YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|167056375, gi...
Organism:	Yersinia pestis biovar Mediaevalis str. K1973002
Length:	190 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|167056375, gi....

Description	E-value	Query Range	Subject Range
gi\|21958397, gi\|... - gi\|22125501\|ref\|NP_668924.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis KIM], gi\|... gi\|162421715, gi... - gi\|162421715\|ref\|YP_001604962.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis Angol... gi\|45442180, gi\|... - gi\|45442180\|ref\|NP_993719.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Yersinia pestis biovar Mi...	2.0E-63	[1..190]	[6..195]
gi\|49612500, gi\|... - gi\|50121974\|ref\|YP_051141.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Pectobacterium atroseptic...	3.0E-62	[1..188]	[1..188]
gi\|37527052, gi\|... - gi\|37527052\|ref\|NP_930396.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Photorhabdus luminescens ...	3.0E-62	[1..188]	[1..188]
gi\|75177900, gi\|... - gi\|75177900\|ref\|ZP_00697962.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Shigella boydi... gi\|191169483, gi... - gi\|75227193\|ref\|ZP_00713997.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|73856305, gi\|... - gi\|74312828\|ref\|YP_311247.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Shigella sonnei Ss046], g... gi\|81246203, gi\|... - gi\|82544792\|ref\|YP_408739.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Shigella boydii Sb227], g... gi\|218554866, gi... - gi\|218554866\|ref\|YP_002387779.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli IAI1...	8.0E-62	[1..188]	[1..188]
EG11044 - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase / 3-octaprenyl-4-hydroxybenzoate carboxylyase; UbiD iso... gi\|238859826, gi... - gi\|238901486\|ref\|YP_002927282.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli BW29... gi\|242377944, gi... - gi\|251785671\|ref\|YP_002999975.1\| hypothetical protein B21_02196 [Escherichia coli BL21], gi\|24237794... gi\|253323809, gi... - gi\|254289081\|ref\|YP_003054829.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli BL21... gi\|253974221, gi... - gi\|254162320\|ref\|YP_003045428.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli B st... gi\|157157444, gi... - gi\|75187093\|ref\|ZP_00700360.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|254794204, gi... - gi\|254794204\|ref\|YP_003079041.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157... gi\|157161799, gi... - gi\|75196354\|ref\|ZP_00706424.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|75209298, gi\|... - gi\|75209298\|ref\|ZP_00709538.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|75238094, gi\|... - gi\|75238094\|ref\|ZP_00722099.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|192931898, gi... - gi\|75259770\|ref\|ZP_00731072.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|75515676, gi\|... - gi\|75515676\|ref\|ZP_00737811.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|81241870, gi\|... - gi\|82777722\|ref\|YP_404071.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Shigella dysenteriae Sd19... gi\|170683430, gi... - gi\|170683430\|ref\|YP_001744511.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli SMS-... gi\|169889762, gi... - gi\|170081927\|ref\|YP_001731247.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli str.... gi\|208729363, gi... - gi\|208809562\|ref\|ZP_03251899.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:... gi\|195935690 - gi\|195935690\|ref\|ZP_03081072.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:... gi\|208821293, gi... - gi\|208821293\|ref\|ZP_03261613.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:... gi\|208733641, gi... - gi\|208812364\|ref\|ZP_03253693.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:... gi\|209919811, gi... - gi\|209919811\|ref\|YP_002293895.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli SE11... gi\|194436312, gi... - gi\|83588294\|ref\|ZP_00926919.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|209158865, gi... - gi\|209397465\|ref\|YP_002271720.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157... UBIX_ECOLI - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase (EC 4.1.1.-) (Polyprenyl p-hydroxybenzoate decarboxylas... gi\|189357664, gi... - gi\|189357664\|gb\|EDU76083.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:H7 s... gi\|188017317, gi... - gi\|188017317\|gb\|EDU55439.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:H7 s... gi\|189362974, gi... - gi\|189362974\|gb\|EDU81393.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:H7 s... gi\|189368295, gi... - gi\|189368295\|gb\|EDU86711.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:H7 s... gi\|168780170, gi... - gi\|189001904\|gb\|EDU70890.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:H7 s... gi\|187771283, gi... - gi\|187771283\|gb\|EDU35127.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:H7 s... gi\|189379033, gi... - gi\|189379033\|gb\|EDU97449.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:H7 s... gi\|189372847, gi... - gi\|189372847\|gb\|EDU91263.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:H7 s... gi\|218352642, gi... - gi\|218695910\|ref\|YP_002403577.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli 5598... gi\|217326945, gi... - gi\|217326945\|ref\|ZP_03443028.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:... gi\|195183050 - gi\|195183050\|dbj\|BAG66610.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O111:H-] gi\|218370773, gi... - gi\|218700787\|ref\|YP_002408416.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli IAI3... EG11044 - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase / 3-octaprenyl-4-hydroxybenzoate carboxylyase; UbiD iso... UBIX_ECO57 - Flavin prenyltransferase UbiX OS=Escherichia coli O157:H7 GN=ubiX PE=3 SV=1 gi\|12516670, gi\|... - gi\|15802858\|ref\|NP_288885.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:H7 ... gi\|1799692, gi\|8... - gi\|89109131\|ref\|AP_002911.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli str. K-1... gi\|15832449, gi\|... - gi\|15832449\|ref\|NP_311222.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:H7 ...	2.0E-61	[1..188]	[1..188]
gi\|238723276, gi... - gi\|77975504\|ref\|ZP_00831039.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Yersinia frede...	2.0E-61	[1..190]	[1..190]
gi\|77960841, gi\|... - gi\|77960841\|ref\|ZP_00824696.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Yersinia molla...	2.0E-61	[1..190]	[1..190]
gi\|226901155, gi... - gi\|237704789\|ref\|ZP_04535270.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia sp. 3_2_53... gi\|117624501, gi... - gi\|117624501\|ref\|YP_853414.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli APEC O1... gi\|91211607, gi\|... - gi\|91211607\|ref\|YP_541593.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli UTI89], ... gi\|110344107, gi... - gi\|110642515\|ref\|YP_670245.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli 536], g... gi\|215265596, gi... - gi\|215487524\|ref\|YP_002329955.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O127... gi\|75243122, gi\|... - gi\|75243122\|ref\|ZP_00726828.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Escherichia co... gi\|218365993, gi... - gi\|218559224\|ref\|YP_002392137.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli S88]... gi\|218428035, gi... - gi\|218690471\|ref\|YP_002398683.1\| 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli ED1a...	3.0E-61	[1..188]	[1..188]
gi\|238785199, gi... - gi\|77957375\|ref\|ZP_00821433.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Yersinia berco...	3.0E-61	[1..190]	[1..190]
gi\|238795095, gi... - gi\|77976974\|ref\|ZP_00832437.1\| COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase [Yersinia inter...	4.0E-61	[1..190]	[1..190]

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Predicted Domain #1

Region A:
Residues: [1-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRLIIGISG ASGAIYGVRL LQVLQHVEGV ETHLIISNAA RQTLALETDY SVKDVQEFAD  60
   61 VVHDFRDIAA CISSGSFKTD GMVILPCSIK TLSGIVHSYT DGLLTRAADV ILKERRRLVL 120
  121 CVRETPLHLG HLRLMVQAAE LGAVIMPPML AFYHQPQTIQ DIIDQTVNRI IDQFDIELPK 180
  181 DLFTRWQGKN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.154902
Match:	1sbzA
Description:	Crystal Structure of dodecameric FMN-dependent Ubix-like Decarboxylase from Escherichia coli O157:H7
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	5.88631349530005	bayes_pls_golite062009
carboxy-lyase activity	2.27469953971238	bayes_pls_golite062009
catalytic activity	1.88716391063227	bayes_pls_golite062009
carbon-carbon lyase activity	1.67751595868044	bayes_pls_golite062009
phosphopantothenoylcysteine decarboxylase activity	1.6488492075417	bayes_pls_golite062009
lyase activity	0.646446561158526	bayes_pls_golite062009
phosphopantothenate--cysteine ligase activity	0.35505046579356	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: