YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|239782044, gi...
Organism:	Homo sapiens
Length:	272 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|239782044, gi....

Description	E-value	Query Range	Subject Range
gi\|114627460 - gi\|114627460\|ref\|XP_520345.2\| PREDICTED: hypothetical protein [Pan troglodytes]	239.0	[0..7]	[269..315]
RXRG_BOVIN - Retinoic acid receptor RXR-gamma OS=Bos taurus GN=RXRG PE=2 SV=1	238.0	[0..7]	[269..180]
gi\|285012, gi\|54026 - gi\|54026\|emb\|CAA46964.1\| retinoid X receptor-gamma [Mus musculus], pir\|\|S26670 retinoic acid recepto...	236.0	[0..7]	[269..180]
gi\|109019327, gi... - gi\|109019327\|ref\|XP_001085313.1\| PREDICTED: retinoid X receptor, gamma isoform 3 [Macaca mulatta], g...	236.0	[0..7]	[269..180]
gi\|55726030 - gi\|55726030\|emb\|CAH89791.1\| hypothetical protein [Pongo abelii] RXRG_PONAB - Retinoic acid receptor RXR-gamma OS=Pongo abelii GN=RXRG PE=2 SV=1	236.0	[0..7]	[269..180]
RXRG - retinoid X receptor, gamma HGNC:10479\|MIM:1... - X receptor, gamma gi\|190689913, gi... - gi\|190691285\|gb\|ACE87417.1\| retinoid X receptor, gamma protein [synthetic construct], gi\|190689913\|g... gi\|114561087 - gi\|114561087\|ref\|XP_513962.2\| PREDICTED: retinoid X receptor, gamma isoform 2 [Pan troglodytes]	236.0	[0..7]	[269..180]
gi\|74006098 - gi\|74006098\|ref\|XP_859637.1\| PREDICTED: similar to Retinoic acid receptor RXR-gamma (Retinoid X rece...	235.0	[0..7]	[269..263]

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Predicted Domain #1

Region A:
Residues: [1-272]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PESADLRALA KHLYDSYIKS FPLTKAKARA ILTGKTTDKS PFVIYDMNSL MMGEDKIKFK  60
   61 HITPLQEQSK EVAIRIFQGC QFRSVEAVQE ITEYAKSIPG FVNLDLNDQV TLLKYGVHEI 120
  121 IYTMLASLMN KDGVLISEGQ GFMTREFLKS LRKPFGDFME PKFEFAVKFN ALELDDSDLA 180
  181 IFIAVIILSG DRPGLLNVKP IEDIQDNLLQ ALELQLKLNH PESSQLFAKL LQKMTDLRQI 240
  241 VTEHVQLLQV IKKTETDMSL HPLLQEIYKD LY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.045757
Match:	1k74D
Description:	Peroxisome proliferator activated receptor gamma, PPAR-gamma
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.15996699473685	bayes_pls_golite062009
transcription regulator activity	0.46162010671465	bayes_pls_golite062009
protein binding	0.33427459029264	bayes_pls_golite062009
nucleic acid binding	0.15459949087509	bayes_pls_golite062009
DNA binding	0.14395376162921	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: