligase OS=Streptococcus agalactiae serotype Ia GN=asnA PE=3 SV=1 ASNA_STRA5 - Aspartate--ammonia ligase OS=Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R) GN...	620.0	[0..1]	[330..1]
ASNA_HAEDU - Aspartate--ammonia ligase OS=Haemophilus ducreyi GN=asnA PE=3 SV=1 ASNA_HAEDU - Aspartate--ammonia ligase OS=Haemophilus ducreyi (strain 35000HP / ATCC 700724) GN=asnA PE=3 SV=1	619.0	[0..1]	[330..1]
ASNA_STRA3 - Aspartate--ammonia ligase OS=Streptococcus agalactiae serotype III (strain NEM316) GN=asnA PE=3 SV=1 ASNA_STRA3 - Aspartate--ammonia ligase OS=Streptococcus agalactiae serotype III GN=asnA PE=3 SV=1	619.0	[0..1]	[330..1]

Back

Predicted Domain #1

Region A:
Residues: [1-330]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKSFIHQQE EISFVKNTFT QYLKDKLEVV EVQGPILSKV GDGMQDNLSG VENPVSVKVL  60
   61 QIPDATYEVV HSLAKWKRHT LARFGFGEGE GLFVHMKALR PDEDSLDATH SVYVDQWDWE 120
  121 KVIPNGKRNI VYLKETVEKI YKAIRLTELA VEARYDIESI LPKQITFIHT EELVERYPDL 180
  181 TPKERENAIC KEFGAVFLIG IGGELPDGKP HDGRAPDYDD WTSESENGYK GLNGDILVWN 240
  241 ESLGGAFELS SMGIRVDEET LRRQVEITGD EDRLELEWHK SLLNGLFPLT IGGGIGQSRM 300
  301 AMFLLRKRHI GEVQTSVWPQ EVRDTYENIL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	170.0
Match:	11asA
Description:	Asparagine synthetase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-oxygen bonds	3.95982081475525	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	3.95982081475525	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	3.9592004812151	bayes_pls_golite062009
ligase activity	3.05852492533937	bayes_pls_golite062009
catalytic activity	2.36416267096403	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	0.27932659689192	bayes_pls_golite062009
serine-tRNA ligase activity	0.15245558407217	bayes_pls_golite062009
threonine-tRNA ligase activity	0.0873863095068197	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: