YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|172084715, gi...
Organism:	Bacillus anthracis str. A0174
Length:	289 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|172084715, gi....

Description	E-value	Query Range	Subject Range
gi\|30020517, gi\|... - gi\|30020517\|ref\|NP_832148.1\| RNA polymerase sigma factor SigJ [Bacillus cereus ATCC 14579], gi\|29896...	9.0E-66	[1..289]	[1..289]
gi\|218903588, gi... - gi\|218903588\|ref\|YP_002451422.1\| RNA polymerase sigma-70 factor, ECF subfamily [Bacillus cereus AH82... gi\|195993616, gi... - gi\|196033936\|ref\|ZP_03101347.1\| RNA polymerase sigma-70 factor, ECF subfamily [Bacillus cereus W], g... gi\|49477707, gi\|... - gi\|49477707\|ref\|YP_036574.1\| RNA polymerase sigma factor SigJ [Bacillus thuringiensis serovar konkuk...	2.0E-65	[1..289]	[1..289]
gi\|47553260, gi\|... - gi\|47570058\|ref\|ZP_00240718.1\| RNA polymerase ECF-type sigma factor [Bacillus cereus G9241], gi\|4755...	4.0E-64	[1..289]	[1..289]
gi\|52143032, gi\|... - gi\|52143032\|ref\|YP_083797.1\| RNA polymerase sigma factor SigJ [Bacillus cereus E33L], gi\|51976501\|gb...	6.0E-64	[1..289]	[1..289]
gi\|163940227, gi... - gi\|89207622\|ref\|ZP_01186159.1\| Sigma-70 region 2 [Bacillus weihenstephanensis KBAB4], gi\|89154441\|gb...	3.0E-61	[1..287]	[1..287]
gi\|25494634 - pir\|\|H83733 RNA polymerase ECF-type sigma factor BH0672 [imported] - Bacillus halodurans (strain C-1... gi\|10173286, gi\|... - gi\|15613235\|ref\|NP_241538.1\| RNA polymerase sigma factor SigJ [Bacillus halodurans C-125], gi\|101732...	3.0E-61	[4..282]	[5..281]
gi\|113900979, gi... - gi\|159897484\|ref\|YP_001543731.1\| ECF subfamily RNA polymerase sigma-24 factor [Herpetosiphon auranti...	8.0E-57	[5..285]	[5..281]
gi\|108805168, gi... - ref\|ZP_00186141.1\| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [...	9.0E-56	[1..285]	[1..281]
gi\|37520238, gi\|... - gi\|37520238\|ref\|NP_923615.1\| RNA polymerase sigma-70 factor [Gloeobacter violaceus PCC 7421], gi\|352...	1.0E-55	[1..289]	[8..294]
gi\|45514616, gi\|... - gi\|73539289\|ref\|YP_299656.1\| RNA polymerase sigma factor SigJ [Ralstonia eutropha JMP134], gi\|721226...	4.0E-54	[2..286]	[8..285]

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Predicted Domain #1

Region A:
Residues: [1-165]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METEQLYEAY QPLLFSLAYR ILGSVMDAED IVQDVFISLN NIENLQSIEN MKAFLCKMAT  60
   61 NRSIDKLRSA AHKRNVYVGM WLPEPLVEES NEPSESFVMK ESLSTAYLLL LQQLSEVERI 120
  121 VFILREVFSY EYEEIASIVD KSSVNCRKIF QRARKSILDK PKQST

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.0
Match:	1or7A
Description:	SigmaE factor (RpoE)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription initiation factor activity	5.71806750193815	bayes_pls_golite062009
sigma factor activity	5.58029806879061	bayes_pls_golite062009
transcription regulator activity	3.67872017549582	bayes_pls_golite062009
binding	1.02634976114785	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [166-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSTKKMAAYV EKFVSSLQCG DAQGMLEVLK TDAILKADGG GKVTTAIHPI YSADRIIRLF  60
   61 FGIAQRLTEA YTVDFKMVNG MPGVIVTINN KITYVLSFAF EDEKISNIYM VGNPEKLMHL 120
  121 NVKI

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.48
Match:	2bngA
Description:	Structure of an M.tuberculosis LEH-like epoxide hydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.65597262896834	bayes_pls_golite062009
protein binding	0.745218557375967	bayes_pls_golite062009
nucleic acid binding	0.492648936240102	bayes_pls_golite062009
catalytic activity	0.153463201473105	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: