YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7245349, gi\|7...
Organism:	Saccharomyces cerevisiae
Length:	161 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7245349, gi|7....

Description	E-value	Query Range	Subject Range
gi\|151942856 - gi\|151942856\|gb\|EDN61202.1\| protein tyrosine phosphatase [Saccharomyces cerevisiae YJM789] gi\|190408009 - gi\|190408009\|gb\|EDV11274.1\| 18 kDa phosphotyrosine phosphatase [Saccharomyces cerevisiae RM11-1a] LTP1 - Protein phosphotyrosine phosphatase of unknown cellular role; activated by adenine PPAL_YEAST - Low molecular weight phosphotyrosine protein phosphatase OS=Saccharomyces cerevisiae (strain ATCC 20...	182.0	[0..1]	[161..1]
stp1 - low molecular weight phosphotyrosine protein phosphatase PPAL_SCHPO - Low molecular weight phosphotyrosine protein phosphatase OS=Schizosaccharomyces pombe (strain 972 / ...	179.0	[0..4]	[160..1]
gi\|196157007, gi... - gi\|88796535\|ref\|ZP_01112201.1\| phosphotyrosine protein phosphatase [Alteromonas macleodii 'Deep ecot...	178.0	[0..4]	[160..1]
gi\|44982246 - gi\|44982246\|gb\|AAS51555.1\| ADL365Wp [Ashbya gossypii ATCC 10895] gi\|44982246, gi\|... - gi\|45187508\|ref\|NP_983731.1\| ADL365Wp [Ashbya gossypii ATCC 10895], gi\|44982246\|gb\|AAS51555.1\| ADL36...	178.0	[0..4]	[161..1]
gi\|78211969, gi\|... - gi\|78211969\|ref\|YP_380748.1\| protein tyrosine phosphatase [Synechococcus sp. CC9605], gi\|78196428\|gb...	176.0	[0..8]	[160..2]
gi\|47717986, gi\|... - gi\|47717986\|gb\|AAH70999.1\| LOC100137613 protein [Xenopus laevis], gi\|16943637\|gb\|AAK83457.1\| low mol...	176.0	[0..1]	[159..1]
gi\|25289041 - pir\|\|AD2905 protein tyrosine phosphatase [imported] - Agrobacterium tumefaciens (strain C58, Dupont) gi\|17741182, gi\|... - gi\|17936552\|ref\|NP_533342.1\| protein tyrosine phosphatase [Agrobacterium tumefaciens str. C58], gi\|1...	176.0	[0..5]	[159..1]
ACP1 - acid phosphatase 1, soluble	175.0	[0..4]	[159..2]
PPAC_PONPY - Low molecular weight phosphotyrosine protein phosphatase - Pongo pygmaeus (Orangutan) PPAC_PONAB - Low molecular weight phosphotyrosine protein phosphatase OS=Pongo abelii GN=ACP1 PE=2 SV=3	175.0	[0..1]	[159..1]

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Predicted Domain #1

Region A:
Residues: [1-161]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIEKPKISV AFIALGNFCR SPMAEAIFKH EVEKANLENR FNKIDSFGTS NYHVGESPDH  60
   61 RTVSICKQHG VKINHKGKQI KTKHFDEYDY IIGMDESNIN NLKKIQPEGS KAKVCLFGDW 120
  121 NTNDGTVQTI IEDPWYGDIQ DFEYNFKQIT YFSKQFLKKE L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.30103
Match:	1d1pA
Description:	Tyrosine phosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoprotein phosphatase activity	6.88246946508693	bayes_pls_golite062009
phosphatase activity	6.45415826301085	bayes_pls_golite062009
phosphoric ester hydrolase activity	6.24793868976995	bayes_pls_golite062009
protein tyrosine phosphatase activity	5.42677419561083	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	5.27901564747165	bayes_pls_golite062009
hydrolase activity	3.65742648154352	bayes_pls_golite062009
catalytic activity	1.99182579317454	bayes_pls_golite062009
binding	1.7522117458664	bayes_pls_golite062009
transcription regulator activity	0.628751319213679	bayes_pls_golite062009
acid phosphatase activity	0.62303289859123	bayes_pls_golite062009
nucleic acid binding	0.557666750724006	bayes_pls_golite062009
DNA binding	0.357202336581626	bayes_pls_golite062009
protein binding	0.332591807861153	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: