YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|31615339, gi\|...
Organism:	Escherichia coli
Length:	297 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|31615339, gi|....

Description	E-value	Query Range	Subject Range
DAPA_BARBK - 4-hydroxy-tetrahydrodipicolinate synthase OS=Bartonella bacilliformis (strain ATCC 35685 / KC583) GN...	360.0	[0..5]	[293..2]
gi\|74420990, gi\|... - gi\|75676120\|ref\|YP_318541.1\| dihydrodipicolinate synthase [Nitrobacter winogradskyi Nb-255], gi\|7442...	350.0	[0..3]	[293..5]
gi\|241906440, gi... - gi\|241906440\|ref\|ZP_04791022.1\| dihydrodipicolinate synthase [Desulfovibrio vulgaris RCH1], gi\|24188... DAPA_DESVV - 4-hydroxy-tetrahydrodipicolinate synthase OS=Desulfovibrio vulgaris subsp. vulgaris (strain DP4) GN=... DAPA_DESVH - 4-hydroxy-tetrahydrodipicolinate synthase OS=Desulfovibrio vulgaris (strain Hildenborough / ATCC 295...	350.0	[0..5]	[293..3]
DAPA_GEOUR - 4-hydroxy-tetrahydrodipicolinate synthase OS=Geobacter uraniireducens (strain Rf4) GN=dapA PE=3 SV=1	349.0	[0..5]	[293..2]
gi\|89360868, gi\|... - gi\|89360868\|ref\|ZP_01198685.1\| Dihydrodipicolinate synthase subfamily [Xanthobacter autotrophicus Py...	348.0	[0..2]	[293..101]
gi\|77388880, gi\|... - gi\|77464462\|ref\|YP_353966.1\| dihydrodipicolinate synthase [Rhodobacter sphaeroides 2.4.1], gi\|773888...	347.0	[0..1]	[293..3]
gi\|91789030, gi\|... - gi\|91789030\|ref\|YP_549982.1\| dihydrodipicolinate synthase [Polaromonas sp. JS666], gi\|91698255\|gb\|AB...	346.0	[0..2]	[293..30]
DAPA_METJA - Dihydrodipicolinate synthase OS=Methanocaldococcus jannaschii GN=dapA PE=1 SV=1 DAPA_METJA - 4-hydroxy-tetrahydrodipicolinate synthase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM ...	345.0	[0..5]	[293..2]
gi\|120610024, gi... - gi\|120610024\|ref\|YP_969702.1\| dihydrodipicolinate synthase [Acidovorax avenae subsp. citrulli AAC00-...	345.0	[0..2]	[293..5]
DAPA_ACIET - 4-hydroxy-tetrahydrodipicolinate synthase OS=Acidovorax ebreus (strain TPSY) GN=dapA PE=3 SV=1 DAPA_ACISJ - 4-hydroxy-tetrahydrodipicolinate synthase OS=Acidovorax sp. (strain JS42) GN=dapA PE=3 SV=1	345.0	[0..2]	[293..5]

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Predicted Domain #1

Region A:
Residues: [1-297]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATNLRGVMA ALLTPFDQQQ ALDKASLRRL VQFNIQQGID GLYVGGSTGE AFVQSLSERE  60
   61 QVLEIVAEEA KGKIKLIAHV GCVSTAESQQ LAASAKRYGF DAVSAVTPFY YPFSFEEHCD 120
  121 HYRAIIDSAD GLPMVVYNIP ARSGVKLTLD QINTLVTLPG VGALKQTSGD LYQMEQIRRE 180
  181 HPDLVLYNGY DEIFASGLLA GADGGIGSTY NIMGWRYQGI VKALKEGDIQ TAQKLQTECN 240
  241 KVIDLLIKTG VFRGLKTVLH YMDVVSVPLC RKPFGPVDEK YLPELKALAQ QLMQERG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	81.221849
Match:	1hl2A
Description:	N-acetylneuraminate lyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.67031204377352	bayes_pls_golite062009
3-deoxy-7-phosphoheptulonate synthase activity	2.02591266233154	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	1.72893315846141	bayes_pls_golite062009
transaldolase activity	1.38790063456575	bayes_pls_golite062009
fructose-bisphosphate aldolase activity	1.13448902636244	bayes_pls_golite062009
lyase activity	0.740424046054758	bayes_pls_golite062009
aldehyde-lyase activity	0.351872954170322	bayes_pls_golite062009
binding	0.038419829456847	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: