YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|23200331, gi\|...
Organism:	Homo sapiens
Length:	123 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|23200331, gi|....

Description	E-value	Query Range	Subject Range
gi\|76676926 - gi\|76676926\|ref\|XP_582666.2\| PREDICTED: similar to Group IIE secretory phospholipase A2 precursor (P...	167.0	[0..2]	[122..314]
gi\|109475713 - gi\|109475713\|ref\|XP_238421.4\| PREDICTED: similar to Group IIE secretory phospholipase A2 precursor (...	148.0	[0..2]	[122..66]
gi\|50805870 - gi\|50805870\|ref\|XP_424364.1\| PREDICTED: similar to group IIE secreted phospholipase A2 [Gallus gallu...	148.0	[0..4]	[122..353]
PLA2G2E - phospholipase A2, group IIE HGNC:13414\|Ensem... - A2, group IIE gi\|147897691, gi... - gi\|208967034\|dbj\|BAG73531.1\| phospholipase A2, group IIE [synthetic construct], gi\|147897691\|gb\|AAI4...	142.0	[0..2]	[122..21]
PA2A8_DABPA - Acidic phospholipase A2 VP8 OS=Daboia palaestinae PE=3 SV=1 PA28_VIPPA - Phospholipase A2 homolog VP8 OS=Vipera palaestinae PE=3 SV=1	142.0	[0..2]	[122..18]
gi\|73950675 - gi\|73950675\|ref\|XP_544525.2\| PREDICTED: similar to Group IIE secretory phospholipase A2 precursor (P...	142.0	[0..2]	[122..46]
PA2A1_NAJAT - Acidic phospholipase A2 1 OS=Naja atra PE=1 SV=2 gi\|395192 - gi\|395192\|emb\|CAA51694.1\| phospholipase a2 [Naja naja]	142.0	[0..2]	[116..29]
PA2A2_NAJKA - Acidic phospholipase A2 2 OS=Naja kaouthia PE=1 SV=3	142.0	[0..2]	[116..29]
gi\|108998698 - gi\|108998698\|ref\|XP_001094364.1\| PREDICTED: phospholipase A2, group IIE [Macaca mulatta]	142.0	[0..2]	[122..21]
PA2BB_GLOHA - Basic phospholipase A2 B OS=Gloydius halys PE=1 SV=2	141.0	[0..2]	[122..18]

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Predicted Domain #1

Region A:
Residues: [1-123]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GILELAGTVG CVGPRTPIAY MKYGCFCGLG GHGQPRDAID WCCHGHDCCY TRAEEAGCSP  60
   61 KTERYSWQCV NQSVLCGPAE NKCQELLCKC DQEIANCLAQ TEYNLKYLFY PQFLCEPDSP 120
  121 KCD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.69897
Match:	1le6A
Description:	Phospholipase A2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phospholipase A2 activity	5.6430968678228	bayes_pls_golite062009
phospholipase activity	5.38445724291842	bayes_pls_golite062009
calcium-dependent phospholipase A2 activity	4.05813159633475	bayes_pls_golite062009
lipase activity	3.51338748073942	bayes_pls_golite062009
cell surface binding	3.03976629465117	bayes_pls_golite062009
carboxylesterase activity	2.68079964970429	bayes_pls_golite062009
receptor binding	1.32351152560027	bayes_pls_golite062009
hydrolase activity	1.24141608423104	bayes_pls_golite062009
binding	1.15315159392399	bayes_pls_golite062009
catalytic activity	0.975181414554529	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.374809125250581	bayes_pls_golite062009
protein binding	0.171634638897769	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: