YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|195939840
Organism:	Escherichia coli O157:H7 str. EC4024
Length:	141 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|195939840.

Description	E-value	Query Range	Subject Range
gi\|78687389, gi\|... - gi\|78687389\|ref\|ZP_00852139.1\| Zn(II)-responsive transcriptional regulator [Shewanella sp. ANA-3], g...	146.0	[0..1]	[140..1]
gi\|82496832, gi\|... - gi\|82496832\|ref\|ZP_00882395.1\| Zn(II)-responsive transcriptional regulator [Shewanella sp. MR-4], gi...	145.0	[0..1]	[140..1]
gi\|16766701, gi\|... - gi\|16766701\|ref\|NP_462316.1\| zinc-responsive transcriptional regulator [Salmonella typhimurium LT2],... lcl\|NC_016856.1_... - [gene=zntR] [protein=zinc-responsive transcriptional regulator] [protein_id=YP_005239602.1] [locatio... gi\|200387120, gi... - gi\|200387120\|ref\|ZP_03213732.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica sub... gi\|204319837, gi... - gi\|204931409\|ref\|ZP_03222078.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica sub... gi\|197364261, gi... - gi\|197364261\|ref\|YP_002143898.1\| zinc-responsive transcriptional regulator [Salmonella enterica subs... gi\|198242753, gi... - gi\|198242753\|ref\|YP_002217375.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica su... gi\|56129588, gi\|... - gi\|56415331\|ref\|YP_152406.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp. e... gi\|194734612, gi... - gi\|194734612\|ref\|YP_002116355.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica su... gi\|197243718, gi... - gi\|197265463\|ref\|ZP_03165537.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica sub... gi\|194406850, gi... - gi\|194448546\|ref\|YP_002047436.1\| zinc-responsive transcriptional regulator [Salmonella enterica subs... gi\|194469471, gi... - gi\|194469471\|ref\|ZP_03075455.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica sub... gi\|168264707, gi... - gi\|205346872\|gb\|EDZ33503.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica subsp. ... gi\|195628893, gi... - gi\|195628893\|gb\|EDX48303.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica subsp. ... gi\|168239755, gi... - gi\|197287581\|gb\|EDY26973.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica subsp. ... gi\|205336012, gi... - gi\|205336012\|gb\|EDZ22776.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica subsp. ... gi\|205327097, gi... - gi\|205327097\|gb\|EDZ13861.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica subsp. ... gi\|205331612, gi... - gi\|205331612\|gb\|EDZ18376.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica subsp. ... gi\|161365801, gi... - gi\|161616437\|ref\|YP_001590402.1\| zinc-responsive transcriptional regulator [Salmonella enterica subs... gi\|205321452, gi... - gi\|205321452\|gb\|EDZ09291.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica subsp. ...	145.0	[0..1]	[141..1]
gi\|224585207, gi... - gi\|224585207\|ref\|YP_002639006.1\| zinc-responsive transcriptional regulator [Salmonella enterica subs... gi\|197213539, gi... - gi\|197249836\|ref\|YP_002148332.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica su... gi\|194401810, gi... - gi\|194443147\|ref\|YP_002042663.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica su... gi\|205340487, gi... - gi\|205340487\|gb\|EDZ27251.1\| Zn(II)-responsive transcriptional regulator [Salmonella enterica subsp. ... gi\|238913873 - gi\|238913873\|ref\|ZP_04657710.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp... gi\|62181917, gi\|... - gi\|62181917\|ref\|YP_218334.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp. e...	144.0	[0..1]	[141..1]
gi\|78688511, gi\|... - gi\|78688511\|ref\|ZP_00853179.1\| Zn(II)-responsive transcriptional regulator [Shewanella sp. MR-7], gi...	143.0	[0..1]	[140..1]
gi\|78361801, gi\|... - gi\|78366213\|ref\|ZP_00836495.1\| regulatory protein, MerR [Shewanella sp. PV-4], gi\|78361801\|gb\|EAP036...	143.0	[0..1]	[132..1]
HMRR_SINMW - HTH-type transcriptional regulator HmrR OS=Sinorhizobium medicae (strain WSM419) GN=hmrR PE=1 SV=1 HMRR_RHIME - HTH-type transcriptional regulator hmrR - Rhizobium meliloti (Sinorhizobium meliloti)	143.0	[0..2]	[140..1]
gi\|68546216, gi\|... - gi\|68546216\|ref\|ZP_00585764.1\| regulatory protein, MerR [Shewanella amazonensis SB2B], gi\|68516044\|g...	143.0	[0..1]	[131..1]
gi\|24345910, gi\|... - gi\|24372038\|ref\|NP_716080.1\| zinc-responsive transcriptional regulator [Shewanella oneidensis MR-1],... SO0443 - transcriptional regulator MerR family	143.0	[0..1]	[138..1]
gi\|213581871 - gi\|213581871\|ref\|ZP_03363697.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp... gi\|213612400 - gi\|213612400\|ref\|ZP_03370226.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp... gi\|213647326 - gi\|213647326\|ref\|ZP_03377379.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp... gi\|213859739 - gi\|213859739\|ref\|ZP_03385443.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp... gi\|213027595 - gi\|213027595\|ref\|ZP_03342042.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp... gi\|213052880 - gi\|213052880\|ref\|ZP_03345758.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp... gi\|213420112 - gi\|213420112\|ref\|ZP_03353178.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp... gi\|213425779 - gi\|213425779\|ref\|ZP_03358529.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp... gi\|29139996, gi\|... - gi\|29144358\|ref\|NP_807700.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp. e... gi\|213999756 - gi\|213999756\|ref\|ZP_03410491.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp... gi\|16762871 - gi\|16762871\|ref\|NP_458488.1\| zinc-responsive transcriptional regulator [Salmonella enterica subsp. e... gi\|16505178, gi\|... - gi\|25302884\|pir\|\|AE1009 probable Zn(II)-responsive regulator zntR [imported] - Salmonella enterica s...	143.0	[0..1]	[141..1]

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Predicted Domain #1

Region A:
Residues: [1-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYRIGELAKM AEVTPDTIRY YEKQQMMEHE VRTEGGFRLY TESDLQRLKF IRHARQLGFS  60
   61 LESIRELLSI RIDPEHHTCQ ESKGIVQERL QEVEARIAEL QSMQRSLQRL NDACCGTAHS 120
  121 SVYCSILEAL EQGASGVKSG C

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.045757
Match:	1q08A
Description:	Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional regulator, at 1.9 A resolution (space group P212121)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.93045200338189	bayes_pls_golite062009
DNA binding	2.76021735963177	bayes_pls_golite062009
nucleic acid binding	2.74030354422037	bayes_pls_golite062009
transcription factor activity	2.40971210693942	bayes_pls_golite062009
binding	2.02368770517087	bayes_pls_golite062009
transcription activator activity	0.653537232350623	bayes_pls_golite062009
protein binding	0.539362924655427	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: