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View Structure Prediction Details

Protein: gi|34810361, gi|...
Organism: Homo sapiens
Length: 167 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|34810361, gi|....

Description E-value Query
Range		 Subject
Range
CASP2_RAT - Caspase-2 OS=Rattus norvegicus GN=Casp2 PE=1 SV=3
 206.0 [0..1] [167..167]
gi|73978459 - gi|73978459|ref|XP_848601.1| PREDICTED: similar to caspase 2 isoform 1 preproprotein isoform 2 [Cani...
 206.0 [0..1] [167..167]
gi|26334905 - gi|26334905|dbj|BAC31153.1| unnamed protein product [Mus musculus]
 205.0 [0..1] [167..167]
gi|114616493 - gi|114616493|ref|XP_519448.2| PREDICTED: caspase 2 isoform 4 [Pan troglodytes]
CASP2 - caspase 2, apoptosis-related cysteine peptidase
 205.0 [0..1] [167..167]
gi|114616491 - gi|114616491|ref|XP_001162422.1| PREDICTED: caspase 2 isoform 3 [Pan troglodytes]
 205.0 [0..1] [167..154]

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Predicted Domain #1
Region A:
Residues: [1-167] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKDGPVCLQV KPCTPEFYQT HFQLAYRLQS RPRGLALVLS NVHFTGEKEL EFRSGGDVDH  60
   61 STLVTLFKLL GYDVHVLCDQ TAQEMQEKLQ NFAQLPAHRV TDSCIVALLS HGVEGAIYGV 120
  121 DGKLLQLQEV FQLFDNANCP SLQNKPKMFF IQACRGDETD RGVDQQD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.522879
Match: 1pyoA
Description: Crystal Structure of Human Caspase-2 in Complex with Acetyl-Leu-Asp-Glu-Ser-Asp-cho
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.509020836113671 bayes_pls_golite062009
binding 0.21939605213028 bayes_pls_golite062009
hydrolase activity 0.19112054191813 bayes_pls_golite062009
protein binding 0.08628045338074 bayes_pls_golite062009
peptidase activity 0.06679726457289 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle