YRC Public Data Repository - Protein Structure Prediction

Protein:	RLME_PSEA8
Organism:	Pseudomonas aeruginosa LESB58
Length:	207 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RLME_PSEA8.

Description	E-value	Query Range	Subject Range
gi\|89080519, gi\|... - gi\|89095222\|ref\|ZP_01168145.1\| cell division protein FtsJ [Oceanospirillum sp. MED92], gi\|89080519\|g...	6.0E-53	[1..206]	[1..206]
gi\|107103849 - gi\|107103849\|ref\|ZP_01367767.1\| hypothetical protein PaerPA_01004920 [Pseudomonas aeruginosa PACS2]	9.0E-52	[1..207]	[1..207]
gi\|194555331, gi... - gi\|84323593\|ref\|ZP_00971662.1\| COG0293: 23S rRNA methylase [Pseudomonas aeruginosa 2192], gi\|2542443... gi\|84317369, gi\|... - gi\|84317369\|ref\|ZP_00965817.1\| COG0293: 23S rRNA methylase [Pseudomonas aeruginosa C3719], gi\|254238...	1.0E-51	[1..207]	[1..207]
RLME_PSEA7 - Ribosomal RNA large subunit methyltransferase E OS=Pseudomonas aeruginosa (strain PA7) GN=rlmE PE=3 ...	1.0E-51	[1..207]	[1..207]
RLME_SACD2 - Ribosomal RNA large subunit methyltransferase E OS=Saccharophagus degradans (strain 2-40 / ATCC 4396...	4.0E-51	[1..206]	[1..206]
RLME_VIBF1 - Ribosomal RNA large subunit methyltransferase E OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=r...	4.0E-51	[1..206]	[1..209]
gi\|90580530, gi\|... - gi\|90580530\|ref\|ZP_01236335.1\| 23S rRNA methylase [Vibrio angustum S14], gi\|90438188\|gb\|EAS63374.1\| ... gi\|89072568, gi\|... - gi\|89072568\|ref\|ZP_01159140.1\| 23S rRNA methylase [Photobacterium sp. SKA34], gi\|89051672\|gb\|EAR5712...	4.0E-51	[1..205]	[1..208]
gi\|90326515, gi\|... - gi\|90412478\|ref\|ZP_01220481.1\| 23S rRNA methylase [Photobacterium profundum 3TCK], gi\|90326515\|gb\|EA...	5.0E-51	[1..205]	[1..208]
RLME_LEGPL - Ribosomal RNA large subunit methyltransferase E OS=Legionella pneumophila (strain Lens) GN=rlmE PE=3...	9.0E-51	[1..204]	[1..204]
RLME_LEGPA - Ribosomal RNA large subunit methyltransferase E OS=Legionella pneumophila (strain Paris) GN=rlmE PE=... RLME_LEGPH - Ribosomal RNA large subunit methyltransferase E OS=Legionella pneumophila subsp. pneumophila (strain...	1.0E-50	[1..204]	[1..204]

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Predicted Domain #1

Region A:
Residues: [1-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARSKTSQRW LKEHFDDPYV KMAQRDGYRS RASYKLLEIQ EKDRILRPGM TVVDLGAAPG  60
   61 GWSQVTSRVI GDRGRLIASD ILEMDSIPDV TFIQGDFTED AVFARILEAI GDHPVDLVIS 120
  121 DMAPNMSGVR AADQPRAMYL CELALDLAGR VLRPGGDFLI KIFQGEGFDQ YHKQAREMFD 180
  181 KVQMRKPLSS RDRSREQYLL ARGFRGE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.69897
Match:	1eizA
Description:	RNA methyltransferase FtsJ
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	4.15445027778357	bayes_pls_golite062009
rRNA methyltransferase activity	4.09362182773099	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.07153733729662	bayes_pls_golite062009
N-methyltransferase activity	3.67177992319602	bayes_pls_golite062009
protein methyltransferase activity	3.5512266163483	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.39429041855776	bayes_pls_golite062009
RNA methyltransferase activity	3.07428840534971	bayes_pls_golite062009
histone methyltransferase activity	2.49492581548369	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
protein-arginine N-methyltransferase activity	2.06652984530965	bayes_pls_golite062009
arginine N-methyltransferase activity	2.06652984530965	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	1.83964463328968	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	1.75675289134467	bayes_pls_golite062009
DNA-methyltransferase activity	1.63765148226572	bayes_pls_golite062009
histone-arginine N-methyltransferase activity	1.63076727020333	bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity	1.26493190370687	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
tRNA methyltransferase activity	1.12859857407629	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	1.10713374933008	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	0.720411427168235	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	0.703178429468566	bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity	0.606920378432989	bayes_pls_golite062009
transcription regulator activity	0.316272167949639	bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity	0.299393192819978	bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity	0.299393192819978	bayes_pls_golite062009
DNA binding	0.26945982114479	bayes_pls_golite062009
O-methyltransferase activity	0.250946859465502	bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity	0.234572322347698	bayes_pls_golite062009
nucleic acid binding	0.0339414270453529	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: