YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|188014201, gi...
Organism:	Escherichia coli O157:H7 str. EC4113
Length:	190 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|188014201, gi....

Description	E-value	Query Range	Subject Range
gi\|82545714, gi\|... - gi\|82545714\|ref\|YP_409661.1\| peptidyl-prolyl cis-trans isomerase A (rotamase A) [Shigella boydii Sb2...	228.0	[0..1]	[190..1]
gi\|191168407, gi... - gi\|75228404\|ref\|ZP_00715050.1\| COG0652: Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin...	227.0	[0..1]	[190..1]
gi\|81242792, gi\|... - gi\|82778644\|ref\|YP_404993.1\| peptidyl-prolyl cis-trans isomerase A (rotamase A) [Shigella dysenteria...	227.0	[0..1]	[190..1]
gi\|110807197, gi... - gi\|110807197\|ref\|YP_690717.1\| peptidyl-prolyl cis-trans isomerase A (rotamase A) [Shigella flexneri ... gi\|24114628, gi\|... - gi\|24114628\|ref\|NP_709138.1\| peptidyl-prolyl cis-trans isomerase A (rotamase A) [Shigella flexneri 2... gi\|30065351, gi\|... - gi\|30065351\|ref\|NP_839522.1\| peptidyl-prolyl cis-trans isomerase A (rotamase A) [Shigella flexneri 2...	224.0	[0..1]	[190..1]
gi\|51317463 - gi\|51317463\|gb\|AAT99909.1\| TRIM5/cyclophilin A V4 fusion protein [Aotus trivirgatus]	218.0	[0..23]	[189..308]
gi\|77165714, gi\|... - gi\|77165714\|ref\|YP_344239.1\| peptidylprolyl isomerase [Nitrosococcus oceani ATCC 19707], gi\|76884028... gi\|207089446 - gi\|207089446\|gb\|EDZ66717.1\| peptidyl-prolyl cis-trans isomerase, cyclophilin-type, putative [Nitroso... gi\|254433113, gi... - gi\|254433113\|ref\|ZP_05046621.1\| peptidyl-prolyl cis-trans isomerase, cyclophilin-type, putative [Nit...	217.0	[0..3]	[189..6]
gi\|36783824, gi\|... - gi\|37524400\|ref\|NP_927744.1\| peptidyl-prolyl cis-trans isomerase A (rotamase A) [Photorhabdus lumine...	216.0	[0..1]	[190..1]
gi\|49613517, gi\|... - gi\|50122991\|ref\|YP_052158.1\| peptidyl-prolyl cis-trans isomerase A (rotamase A) [Pectobacterium atro...	213.0	[0..1]	[190..1]
gi\|83779024 - gi\|83779024\|gb\|ABC47329.1\| cyclophilin B precursor [Orpinomyces sp. PC-2]	212.0	[0..6]	[190..7]

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Predicted Domain #1

Region A:
Residues: [1-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKSTLAAMA AVFALSALSP AAMAAKGDPH VLLTTSAGNI ELELDKQKAP VSVQNFVDYV  60
   61 NSGFYNNTTF HRVIPGFMIQ GGGFTEQMQQ KKPNPPIKNE ADNGLRNTRG TIAMARTADK 120
  121 DSATSQFFIN VADNAFLDHG QRDFGYAVFG KVVKGMDVAD KISQVPTHDV GPYQNVPSKP 180
  181 VVILSAKVLP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.221849
Match:	1j2aA
Description:	Structure of E. coli cyclophilin B K163T mutant
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidyl-prolyl cis-trans isomerase activity	3.73853378771688	bayes_pls_golite062009
cis-trans isomerase activity	3.66963215732405	bayes_pls_golite062009
RNA binding	2.94609837984526	bayes_pls_golite062009
isomerase activity	1.96529188741504	bayes_pls_golite062009
binding	1.46018233647024	bayes_pls_golite062009
mRNA binding	1.45537055700871	bayes_pls_golite062009
unfolded protein binding	1.38124355054041	bayes_pls_golite062009
nucleic acid binding	0.939772862764466	bayes_pls_golite062009
catalytic activity	0.748655649755714	bayes_pls_golite062009
hydrolase activity	0.363074952403273	bayes_pls_golite062009
protein binding	0.130251391659493	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: