YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|18655917
Organism:	Homo sapiens
Length:	131 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|18655917.

Description	E-value	Query Range	Subject Range
CENPB_MOUSE - Major centromere autoantigen B OS=Mus musculus GN=Cenpb PE=2 SV=2	156.0	[0..1]	[130..1]
gi\|109470842, gi... - gi\|34858726\|ref\|XP_342522.1\| PREDICTED: similar to Major centromere autoantigen B (Centromere protei...	155.0	[0..1]	[130..1]
CENPB - centromere protein B, 80kDa gi\|208968305 - gi\|208968305\|dbj\|BAG73991.1\| centromere protein B, 80kDa [synthetic construct]	155.0	[0..1]	[130..1]
CENPB_CRIGR - Major centromere autoantigen B OS=Cricetulus griseus GN=CENPB PE=3 SV=1	153.0	[0..1]	[130..1]
gi\|73991901 - gi\|73991901\|ref\|XP_851406.1\| PREDICTED: similar to Major centromere autoantigen B (Centromere protei...	150.0	[0..1]	[130..1]

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Predicted Domain #1

Region A:
Residues: [1-131]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPKRRQLTF REKSRIIQEV EENPDLRKGE IARRFNIPPS TLSTILKNKR AILASERKYG  60
   61 VASTCRKTNK LSPYDKLEGL LIAWFQQIRA AGLPVKGIIL KEKALRIAEE LGMDDFTASN 120
  121 GWLDRFRRRR S

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.09691
Match:	1hlvA
Description:	DNA-binding domain of centromere binding protein B (CENP-B)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.334577365229545	bayes_pls_golite062009
transcription regulator activity	0.0696342306231097	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: