YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|215410186
Organism:	Mycobacterium tuberculosis 94_M4241A
Length:	238 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|215410186.

Description	E-value	Query Range	Subject Range
gi\|254776958 - gi\|254776958\|ref\|ZP_05218474.1\| transcription antitermination protein NusG [Mycobacterium avium subs... gi\|41410209, gi\|... - gi\|41410209\|ref\|NP_963045.1\| transcription antitermination protein NusG [Mycobacterium avium subsp. ... gi\|118167394, gi... - gi\|118466107\|ref\|YP_883656.1\| transcription antitermination protein NusG [Mycobacterium avium 104], ...	252.0	[0..1]	[238..1]
gi\|221230497, gi... - gi\|221230497\|ref\|YP_002503913.1\| transcription antitermination protein nusG [Mycobacterium leprae Br... NUSG_MYCLE - Transcription antitermination protein nusG OS=Mycobacterium leprae GN=nusG PE=3 SV=1 NUSG_MYCLE - Transcription termination/antitermination protein NusG OS=Mycobacterium leprae (strain TN) GN=nusG P...	249.0	[0..17]	[238..7]
gi\|89338459, gi\|... - gi\|89338459\|ref\|ZP_01191224.1\| transcription antitermination protein NusG:KOW [Mycobacterium flavesc...	239.0	[0..5]	[238..34]
gi\|110818507, gi... - gi\|111018977\|ref\|YP_701949.1\| transcription antitermination protein NusG [Rhodococcus jostii RHA1], ...	235.0	[0..5]	[238..31]
gi\|92913607, gi\|... - gi\|92913607\|ref\|ZP_01282235.1\| transcription antitermination protein NusG:KOW [Mycobacterium sp. KMS... gi\|108797896, gi... - gi\|108797896\|ref\|YP_638093.1\| transcription antitermination protein NusG [Mycobacterium sp. MCS], gi...	230.0	[0..3]	[238..33]
gi\|54027090, gi\|... - gi\|54027090\|ref\|YP_121332.1\| transcription antitermination protein NusG [Nocardia farcinica IFM 1015...	230.0	[0..4]	[238..38]
gi\|69284922, gi\|... - gi\|69284922\|ref\|ZP_00616621.1\| transcription antitermination protein NusG [Kineococcus radiotolerans...	229.0	[0..3]	[238..243]
gi\|48835068 - ref\|ZP_00292070.1\| COG0250: Transcription antiterminator [Thermobifida fusca] gi\|72163058, gi\|... - gi\|72163058\|ref\|YP_290715.1\| transcription antitermination protein NusG [Thermobifida fusca YX], gi\|...	227.0	[0..20]	[238..43]
gi\|90202745, gi\|... - gi\|90202745\|ref\|ZP_01205391.1\| transcription antitermination protein NusG:KOW [Mycobacterium vanbaal...	227.0	[0..4]	[238..30]
gi\|98660440 - gi\|98660440\|dbj\|GAA02282.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	226.0	[0..45]	[238..4]

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Predicted Domain #1

Region A:
Residues: [1-103]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTFDGDTSA GEAVDLTEAN AFQDAAAPAE EVDPAAALKA ELRSKPGDWY VVHSYAGYEN  60
   61 KVKANLETRV QNLDVGDYIF QVEVPTEEVT EIKNGQRKQV NRK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.41
Match:	1m1gA
Description:	N-utilization substance G protein NusG, insert domain; N-utilization substance G protein NusG, C-terminal domain; N-utilization substance G protein NusG, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [104-238]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLPGYILVRM DLTDDSWAAV RNTPGVTGFV GATSRPSALA LDDVVKFLLP RGSTRKAAKG  60
   61 AASTAAAAEA GGLERPVVEV DYEVGESVTV MDGPFATLPA TISEVNAEQQ KLKVLVSIFG 120
  121 RETPVELTFG QVSKI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.0
Match:	1m1gA
Description:	N-utilization substance G protein NusG, insert domain; N-utilization substance G protein NusG, C-terminal domain; N-utilization substance G protein NusG, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription termination factor activity	7.3828495299519	bayes_pls_golite062009
transcription regulator activity	3.63525538465601	bayes_pls_golite062009
structural constituent of ribosome	2.40236111142017	bayes_pls_golite062009
structural molecule activity	2.11748533169546	bayes_pls_golite062009
nucleic acid binding	0.761013355804059	bayes_pls_golite062009
binding	0.302568764609847	bayes_pls_golite062009
DNA binding	0.302556727687398	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: