YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39654530, gi\|...
Organism:	Escherichia coli
Length:	143 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39654530, gi|....

Description	E-value	Query Range	Subject Range
gi\|39654529, gi\|... - gi\|39654529\|pdb\|1PQF\|B Chain B, Glycine 24 To Serine Mutation Of Aspartate Decarboxylase, gi\|3965452...	235.0	[0..1]	[143..1]
PAND_RHOFT - Aspartate 1-decarboxylase OS=Rhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) GN=pa...	227.0	[0..18]	[143..1]
gi\|134281168, gi... - gi\|134281168\|ref\|ZP_01767877.1\| aspartate 1-decarboxylase [Burkholderia pseudomallei 305], gi\|134247... gi\|167909976 - gi\|167909976\|ref\|ZP_02497067.1\| aspartate alpha-decarboxylase [Burkholderia pseudomallei 112] gi\|167918009 - gi\|167918009\|ref\|ZP_02505100.1\| aspartate alpha-decarboxylase [Burkholderia pseudomallei BCC215] gi\|167844741 - gi\|167844741\|ref\|ZP_02470249.1\| aspartate alpha-decarboxylase [Burkholderia pseudomallei B7210] gi\|167893277 - gi\|167893277\|ref\|ZP_02480679.1\| aspartate alpha-decarboxylase [Burkholderia pseudomallei 7894] gi\|194313199, gi... - gi\|254177536\|ref\|ZP_04884191.1\| aspartate 1-decarboxylase [Burkholderia mallei ATCC 10399], gi\|19431... gi\|217397617, gi... - gi\|217420313\|ref\|ZP_03451819.1\| aspartate 1-decarboxylase [Burkholderia pseudomallei 576], gi\|217397... PAND_BURP1 - Aspartate 1-decarboxylase OS=Burkholderia pseudomallei (strain 1710b) GN=panD PE=3 SV=1 gi\|85067129 - gi\|85067129\|ref\|ZP_01027982.1\| COG0853: Aspartate 1-decarboxylase [Burkholderia mallei 10229] gi\|194574726, gi... - gi\|87315848\|ref\|ZP_01096871.1\| COG0853: Aspartate 1-decarboxylase [Burkholderia mallei 2002721280], ... gi\|238520340, gi... - gi\|67639742\|ref\|ZP_00438578.1\| aspartate 1-decarboxylase [Burkholderia mallei GB8 horse 4], gi\|23852... PAND_BURM7 - Aspartate 1-decarboxylase OS=Burkholderia mallei (strain NCTC 10247) GN=panD PE=3 SV=1 gi\|194570048, gi... - gi\|83680507\|ref\|ZP_00942212.1\| COG0853: Aspartate 1-decarboxylase [Burkholderia pseudomallei 406e], ... gi\|100915638, gi... - gi\|67636222\|ref\|ZP_00435169.1\| COG0853: Aspartate 1-decarboxylase [Burkholderia mallei 10399], gi\|10... gi\|254190812, gi... - gi\|67752095\|ref\|ZP_00491111.1\| COG0853: Aspartate 1-decarboxylase [Burkholderia pseudomallei Pasteur... PAND_BURMS - Aspartate 1-decarboxylase OS=Burkholderia mallei (strain SAVP1) GN=panD PE=3 SV=1 gi\|254181413, gi... - gi\|99910338\|ref\|ZP_01317365.1\| hypothetical protein Bpse1_03003285 [Burkholderia pseudomallei 1655],... gi\|67685361, gi\|... - gi\|90293941\|ref\|ZP_01213538.1\| hypothetical protein Bpse17_02001242 [Burkholderia pseudomallei 1710a... gi\|83619036, gi\|... - gi\|83619036\|ref\|ZP_00929480.1\| COG0853: Aspartate 1-decarboxylase [Burkholderia mallei FMH], gi\|2541... gi\|147753133, gi... - gi\|83623928\|ref\|ZP_00934186.1\| COG0853: Aspartate 1-decarboxylase [Burkholderia mallei JHU], gi\|2542... PAND_BURP0 - Aspartate 1-decarboxylase OS=Burkholderia pseudomallei (strain 1106a) GN=panD PE=1 SV=1 gi\|82536563, gi\|... - gi\|82536563\|ref\|ZP_00895568.1\| hypothetical protein Bpse110_02002225 [Burkholderia pseudomallei 1106... PAND_BURPS - Aspartate 1-decarboxylase OS=Burkholderia pseudomallei (strain K96243) GN=panD PE=3 SV=1 PAND_BURMA - Aspartate 1-decarboxylase OS=Burkholderia mallei (strain ATCC 23344) GN=panD PE=3 SV=1 PAND_BURM9 - Aspartate 1-decarboxylase OS=Burkholderia mallei (strain NCTC 10229) GN=panD PE=3 SV=1 gi\|167737589 - gi\|167737589\|ref\|ZP_02410363.1\| aspartate alpha-decarboxylase [Burkholderia pseudomallei 14] gi\|167814724 - gi\|167814724\|ref\|ZP_02446404.1\| aspartate alpha-decarboxylase [Burkholderia pseudomallei 91] gi\|243061360, gi... - gi\|243061360\|gb\|EES43546.1\| aspartate 1-decarboxylase [Burkholderia mallei PRL-20], gi\|167003058\|ref... gi\|167718562 - gi\|167718562\|ref\|ZP_02401798.1\| aspartate alpha-decarboxylase [Burkholderia pseudomallei DM98] PAND_BURMA - Aspartate 1-decarboxylase OS=Burkholderia mallei GN=panD PE=3 SV=1 PAND_BURPS - Aspartate 1-decarboxylase OS=Burkholderia pseudomallei GN=panD PE=3 SV=1	225.0	[0..18]	[141..1]
gi\|237811312, gi... - gi\|237811312\|ref\|YP_002895763.1\| aspartate 1-decarboxylase [Burkholderia pseudomallei MSHR346], gi\|2... gi\|167901736 - gi\|167901736\|ref\|ZP_02488941.1\| aspartate alpha-decarboxylase [Burkholderia pseudomallei NCTC 13177] PAND_BURP6 - Aspartate 1-decarboxylase OS=Burkholderia pseudomallei (strain 668) GN=panD PE=3 SV=1 gi\|67760582, gi\|... - gi\|67760582\|ref\|ZP_00499302.1\| COG0853: Aspartate 1-decarboxylase [Burkholderia pseudomallei S13], g... gi\|225933561, gi... - gi\|226194476\|ref\|ZP_03790074.1\| aspartate 1-decarboxylase [Burkholderia pseudomallei Pakistan 9], gi...	225.0	[0..18]	[141..1]
PAND_CHRVO - Aspartate 1-decarboxylase OS=Chromobacterium violaceum GN=panD PE=3 SV=1 PAND_CHRVO - Aspartate 1-decarboxylase OS=Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / N...	224.0	[0..18]	[143..1]
PAND_BURTA - Aspartate 1-decarboxylase OS=Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP... gi\|167618272 - gi\|167618272\|ref\|ZP_02386903.1\| aspartate alpha-decarboxylase [Burkholderia thailandensis Bt4] gi\|167580170 - gi\|167580170\|ref\|ZP_02373044.1\| aspartate alpha-decarboxylase [Burkholderia thailandensis TXDOH]	224.0	[0..18]	[141..1]
PAND_POLNA - Aspartate 1-decarboxylase OS=Polaromonas naphthalenivorans (strain CJ2) GN=panD PE=1 SV=1	224.0	[0..18]	[143..1]

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Predicted Domain #1

Region A:
Residues: [1-143]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGSHHHHHH GLVPRGSMIR TMLQGKLHRV KVTHADLHYE GTCAIDQDFL DAAGILENEA  60
   61 IDIWNVTNGK RFSTYAIAAE RGSRIISVNG AAAHXASVGD IVIIASFVTM PDEEARTWRP 120
  121 NVAYFEGDNE MKRTAKAIPV QVA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.69897
Match:	1pqfA
Description:	Glycine 24 to Serine mutation of aspartate decarboxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
aspartate 1-decarboxylase activity	5.28630608185839	bayes_pls_golite062009
carboxy-lyase activity	1.90738294399091	bayes_pls_golite062009
catalytic activity	1.55034677075026	bayes_pls_golite062009
carbon-carbon lyase activity	1.31402947495071	bayes_pls_golite062009
lyase activity	0.300409233756216	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: