YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|16975162, gi\|...
Organism:	Homo sapiens
Length:	161 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16975162, gi|....

Description	E-value	Query Range	Subject Range
gi\|84512778, gi\|... - gi\|84518029\|ref\|ZP_01005378.1\| thioredoxin peroxidase [Prochlorococcus marinus str. MIT 9211], gi\|84...	154.0	[0..3]	[160..6]
gi\|33865747, gi\|... - gi\|33865747\|ref\|NP_897306.1\| thioredoxin peroxidase [Synechococcus sp. WH 8102], gi\|33632917\|emb\|CAE...	153.0	[0..3]	[160..7]
gi\|51892064, gi\|... - gi\|51892064\|ref\|YP_074755.1\| 2-cys peroxiredoxin [Symbiobacterium thermophilum IAM 14863], gi\|518557...	153.0	[0..5]	[161..4]
gi\|78184723, gi\|... - gi\|78184723\|ref\|YP_377158.1\| thioredoxin peroxidase [Synechococcus sp. CC9902], gi\|78169017\|gb\|ABB26...	153.0	[0..3]	[160..10]
gi\|116070595, gi... - gi\|116070595\|ref\|ZP_01467864.1\| thioredoxin peroxidase [Synechococcus sp. BL107], gi\|116066000\|gb\|EA...	152.0	[0..3]	[160..7]
gi\|33634943, gi\|... - gi\|33863026\|ref\|NP_894586.1\| thioredoxin peroxidase [Prochlorococcus marinus str. MIT 9313], gi\|3363...	152.0	[0..3]	[160..7]
gi\|21912927 - gi\|21912927\|emb\|CAC84143.2\| thioredoxin peroxidase [Nicotiana tabacum]	151.0	[0..3]	[161..78]
gi\|116068112, gi... - gi\|116074890\|ref\|ZP_01472151.1\| thioredoxin peroxidase [Synechococcus sp. RS9916], gi\|116068112\|gb\|E...	151.0	[0..2]	[160..6]
gi\|19698783 - gi\|19698783\|gb\|AAL91102.1\| thiredoxin peroxidase [Acanthocheilonema viteae]	151.0	[0..5]	[160..10]
gi\|17232133, gi\|... - gi\|17232133\|ref\|NP_488681.1\| peroxiredoxin [Nostoc sp. PCC 7120], gi\|17133778\|dbj\|BAB76340.1\| peroxi... gi\|75701970, gi\|... - gi\|75908245\|ref\|YP_322541.1\| Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen... gi\|25285298 - pir\|\|AI2385 peroxiredoxin [imported] - Nostoc sp. (strain PCC 7120)	150.0	[0..3]	[161..11]

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Predicted Domain #1

Region A:
Residues: [1-161]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APIKVGDAIP AVEVFEGEPG NKVNLAELFK GKKGVLFGVP GAFTPGCSKT HLPGFVEQAE  60
   61 ALKAKGVQVV ACLSVNDAFV TGEWGRAHKA EGKVRLLADP TGAFGKETDL LLDDSLVSIF 120
  121 GNRRLKRFSM VVQDGIVKAL NVEPDGTGLT CSLAPNIISQ L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.0
Match:	1oc3A
Description:	HUMAN PEROXIREDOXIN 5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	3.66884588063322	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.8187537496904	bayes_pls_golite062009
protein disulfide oxidoreductase activity	1.47769936616412	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
binding	1.25802922431343	bayes_pls_golite062009
selenium binding	1.1082524159827	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
transcription regulator activity	0.52671047749426	bayes_pls_golite062009
protein binding	0.134341907247724	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: