YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|37927289
Organism:	Homo sapiens
Length:	232 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|37927289.

Description	E-value	Query Range	Subject Range
gi\|114627460 - gi\|114627460\|ref\|XP_520345.2\| PREDICTED: hypothetical protein [Pan troglodytes]	226.0	[0..2]	[231..360]
gi\|94366203 - gi\|94366203\|ref\|XP_995211.1\| PREDICTED: similar to Retinoic acid receptor RXR-alpha (Retinoid X rece...	225.0	[0..2]	[231..228]
gi\|68396885 - gi\|68396885\|ref\|XP_683221.1\| PREDICTED: similar to retinoid X receptor-alpha [Danio rerio]	223.0	[0..2]	[231..294]
gi\|148747360, gi... - gi\|149039209\|gb\|EDL93429.1\| retinoid X receptor alpha, isoform CRA_a [Rattus norvegicus], gi\|1487473...	222.0	[0..2]	[231..226]
gi\|83026436 - gi\|83026436\|gb\|ABB96254.1\| retinoid X receptor, alpha [Homo sapiens]	222.0	[0..2]	[231..211]

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Predicted Domain #1

Region A:
Residues: [1-232]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHGELTPDQQ TLLHFIMDSY NKQRMPQEIT NKILKEEFSA EENFLILTEM ATNHVQVLVE  60
   61 FTKKLPGFQT LDHEDQIALL KGSAVEAMFL RSAEIFNKKL PSGHSDLLEE RIRNSGISDE 120
  121 YITPMFSFYK SIGELKMTQE EYALLTAIVI LSPDRQYIKD REAVEKLQEP LLDVLQKLCK 180
  181 IHQPENPQHF ACLLGRLTEL RTFNHHHAEM LMSWRVNDHK FTPLLCEIWD VQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.69897
Match:	1oshA
Description:	A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.15996699473685	bayes_pls_golite062009
transcription regulator activity	0.46162010671465	bayes_pls_golite062009
protein binding	0.33427459029264	bayes_pls_golite062009
nucleic acid binding	0.15459949087509	bayes_pls_golite062009
DNA binding	0.14395376162921	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: