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View Structure Prediction Details

Protein: MED8_ARATH
Organism: Arabidopsis thaliana
Length: 524 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED8_ARATH.

Description E-value Query
Range
Subject
Range
gi|3461831, gi|2... - gi|3461831|gb|AAC32925.1| unknown protein [Arabidopsis thaliana], pir||A84444 hypothetical protein A...
482.0 [0..1] [524..1]
gi|30089732, gi|... - gi|50916695|ref|XP_468744.1| unknown protein [Oryza sativa (japonica cultivar-group)], gi|30089732|g...
395.0 [0..12] [515..25]
NCOA6_MOUSE - Nuclear receptor coactivator 6 OS=Mus musculus GN=Ncoa6 PE=1 SV=1
160.0 [0..259] [520..442]
gi|73975295 - gi|73975295|ref|XP_532376.2| PREDICTED: similar to clock [Canis familiaris]
159.0 [0..269] [513..433]
gi|109471142, gi... - gi|62646123|ref|XP_342553.2| PREDICTED: nuclear receptor coactivator 6 [Rattus norvegicus], gi|14903...
157.0 [0..259] [520..434]
gi|6478192 - gi|6478192|gb|AAF13733.1| clock [Homo sapiens]
156.0 [0..227] [513..395]

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Predicted Domain #1
Region A:
Residues: [1-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METQPQQPPP PPVAEKLNPK LEKELNLESL KTRAVSLAKA IARILEDFDA YGRTNTTPKW  60
   61 QDILGQYSMV NLELFNIVEE VKRVSNAFVV LPKNVNAMNA AILPVMLSSK LLPEMETDDN 120
  121 AKREQLLQGV QSLPIPMQIE RLKARMDMIA AACENAERVL ADTRKAY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [168-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFGTRQGPSM LPTMDKGQAA KIQEQEKMLR DAVNDGKGTQ LPPDQRQITT ALPPHLADVL  60
   61 IINDAGKIAL PGQSNNINNQ GMMQVSGTQF VGRSAASPSG PNFDNTTSPL PYSNSPRATG 120
  121 MVNVPSPQHQ IQQQQFQQQQ QRSKLMQL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [316-524]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQHQQQQLLA QQQQQLRQSS MQGLGQSQIP ALHDMHGQAQ QKFQTSHGQH QMPYSQPMGA  60
   61 HQQFQARQLS GGHIQHSMSQ GQLNPAMNRH LNQFSGGANS ALFTSAQGSP SSQMIPNMSS 120
  121 MQSQTLVPRM QQFGVSGTNP QRSHSSQMLG DQMFNTSGMM QTQQTQIQQS QQQQQQQQQG 180
  181 GYGNMQTNQQ SLQPNNMMQN AQQRHQNPQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.39794
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle