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View Structure Prediction Details

Protein: gi|10120636, gi|...
Organism: Homo sapiens
Length: 147 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|10120636, gi|....

Description E-value Query
Range
Subject
Range
gi|47226732 - gi|47226732|emb|CAG07891.1| unnamed protein product [Tetraodon nigroviridis]
154.0 [0..4] [146..2348]
gi|109082372 - gi|109082372|ref|XP_001091462.1| PREDICTED: aggrecan 1 [Macaca mulatta]
152.0 [0..5] [146..1334]
gi|45384426, gi|... - ref|NP_990286.1| chondroitin sulfate proteoglycan core protein [Gallus gallus], gi|1699007|gb|AAC60...
152.0 [0..4] [146..1896]
gi|57047785 - gi|57047785|ref|XP_536187.1| PREDICTED: similar to Aggrecan core protein precursor (Cartilage-specif...
151.0 [0..5] [146..2122]
ACAN - aggrecan
151.0 [0..5] [146..2205]
PGCA_MOUSE - Aggrecan core protein OS=Mus musculus GN=Acan PE=1 SV=1
150.0 [0..3] [146..1920]
PGCA_BOVIN - Aggrecan core protein OS=Bos taurus GN=ACAN PE=1 SV=3
150.0 [0..5] [146..2154]

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Predicted Domain #1
Region A:
Residues: [1-147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIPKCPEDWG ASSRTSLCFK LYAKGKHEKK TWFESRDFCR ALGGDLASIN NKEEQQTIWR  60
   61 LITASGSYHK LFWLGLTYGS PSEGFTWSDG SPVSYENWAY GEPNNYQNVE YCGELKGDPT 120
  121 MSWNDINCEH LNNWICQIQK GQTPKPD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.154902
Match: 1eggA
Description: Macrophage mannose receptor, CRD4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sugar binding 4.25427593970895 bayes_pls_golite062009
carbohydrate binding 3.65149893663837 bayes_pls_golite062009
monosaccharide binding 3.38024801519156 bayes_pls_golite062009
polysaccharide binding 2.78053603738148 bayes_pls_golite062009
sialic acid binding 2.70278030510986 bayes_pls_golite062009
glycosaminoglycan binding 2.5972853963145 bayes_pls_golite062009
pattern binding 2.50071583096866 bayes_pls_golite062009
binding 1.77303592925534 bayes_pls_golite062009
extracellular matrix structural constituent 1.50055350076635 bayes_pls_golite062009
hyaluronic acid binding 1.45854626657646 bayes_pls_golite062009
receptor binding 1.13770696717742 bayes_pls_golite062009
oligosaccharide binding 0.718827015320259 bayes_pls_golite062009
protein binding 0.622587530215903 bayes_pls_golite062009
mannose binding 0.522340540326499 bayes_pls_golite062009
integrin binding 0.198144305823921 bayes_pls_golite062009
receptor activity 0.180262004156979 bayes_pls_golite062009
galactose binding 0.17307731396675 bayes_pls_golite062009
molecular transducer activity 0.147767214030612 bayes_pls_golite062009
signal transducer activity 0.147767214030612 bayes_pls_golite062009

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