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View Structure Prediction Details

Protein: NAGS2_ARATH
Organism: Arabidopsis thaliana
Length: 613 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAGS2_ARATH.

Description E-value Query
Range
Subject
Range
NAGS1_ARATH - Probable amino-acid acetyltransferase NAGS1, chloroplastic OS=Arabidopsis thaliana GN=NAGS1 PE=2 SV=...
401.0 [0..2] [612..3]

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Predicted Domain #1
Region A:
Residues: [1-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERGALVGSS STSSYYVPYH FRQSKSNFSS FKPKNKLNPT QFRFNCSWFK PVSSITAAKC  60
   61 NMFDYAVTAA GDVEAEHPVD DKQFVRWFRE AWPYLWAHRG CTFVVIISGE IIAGSSCDAI 120
  121 LKDIAFLHHL GIRFVLVPGT QEQIDQLLAE RGREATYVGR YRVTDAASLQ AAKEAAGAIS 180
  181 VMLEAKLSPG PSICNIRRHG DRSRLHDIGV RVDTGNFFAA KRRGVVDGVD FGATGEVKKI 240
  241 DVDRICERLD GGSVVLLRNL GHSSSGEVLN CNTYEVATAC ALAIGADKLI CIMDGPILDE 300
  301 SGHLIHF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.522879
Match: 2btyA
Description: Acetylglutamate kinase from Thermotoga maritima complexed with its inhibitor arginine
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
acetylglutamate kinase activity 3.62493177730942 bayes_pls_golite062009
phosphotransferase activity, carboxyl group as acceptor 3.23203925555954 bayes_pls_golite062009
catalytic activity 3.20382750184555 bayes_pls_golite062009
amino acid kinase activity 2.69040298093296 bayes_pls_golite062009
transferase activity 2.54481238004476 bayes_pls_golite062009
glutamate 5-kinase activity 2.08203900247141 bayes_pls_golite062009
aspartate kinase activity 2.03700691370413 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.89315414622708 bayes_pls_golite062009
kinase activity 1.84529070582231 bayes_pls_golite062009
acetyl-CoA:L-glutamate N-acetyltransferase activity 1.28280910531626 bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity 0.72506602549224 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [308-613]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTLQEADMLV RKRAQQSDIA ANYVKAVGDG SMAYPEPPNN TNGNITSAQN GRAVSFWGNG  60
   61 NHTPIFQNGV GFDNGNGLWP CEQGFAIGGE ERLSRLNGYL SELAAAAFVC RGGVKRVHLL 120
  121 DGTISGVLLL ELFKRDGMGT MVASDVYEGT RDARVEDLAG IRHIIKPLEE SGILVRRTDE 180
  181 ELLRALDSFV VVEREGQIIA CAALFPFFKD KCGEVAAIAV ASDCRGQGQG DKLLDYIEKK 240
  241 ASSLGLEKLF LLTTRTADWF VRRGFQECSI EIIPESRRQR INLSRNSKYY MKKLIPDRSG 300
  301 ISVMRI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.69897
Match: 2c27A
Description: The structure of Mycothiol Synthase in complex with des- AcetylMycothiol and CoenzymeA.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
N-acyltransferase activity 3.86250210827155 bayes_pls_golite062009
N-acetyltransferase activity 3.63407851380637 bayes_pls_golite062009
transferase activity, transferring acyl groups 2.81274397387444 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 2.76197390450126 bayes_pls_golite062009
acyltransferase activity 2.70847810129258 bayes_pls_golite062009
catalytic activity 2.34977492703662 bayes_pls_golite062009
transferase activity 1.92514630957121 bayes_pls_golite062009
acetyltransferase activity 1.84361284541304 bayes_pls_golite062009
arginine N-succinyltransferase activity 1.09794747911669 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle