YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|168760330, gi...
Organism:	Escherichia coli O157:H7 str. EC4501
Length:	160 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|168760330, gi....

Description	E-value	Query Range	Subject Range
ALLA_ECOUT - Ureidoglycolate lyase OS=Escherichia coli (strain UTI89 / UPEC) GN=allA PE=3 SV=1 ALLA_ECOL5 - Ureidoglycolate lyase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=allA PE=3 SV=1 ALLA_ECOK1 - Ureidoglycolate lyase OS=Escherichia coli O1:K1 / APEC GN=allA PE=3 SV=1 ALLA_ECO81 - Ureidoglycolate lyase OS=Escherichia coli O81 (strain ED1a) GN=allA PE=3 SV=1 ALLA_ECO45 - Ureidoglycolate lyase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=allA PE=3 SV=1 ALLA_ECO27 - Ureidoglycolate lyase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=allA PE=3 SV=1 sp\|B7UKI3\|ALLA_ECO27 - Ureidoglycolate hydrolase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=allA PE=3 SV=1 gi\|190907365, gi... - gi\|75240699\|ref\|ZP_00724606.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli F11], gi\|1911722... ALLA_ECOLU - Ureidoglycolate lyase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=allA PE=3 SV=1	246.0	[0..1]	[160..1]
ALLA_ECOL6 - Ureidoglycolate lyase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=allA PE=3 SV... ALLA_ECOL6 - Ureidoglycolate hydrolase OS=Escherichia coli O6 GN=allA PE=3 SV=1 gi\|227838572, gi... - gi\|227884486\|ref\|ZP_04002291.1\| ureidoglycolate hydrolase [Escherichia coli 83972], gi\|227838572\|gb\|...	245.0	[0..1]	[160..1]
gi\|75257854, gi\|... - gi\|75257854\|ref\|ZP_00729332.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli E22], gi\|1930641... ALLA_ECO8A - Ureidoglycolate lyase OS=Escherichia coli O8 (strain IAI1) GN=allA PE=3 SV=1 gi\|75209190, gi\|... - gi\|75209190\|ref\|ZP_00709441.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli B171], gi\|194429... ALLA_ECO55 - Ureidoglycolate lyase OS=Escherichia coli (strain 55989 / EAEC) GN=allA PE=3 SV=1 ALLA_ECO24 - Ureidoglycolate lyase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=allA PE=3 SV=1	245.0	[0..1]	[160..1]
ALLA_ECODH - Ureidoglycolate lyase OS=Escherichia coli (strain K12 / DH10B) GN=allA PE=1 SV=1 EG13615 - ureidoglycolate lyase, releasing urea / Ureidoglycolate lyase, releasing urea gi\|85674643, gi\|... - gi\|89107373\|ref\|AP_001153.1\| ureidoglycolate hydrolase [Escherichia coli str. K-12 substr. W3110], g... ALLA_ECOBW - Ureidoglycolate lyase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=allA PE=3 SV=1 EG13615 - ureidoglycolate lyase, releasing urea / Ureidoglycolate lyase, releasing urea ALLA_ECOLI - Ureidoglycolate hydrolase (EC 3.5.3.19) - Escherichia coli	243.0	[0..1]	[160..1]
gi\|82407523, gi\|... - gi\|82407524\|pdb\|1YQC\|B Chain B, Crystal Structure Of Ureidoglycolate Hydrolase (Alla) From Escherich...	241.0	[0..2]	[160..2]
gi\|56554717, gi\|... - gi\|56554718\|pdb\|1XSR\|B Chain B, X-Ray Structure Of Northeast Structural Genomics Consortium Target S...	241.0	[0..2]	[160..2]
gi\|238911355 - gi\|238911355\|ref\|ZP_04655192.1\| ureidoglycolate hydrolase [Salmonella enterica subsp. enterica serov... ALLA_SALPB - Ureidoglycolate hydrolase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=allA PE=3 SV=1 ALLA_SALPA - Ureidoglycolate hydrolase OS=Salmonella paratyphi A GN=allA PE=3 SV=1 gi\|199602719, gi... - gi\|200390274\|ref\|ZP_03216885.1\| ureidoglycolate hydrolase [Salmonella enterica subsp. enterica serov... ALLA_SALDC - Ureidoglycolate lyase OS=Salmonella dublin (strain CT_02021853) GN=allA PE=3 SV=1 ALLA_SALPA - Ureidoglycolate lyase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=allA PE=3 SV=1 ALLA_SALPK - Ureidoglycolate lyase OS=Salmonella paratyphi A (strain AKU_12601) GN=allA PE=3 SV=1 gi\|197241067, gi... - gi\|197262812\|ref\|ZP_03162886.1\| ureidoglycolate hydrolase [Salmonella enterica subsp. enterica serov... ALLA_SALA4 - Ureidoglycolate lyase OS=Salmonella agona (strain SL483) GN=allA PE=3 SV=1 gi\|194457876, gi... - gi\|194471512\|ref\|ZP_03077496.1\| ureidoglycolate hydrolase [Salmonella enterica subsp. enterica serov... ALLA_SALHS - Ureidoglycolate lyase OS=Salmonella heidelberg (strain SL476) GN=allA PE=3 SV=1 ALLA_SALNS - Ureidoglycolate lyase OS=Salmonella newport (strain SL254) GN=allA PE=3 SV=1 gi\|205344229, gi... - gi\|205344229\|gb\|EDZ30993.1\| ureidoglycolate hydrolase [Salmonella enterica subsp. enterica serovar W... gi\|195631880, gi... - gi\|195631880\|gb\|EDX50400.1\| ureidoglycolate hydrolase [Salmonella enterica subsp. enterica serovar N... ALLA_SALPB - Ureidoglycolate lyase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=allA PE=3 SV=1 gi\|205349959, gi... - gi\|205349959\|gb\|EDZ36590.1\| ureidoglycolate hydrolase [Salmonella enterica subsp. enterica serovar H... gi\|168240349, gi... - gi\|205340171\|gb\|EDZ26935.1\| ureidoglycolate hydrolase [Salmonella enterica subsp. enterica serovar H... gi\|168231511, gi... - gi\|205333971\|gb\|EDZ20735.1\| ureidoglycolate hydrolase [Salmonella enterica subsp. enterica serovar K... gi\|167550953, gi... - gi\|205324131\|gb\|EDZ11970.1\| ureidoglycolate hydrolase [Salmonella enterica subsp. enterica serovar S...	238.0	[0..1]	[160..1]
ALLA_PSEA7 - Ureidoglycolate lyase OS=Pseudomonas aeruginosa (strain PA7) GN=allA PE=3 SV=1	238.0	[0..3]	[156..4]
ALLA_PSEE4 - Ureidoglycolate lyase OS=Pseudomonas entomophila (strain L48) GN=allA PE=3 SV=1 gi\|95109828 - gi\|95109828\|emb\|CAK14533.1\| Ureidoglycolate hydrolase [Pseudomonas entomophila L48]	238.0	[0..3]	[159..4]

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Predicted Domain #1

Region A:
Residues: [1-160]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLQVLPLSQ EAFSAYGDVI ETQQRDFFHI NNGLVERYHD LALVEILEQD RTLISINRAQ  60
   61 PANLPLTIHE LERHPLGTQA FIPMKGEVFV VVVALGDDKP DLSTLRAFIT NGEQGVNYHR 120
  121 NVWHHPLFAW QRVTDFLTID RGGSDNCDVE SIPEQELCFA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.0
Match:	1yqcA
Description:	Crystal Structure of Ureidoglycolate Hydrolase (AllA) from Escherichia coli O157:H7
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ureidoglycolate hydrolase activity	2.63080015873229	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1.64225826538892	bayes_pls_golite062009
dioxygenase activity	0.930778069601015	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	0.901194069960417	bayes_pls_golite062009
binding	0.797072992275176	bayes_pls_golite062009
nucleic acid binding	0.623892372229422	bayes_pls_golite062009
DNA binding	0.483453407263708	bayes_pls_golite062009
transcription regulator activity	0.465649136635506	bayes_pls_golite062009
catalytic activity	0.401988496917198	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: