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View Structure Prediction Details

Protein: MED8_ARATH
Organism: Arabidopsis thaliana
Length: 524 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED8_ARATH.

Description E-value Query
Range
Subject
Range
gi|3461831, gi|2... - gi|3461831|gb|AAC32925.1| unknown protein [Arabidopsis thaliana], pir||A84444 hypothetical protein A...
482.0 [0..1] [524..1]
gi|30089732, gi|... - gi|50916695|ref|XP_468744.1| unknown protein [Oryza sativa (japonica cultivar-group)], gi|30089732|g...
395.0 [0..12] [515..25]
NCOA6_MOUSE - Nuclear receptor coactivator 6 OS=Mus musculus GN=Ncoa6 PE=1 SV=1
160.0 [0..259] [520..442]
gi|73975295 - gi|73975295|ref|XP_532376.2| PREDICTED: similar to clock [Canis familiaris]
159.0 [0..269] [513..433]
gi|109471142, gi... - gi|62646123|ref|XP_342553.2| PREDICTED: nuclear receptor coactivator 6 [Rattus norvegicus], gi|14903...
157.0 [0..259] [520..434]
gi|6478192 - gi|6478192|gb|AAF13733.1| clock [Homo sapiens]
156.0 [0..227] [513..395]

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Predicted Domain #1
Region A:
Residues: [1-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METQPQQPPP PPVAEKLNPK LEKELNLESL KTRAVSLAKA IARILEDFDA YGRTNTTPKW  60
   61 QDILGQYSMV NLELFNIVEE VKRVSNAFVV LPKNVNAMNA AILPVMLSSK LLPEMETDDN 120
  121 AKREQLLQGV QSLPIPMQIE RLKARMDMIA AACENAERVL ADTRKAY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [168-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFGTRQGPSM LPTMDKGQAA KIQEQEKMLR DAVNDGKGTQ LPPDQRQITT ALPPHLADVL  60
   61 IINDAGKIAL PGQSNNINNQ GMMQVSGTQF VGRSAASPSG PNFDNTTSPL PYSNSPRATG 120
  121 MVNVPSPQHQ IQQQQFQQQQ QRSKLMQL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.277 a.118.8 TPR-like
View Download 0.219 c.10.1 RNI-like
View Download 0.206 c.14.1 ClpP/crotonase
View Download 0.202 a.25.1 Ferritin-like
View Download 0.202 a.25.1 Ferritin-like

Predicted Domain #3
Region A:
Residues: [316-524]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQHQQQQLLA QQQQQLRQSS MQGLGQSQIP ALHDMHGQAQ QKFQTSHGQH QMPYSQPMGA  60
   61 HQQFQARQLS GGHIQHSMSQ GQLNPAMNRH LNQFSGGANS ALFTSAQGSP SSQMIPNMSS 120
  121 MQSQTLVPRM QQFGVSGTNP QRSHSSQMLG DQMFNTSGMM QTQQTQIQQS QQQQQQQQQG 180
  181 GYGNMQTNQQ SLQPNNMMQN AQQRHQNPQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.39794
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle