YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|167467890
Organism:	Yersinia pestis FV-1
Length:	243 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|167467890.

Description	E-value	Query Range	Subject Range
gi\|255744397\|ref... - peroxiredoxin family protein/glutaredoxin [Vibrio cholera CIRS 101] gi\|75827887 - gi\|75827887\|ref\|ZP_00757322.1\| COG0678: Peroxiredoxin [Vibrio cholerae O395] tr\|A0A085R3Z6\|A0... - Hybrid peroxiredoxin hyPrx5 OS=Vibrio cholerae GN=DN30_1754 PE=4 SV=1 gi\|75830057, gi\|... - gi\|75830057\|ref\|ZP_00759342.1\| COG0678: Peroxiredoxin [Vibrio cholerae MO10], gi\|116190632\|ref\|ZP_01... gi\|116219574, gi... - gi\|75818991\|ref\|ZP_00749098.1\| COG0678: Peroxiredoxin [Vibrio cholerae V51], gi\|116219574\|ref\|ZP_014... gi\|262158493\|ref... - peroxiredoxin family protein/glutaredoxin [Vibrio cholerae INDRE 91/1] gi\|75822900, gi\|... - gi\|75822900\|ref\|ZP_00752452.1\| COG0678: Peroxiredoxin [Vibrio cholerae RC385], gi\|116216129\|ref\|ZP_0... gi\|75816566 - gi\|75816566\|ref\|ZP_00747032.1\| COG0678: Peroxiredoxin [Vibrio cholerae V52] gi\|262170114\|ref... - peroxiredoxin family protein/glutaredoxin [Vibrio cholerae RC27]	8.0E-46	[1..238]	[1..238]
gi\|153213977, gi... - gi\|153213977\|ref\|ZP_01949170.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae 1587], gi... gi\|121630083, gi... - gi\|121727592\|ref\|ZP_01680700.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae V52], gi\|... gi\|254846881, gi... - gi\|254851176\|ref\|ZP_05240526.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae MO10], gi... gi\|229345953, gi... - gi\|229516890\|ref\|ZP_04406336.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae RC9], gi\|... gi\|153224207, gi... - gi\|153224207\|ref\|ZP_01954293.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae MAK 757],... gi\|229369472, gi... - gi\|229606817\|ref\|YP_002877465.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae MJ-1236]... gi\|126510002, gi... - gi\|153819461\|ref\|ZP_01972128.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae NCTC 8457... gi\|194537404, gi... - gi\|254225383\|ref\|ZP_04918994.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae V51], gi\|... gi\|229509765, gi... - gi\|229509765\|ref\|ZP_04399246.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae B33], gi\|... gi\|254285832, gi... - gi\|254285832\|ref\|ZP_04960794.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae AM-19226]... gi\|194536460, gi... - gi\|254222313\|ref\|ZP_04916185.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae RC385], g... gi\|153825079, gi... - gi\|153825079\|ref\|ZP_01977746.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae MZO-2], g... gi\|227119075, gi... - gi\|227119075\|ref\|YP_002820971.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae O395], g... gi\|227082753, gi... - gi\|227082753\|ref\|YP_002811304.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae M66-2], ... gi\|9657228, gi\|1... - gi\|9657228\|gb\|AAF95778.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae O1 biovar El To... gi\|229507311, gi... - gi\|229507311\|ref\|ZP_04396816.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae BX 330286... gi\|11355792 - pir\|\|D82051 peroxiredoxin family protein/glutaredoxin VC2637 [imported] - Vibrio cholerae (strain N1... gi\|121587911, gi... - gi\|121587911\|ref\|ZP_01677666.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae 2740-80],...	1.0E-45	[1..238]	[5..242]
gi\|112822227, gi... - gi\|113460184\|ref\|YP_718241.1\| peroxiredoxin [Haemophilus somnus 129PT], gi\|112822227\|gb\|ABI24316.1\| ...	3.0E-45	[7..242]	[3..238]
gi\|46156414, gi\|... - gi\|46156414\|ref\|ZP_00132875.2\| COG0678: Peroxiredoxin [Haemophilus somnus 2336], gi\|170718219\|ref\|YP... gi\|23467482 - gi\|23467482\|ref\|ZP_00123063.1\| COG0678: Peroxiredoxin [Haemophilus somnus 129PT]	4.0E-45	[7..242]	[5..240]
gi\|91188685, gi\|... - gi\|91227291\|ref\|ZP_01261716.1\| peroxiredoxin family protein/glutaredoxin [Vibrio alginolyticus 12G01...	1.0E-44	[1..241]	[1..241]
gi\|197316253, gi... - gi\|197334763\|ref\|YP_002157095.1\| hybrid peroxiredoxin hyPrx5 (Thioredoxin reductase) [Vibrio fischer... gi\|59712907, gi\|... - gi\|59712907\|ref\|YP_205683.1\| glutaredoxin [Vibrio fischeri ES114], gi\|59481008\|gb\|AAW86795.1\| glutar...	1.0E-44	[1..242]	[1..242]
gi\|33151875, gi\|... - gi\|33151875\|ref\|NP_873228.1\| putative peroxiredoxin/glutaredoxin family protein [Haemophilus ducreyi...	1.0E-44	[7..242]	[8..243]
gi\|75911177, gi\|... - gi\|75911177\|ref\|YP_325473.1\| glutaredoxin-like region [Anabaena variabilis ATCC 29413], gi\|75704902\|...	2.0E-44	[1..243]	[1..243]
gi\|238794892, gi... - gi\|77976811\|ref\|ZP_00832281.1\| COG0678: Peroxiredoxin [Yersinia intermedia ATCC 29909], gi\|238794892...	2.0E-44	[1..243]	[1..243]
gi\|32034501 - gi\|32034501\|ref\|ZP_00134673.1\| COG0678: Peroxiredoxin [Actinobacillus pleuropneumoniae serovar 1 str...	2.0E-44	[7..242]	[8..243]

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Predicted Domain #1

Region A:
Residues: [1-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFTSQEGKKV PQVTFHTRQG DQWIDVTTDD LFSNKTVIVF SLPGAFTPTC SSSHLPRYNE  60
   61 LAGVFKQHGV DSILCVSVND TFVMNAWKSD QHAENITFVP DGNGEFTKGM NMLVEKADLG 120
  121 FGPRSWRYSM LVRNGVVEKM FVEPNKPGDP FEVSDADTML KYLAPDFKVQ ESVAVFTKPG 180
  181 CPFCAKAKQM LQDHGLQYEE IVLGKDATTV SLRAVSGRST VPQIFIGGRH IGGSDDLEKY 240
  241 LPA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.69897
Match:	1nm3A
Description:	C-terminal, Grx domain of Hybrid-Prx5; N-terminal, Prx domain of Hybrid-Prx5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	3.66884588063322	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.8187537496904	bayes_pls_golite062009
protein disulfide oxidoreductase activity	1.47769936616412	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
binding	1.25802922431343	bayes_pls_golite062009
selenium binding	1.1082524159827	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
transcription regulator activity	0.52671047749426	bayes_pls_golite062009
protein binding	0.134341907247724	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: